Thisvolumeconsistsofpapersselectedfromthe presentationsgivenatthe Int- national Workshop and Symposium on "Applications of Graph Transformation with Industrial Relevance" (AGTIVE 2003). The papers underwent up to two additional reviews. This volume contains the revised versions of these papers. AGTIVE2003wasthesecondeventoftheGraphTransformationcommunity. The aim of AGTIVE is to unite people from research and industry interested in the application of Graph Transformation to practical problems. The ?rst wo- shoptookplaceatKerkrade,TheNetherlands.Theproceedingsappearedasvol. 1779ofSpringer-Verlags'sLectureNotesinComputerScienceseries.Thissecond workshop, AGTIVE 2003, was held in historic Charlottesville, Virginia, USA. Graphs constitute well-known, well-understood, and frequently used means to depict networks of related items in di?erent application domains. Various typesofgraphtransformationapproaches- alsocalledgraphgrammarsorgraph rewriting systems - have been proposed to specify, recognize, inspect, modify, anddisplaycertainclassesofgraphsrepresentingstructuresofdi?erentdomains. Research activities based on Graph Transformations (GT for short) cons- tute a well-established scienti?c discipline within Computer Science. The int- national GT research community is quite active and has organized international workshops and the conference ICGT 2002. The proceedings of these events, a three volume handbook on GT, and books on speci?c approaches as well as big application projects give a good documentation about research in the GT ?eld (see the list at the end of the proceedings). The intention of all these activities has been (1) to bring together the - ternational community in a viable scienti?c discussion, (2) to integrate di?erent approaches, and (3) to build a bridge between theory and practice.