Volume 1 of the Handbook of Neuropsychology contains 17 chapters divided into two sections. "Section 1: Introduction" presents the views of various authors discussing practical and theoretical issues of general interest and two chapters cover clinical evaluation in a novel and comprehensive fashion. A feature of Neuropsychology in recent years, the spectacular comeback of single case studies, is covered in a chapter on statistical approaches comparing statistical procedures appropriate for groups to that of single cases. Through two different points of view the important topic of Hemispheric specialization is examined and several chapters deal with the application of theoretical models to neuropsychology in its daily and research aspects. "Section 2: Attention" examines selective attention with chapters on visuo/spatial attentional phenomena and the temporal aspects of attention. The phenomenon of failure to orient, neglect and neglect related phenomena are dealt with in a separate chapter as is the anatomy and the neurophysiological properties of the circuits whose lesion produces neglect deficits in primates.

The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more. Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders.

The Handbook of Clinical Neurology volumes on Traumatic Brain Injury (TBI) provide the reader with an updated review of emerging approaches to TBI research, clinical management and patient rehabilitation. Chapters in Part II offer coverage of clinical sequelae and long-term outcome, brain plasticity and long-term risks, and clinical trials. Contemporary investigations on blast injury and chronic traumatic encephalopathy are presented, making this state-of-the-art volume a must have for clinicians and researchers concerned with the clinical management, or investigation, of TBI.

The Handbook of Clinical Neurology volume on traumatic brain injury (TBI) provides the reader with an updated review of emerging approaches to traumatic brain injury (TBI) research, clinical management and rehabilitation of the traumatic brain injury patient. Chapters in this volume range from epidemiology and pathological mechanisms of injury, and neuroprotection to long-term outcomes with a strong emphasis on current neurobiological approaches to describing the consequences and mechanisms of recovery from TBI. The book presents contemporary investigations on blast injury and chronic traumatic encephalopathy, making this state-of-the-art volume a must have for clinicians and researchers concerned with the clinical management, or investigation, of TBI.

The sixth volume of the Handbook is devoted to topics related to aging and dementia. The volume is introduced by two chapters dealing with age-related cognitive and neurobiological alterations in animals, including a detailed review of data obtained with transgenic and knockout technology. The next chapter reviews the cognitive changes associated with normal aging. The gamut of symptoms that occur in Alzheimer's disease (AD) are then described and analyzed, they include effects on attention, language, memory, non-verbal functions with emphasis on spatial abilities, olfaction and the motor system. The discussion of dementia syndromes is presented in two sections. The first concerns AD, which is discussed from the points of view of epidemiology, neuropathology and neurochemistry and concludes with a review of current and future treatments. The other section deals with non-AD dementias including Fronto-temporal and Lewy body dementias and specific conditions such as Parkinson's and Huntington's disease, as well as HIV infection. The volume includes a review of brain imaging and cerebral metabolism findings in aging and dementia. The final chapters review the relations between culture and dementia and the special syndrome of severe dementia.