The continuing emergence and evolution of tick-borne diseases has significant implications for animal health, the profitability of food animal production and for human health, with many tick-borne diseases having zoonotic capability. These problems are being exacerbated as previously exotic-based ticks spread northwards, carrying diseases. This book is an expansion of the EFSA report on the subject, and includes coverage of the significance of tick-borne diseases, identification of tick species, emerging tick-borne infections, factors influencing the spread and distribution of ticks and surveillance and control measures.