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"In his now celebrated lecture at the 1959 meeting of the American Physical Society, Richard Feynman pondered the potential of miniaturization in the physical sciences. His vision, based on known technology, examined the limits set by physical principles and proposed a variety of new nano-tools including the concept of ""atom-by-atom"" fabrication. In the intervening decades, many of these predictions have become reality. In particular, the development and application of nanofluidics is becoming a competitive and exciting field of research. These nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency. In a fundamental sense, chip-based analytical systems have been shown to have many advantages over their conventional (larger) analogues. Despite the growth of this field, there are surprisingly few books dedicated to nanofluidics. This book will fill the gap in the literature for a text focusing on bioanalytical applications. Written at a level accessible to experts and non-experts alike, it has the potential to become a mainstream text book for advanced nanobiotechnology courses within academic institutions."
Bioanalytical applications in nanopores are an exciting field of research which have seen rapid development over the last ten plus years. This book focuses uniquely on this research area providing an insight from the world leading experts in the area. Based on the proceedings of the 1st International Conference on Nanopores for Bioanalytical Applications (Lanzarote, 2012), it will provide a snapshot of this exciting field for the nanopores community. It describes the latest experimental and fabrication protocols necessary to carry out nanopore-based experiments and covers a wide variety of topics. These include: biological pores, solid state pores, hybrid structures, fundamental aspects, work on the underlying (bio)physics and applications in biosensing and DNA sequencing. The multidisciplinary approach to this topic makes the book suitable for readers in both academia and industry.
There has been significant growth in the field of nanofluidics, where nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency and have many advantages over their conventional (larger) analogues. The new edition of Nanofluidics has been fully revised and updated with the latest advancements and applications. With a focus on bioanalysis, specific applications are given with case studies. The end of each chapter now also features a methodology section to explain experimental protocols and "tips and tricks". The editors draw on an international authorship and provide a handbook for the community. Written at an accessible level the book is suitable for both experts and non-experts alike.
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