This issue of Chest Medicine Clinics focuses on Respiratory Manifestations of Neuromuscular and Chest Wall Disease, with topics including: Respiratory Pathophysiology of CW; Respiratory Pathophysiology of NMDiseases; Sleep Disordered breathing in NMDs and CW; PFT Measurements in NMD and CW disorders; Assessing diaphragm function in chest wall and neuromuscular disease; Disorders of the Diaphragm; Disorders of the CW; Muscular Dystrophies; Respiratory Issues in Amyotrophic Lateral Sclerosis; Metabolic myopathies and the Respiratory System; Respiratory complications of SCI; Obesity hypoventilation syndrome; NIV in NMD and CW; Swallowing and Secretion Management Issues in Neuromuscular Disease; Advances in Cell and Molecular Biology in NMD; and Diaphragm Pacing.