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Pattern Recognition in Bioinformatics - 4th IAPR International Conference, PRIB 2009, Sheffield, UK, September 7-9, 2009, Proceedings (Paperback, 2009 ed.)
Visakan Kadirkamanathan, Guido Sanguinetti, Mark Girolami, Mahesan Niranjan, Josselin Noirel
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The Pattern Recognition in Bioinformatics (PRIB) meeting was
established in 2006 under the auspices of the International
Association for Pattern Recognition (IAPR) to create a focus for
the development and application of pattern recognition techniques
in the biological domain. PRIB's aim to explore the full spectrum
of pattern recognition application was re?ected in the breadth of
techniquesrepresented in this year's subm- sions and in this book.
These range from image analysis for biomedical data to systems
biology. We
werefortunatetohaveinvitedspeakersofthehighestcalibredeliveringkeynotes
at the conference. These were Pierre Baldi (UC Irvine), Alvis
Brazma (EMBL-EBI), GunnarRats .. ch(MPITubi ..
ngen)andMichaelUnser(EPFL).Weacknowledgesupportof
theEUFP7NetworkofExcellencePASCAL2forpartiallyfundingtheinvitedspeakers.
Immediately prior to the conference, we hosted half day of tutorial
lectures, while a special session on "Machine Learningfor
IntegrativeGenomics" was held immediately after the main
conference.Duringthe conference,a poster session was heldwith
further discussion.
Wewouldlikeonceagaintothankalltheauthorsforthehighqualityofsubmissions,
as well as Yorkshire South and the University of Shef?eld for
providing logistical help in organizing the conference. Finally, we
would like to thank Springer for their help in assembling this
proceedings volume and for the continued support of PRIB.
New insights into modern medicine and systems biology are enabled
by innovative protocols and advanced technologies in mass
spectrometry-based proteomics. This volume details new pipelines,
workflows, and ways to process data that allow for new frontiers in
proteomics to be pushed forward. With applications to biomarker
discovery, interactions between proteins, between biological
systems, dynamics of post-translational modifications among others,
new protocols have been developed and iteratively refined to probe
the endless complexity of the proteome in ever greater details.
This volume deals with methods for data dependent and data
independent mass spectrometry analyses. Valuable, first-hand
information is provided from designing experiments, sample
preparation and analysis, exploitation of public datasets and
carrying out reproducible data pipelines, using modern
computational tools such as Galaxy or Jupyter. Written in the
highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls. Authoritative and cutting-edge, Mass
Spectrometry of Proteins: Methods and Protocols aims to ensure
successful results in the further study of this vital field.
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