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Increasing survival figures and the use of more intense combined
treatment regimens in modern oncology have raised the problem of
late therapeutic sequelae in long-term survivors after cancer.
Recent scientific approaches to late sequelae concentrate on the
evaluation of subclinical changes with sophisticated functional
measurements and experimental investigation of the underlying
pathophysiological mechanisms.
The objective of the book is to bring together these recent
clinical and experimental data from different medical disciplines
to give an overview of the most relevant problems of late sequelae.
In clinical practice the book may help regarding estimation of
risks, selection of diagnostic methods, and estimation of the
prognosis of late sequelae.
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