In this richly illustrated book, the contributors describe the Mereon Matrix, its dynamic geometry and topology. Through the definition of eleven First Principles, it offers a new perspective on dynamic, whole and sustainable systems that may serve as a template information model. This template has been applied to a set of knowledge domains for verification purposes: pre-life-evolution, human molecular genetics and biological evolution, as well as one social application on classroom management.The importance of the book comes in the following ways:

This Handbook provides a complete compendium of methods for evaluation of IT-based systems and solutions within healthcare. Emphasis is entirely on assessment of the IT-system within its organizational environment. The author provides a coherent and complete assessment of methods addressing interactions with and effects of technology at the organizational, psychological, and social levels.
It offers an explanation of the terminology and theoretical foundations underlying the methodological analysis presented here. The author carefully guides the reader through the process of identifying relevant methods corresponding to specific information needs and conditions for carrying out the evaluation study. The Handbook takes a critical view by focusing on assumptions for application, tacit built-in perspectives of the methods as well as their perils and pitfalls.
*Collects a number of evaluation methods of medical informatics
*Addresses metrics and measures
*Includes an extensive list of anotated references, case studies, and a list of useful Web sites