Buffalo is the most common milch animal reared after cattle in the world Buffalo has unique ability to utilize coarse feed straw and crop residue and convert them into protein and fat rich lean meat. Today, in buffalo rearing countries, buffalo is recognizing as farmers milk machine. The reproductive performance of buffaloes is not good as compared to the cattle. There are many ways to improve the reproductive performance in buffaloes. The one is proper postpartum management and weaning of buffalo calves. Weaning not only improves the reproductive performance but also increases the milk production and milk yield. This book will help to the buffalo farmers and buffalo researchers how to wean the buffalo calves, period of weaning and alternative milk replacers to calves to increase the reproductive and productive performance in cost effective manner.