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In search for new enzyme inhibitors of therapeutic importance, the
present study was designed to find inhibitors of two enzymes of
therapeutic significance, i.e., Lipoxygenase (EC 1.13.11.12) and
NTPDase (Nucleoside triphosphate diphosphohydrolases) (EC 3.6.1.5)
enzymes from extracts of medicinal plants used in folk medicine.
Lipoxygenase inhibitors are involved in many inflammatory diseases,
asthma, cancer, increase immune response to viral and bacterial
infection, leukemia, lymphoma and autoimmune disorders. NTPDase
inhibitors are currently target for various cardiovascular diseases
and some types of cancer.
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