Rainwater tank systems have been widely adopted across the world to provide a safe local source of water in underdeveloped rural areas, a substitution for mains water for non potable end uses in water stressed urban areas, as well as providing flooding control in monsoonal climates such as Korea, or combined sewer systems such as Germany. The importance of these systems in cities has grown, as water managers seek to provide a range of decentralised solutions to supply constraints of current water supply systems, whilst reducing the impact of urban development on the natural environment, and increasing resilience to the impacts of climate change. Rainwater tank systems are now often implemented under integrated urban water management (IUWM) and water sensitive urban design (WSUD) philosophies, which take a holistic view of the urban water cycle. Rainwater Tank Systems for Urban Water Supply is based on a comprehensive, multi-million dollar research program that was undertaken in South East Queensland (SEQ) Australia in response to the Millennium drought when the water supply level in the regions drinking water dams dropped to 17% in July 2007 and the area came close to running out of water. In particular, the book provides insights and detailed analysis of design, modelling, implementation, operation, energy usage, economics, management, health risk, social perceptions and implications for water quality/quantity of roof water runoff. The approaches and methodologies included in Rainwater Tank Systems for Urban Water Supply inform and validate research programs, and provide insights on the expected performance and potential pitfalls of the adoption of rainwater tanks systems including: actual harvested yield and resulting mains water savings, optimal sizing for rainwater storages and roof collection systems, expected water quality and implications for managing public health risks, modelling tools available for decision support, operation and management approaches of a decentralised asset at the household scale and community acceptance. The book is suitable for use at undergraduate and post graduate levels and is of particular interest to water professionals across the globe, who are involved in the strategic water planning for a town, city or a region. It is a valuable resource for developers, civil designers, water planners, architects and plumbers seeking to implement sustainable water servicing approaches for residential, industrial and commercial developments.

Topical and transdermal drug delivery systems (TDDs) have several advantages over traditional drug delivery methods, as they can be less invasive, more sanitary, more cost-effective, and may result in better patient compliance. TDDs play a significant role in therapeutics with a variety of preparations and approaches designed by expert formulation scientists. This volume integrates a wide variety of case studies, research, and theories to reveal their diversity and capture the novel approaches of transdermal and topical drug delivery employed by developers and content experts in the field. It provides an abundance of important information and state-of-the-art research on topical and transdermal drug delivery systems and addresses the basics of drug delivery systems, strategies to enhance permeation across membranes, and formulation and evaluation of diverse dosage forms. The volume presents an evaluation of the pros and cons of conventional drug delivery systems against TDDs and discusses the nuances of micro- and nano-systems in TDDs. The extraordinary packages of nano systems (vesicular systems, polymeric nanoparticles, nanoemulsion and dendrimers) are broadly discussed, and their applications are reviewed through a transdermal route. The book looks at TDDs and the main nanoparticles used in skin diseases and lesions of the aging, such as psoriasis, vitiligo, cancer, lesions of the aging and others. Chapters also discuss polymeric micelles in topical and transdermal delivery; microneedles; emulsion, nanoemulsion and microemulsion; TDDs in pulmonary drug delivery systems; nanoencapsulated nasal drug delivery systems; skin sensitivity and irritation testing for transposing transdermal drug delivery systems; and regulatory aspects of drug development for dermal products. Topical and Transdermal Drug Delivery Systems: Applications and Prospects will be a valuable resource for pharmaceutical scientists and researchers, industry professionals, and academicians and students of the pharmaceutical and biomedical sciences.

The text focuses on mathematical modeling and applications of advanced techniques of machine learning, and artificial intelligence, including artificial neural networks, evolutionary computing, data mining, and fuzzy systems to solve performance and design issues more precisely. Intelligent computing encompasses technologies, algorithms, and models in providing effective and efficient solutions to a wide range of problems including the airport's intelligent safety system. It will serve as an ideal reference text for senior undergraduate, graduate students, and academic researchers in fields including industrial engineering, manufacturing engineering, computer engineering, and mathematics. The book- Discusses mathematical modeling for traffic, sustainable supply chain, vehicular Ad-Hoc networks, internet of things networks with intelligent gateways. Covers advanced machine learning, artificial intelligence, fuzzy systems, evolutionary computing, data mining techniques for real-world problems. Presents applications of mathematical models in chronic diseases such as kidney and coronary artery diseases. Highlights advances in mathematical modeling, strength, and benefits of machine learning and artificial intelligence, including driving goals, applicability, algorithms, and processes involved. Showcases emerging real-life topics on mathematical models, machine learning, and intelligent computing using an interdisciplinary approach. The text presents emerging real-life topics on mathematical models, machine learning, and intelligent computing in a single volume. It will serve as an ideal text for senior undergraduate, graduate students, and researchers in diverse fields domains including industrial and manufacturing engineering, computer engineering, and mathematics.

This new volume on applications and advances in tissue engineering presents significant, state-of-the-art developments in this exciting area of research. It highlights some of the most important applied research on the applications of tissue engineering along with its different components, specifically different types of biomaterials. It looks at the various issues involved in tissue engineering, including smart polymeric biomaterials, gene therapy, tissue engineering in reconstruction and regeneration of visceral organs, skin tissue engineering, bone and muscle regeneration, and applications in tropical medicines. Covering a wide range of issues in tissue engineering, the volume Provides an overview of the efficacy of the different biomaterials employed in tissue engineering (such as skin regeneration, nerve regeneration, artificial blood vessels, bone regeneration). Looks at smart polymeric biomaterials in tissue engineering Discusses the hybrid approach of tissue engineering in conjunction with gene therapy Explores using tissue engineering in the management of tropical diseases Considers various skin tissue engineering applications, including wound healing methods, skin substitutes and other materials Reports on the use of various biomaterials in bone and muscle regeneration Describes the use of tissue engineering in reconstruction and regeneration of visceral organs Covers polysaccharides and proteins-based hydrogels for tissue engineering applications Providing an abundance of advanced research and information, Tissue Engineering: Applications and Advancements will be a valuable resource for medical researchers, pharmaceutical manufacturers, healthcare personnel, and academicians.

Plasmonics stems from the surface charge density oscillations at metal–dielectric interface, leading to extremely strong light–matter interactions. In the past few decades, plasmonics has become one of the most favorite fields/techniques in realizing high-performance photonic devices. For this purpose, different new concepts, such as exploration of different radiation frequency regions, two-dimensional materials/heterostructures, and different types of substrates for the excitation of plasmons have been investigated for plasmonics-based sensors and detectors. This book focuses on the recent and advanced works on optical sensors and detectors utilizing plasmonic techniques for opto-electronic applications. The book is unique as it describes both sensors and detectors based on plasmonics and their practical applications in a single book, a feature not found in any book so far.

Green Chemistry practices and principals can play an important role in achieving the UN SDGs. The expert contributors here have selected key goals and review the implementation of green chemistry for these goals. As described by the UN, it is crucial to harmonize three core elements: economic growth, social inclusion and environmental protection. The Sustainable Development Goals embrace the sustainability mindset and this will lead to greater productivity and a greener environment. For sustainable development to be achieved, these elements are interconnected and all are crucial for the well-being of individuals and societies. The chapters explore sustainable development through green engineering. Demonstrates the progress made in the search for processes that use fewer toxic chemicals, and produce less waste while using less energy. Highlights the importance of chemistry to everyday life and demonstrates the benefits the exploitation of green chemistry can have for society. The pollution of water is of the utmost concern globally and bioremediation has a strong role to play in ensuring adequate supplies of high quality water. These unique volumes address the vast interest in green chemistry and clean processes which has grown significantly in recent years.

Bioremediation: A Sustainable Approach to Preserving Earth's Water discusses the latest research in green chemistry practices and principles that are involved in water remediation and the quality improvement of water. The presence of heavy metals, dyes, fluoride, dissolved solids and many other pollutants are responsible for water pollution and poor water quality. The removal of these pollutants in water resources is necessary, yet challenging. Water preservation is of great importance globally and researchers are making significant progress in ensuring this precious commodity is safe and potable. This volume illustrates how bioremediation in particular is a promising green technique globally. Features: Addresses bioremediation of all the major water pollutants Approaches the chemistry of water and the concept of water as a renewable resource from a green chemistry aspect Discusses environmental chemistry and the practice of industrial ecology Explains the global concern of adequate high quality water supplies, and how bioremediation can resolve this Explores sustainable development through green engineering

This new volume, Promising Drug Molecules of Natural Origin, explores potential beneficial drug substances derived from nature. It presents the general principles, characteristics, evaluation techniques, and applications involved in drug molecules from natural sources, such as plants and marine life. With chapters from renowned experts from around the world, the chapters in this volume address the challenges of standardization of herbal medicines, methods of characterization of natural medicines and phyto-constituents, and quality control methods for herbal medicines. Several chapters in the book focus on the evolution of phyto-constituents in cancer therapeutics, while others deal with applications for other diseases, such as diabetes and neuroinflammatory disorders. The volume also specifically reviews heterocyclic drugs from plants. This volume will be a valuable resource for faculty and advanced students in pharmaceutics as well as researchers, scientists, and industry professionals in medicine and drug development.

This volume addresses efforts to overcome the shortcomings of conventional dosage forms by exploiting the principles of nanoscience to deliver drugs for medical treatment. Nanodispersions are an important aspect because they possess globules/particles in sizes usually below 1000 nm in which the drug is dispersed in a continuous medium employing surface-active agents as stabilizers. With chapters written by experienced scientists and researchers in the field, this volume provides an abundance of information on various aspects of nanodispersions for drug delivery. The book is divided into several sections: nanoemulsions, nanosuspensions, and diverse dispersed systems. The chapters detail what nanodispersions have demonstrated in the past and what they are expoected to continue to do in the future as the technology further evolves. Key features: * Provides an overview of nanoemulsions for drug delivery * Introduces the general principles, classification, and methods of preparation of nanoemulsion-based drug delivery systems * Presents information relevant to specific routes of applications of nanoemulsions * Looks at the various aspects of nanosuspensions, including their formulation components, preparation methods, unique features, methods of characterization, and applications in various routes of administration * Explores nanomicellar approaches for drug delivery * Discusses the preparation, applications, and clinical considerations of nanogels for drug delivery

Projects the genesis of green chemistry in an effective manner, with the use of relevant timelines and incidents that necessitated the birth of this fieldExemplifies how waste can not only be reduced or eliminated but can, in fact, be utilized as a precious resource for the creation of valuables, thereby preaching the concept of atom economyHighlights cutting-edge greener technologies such as green catalysts, green solvents, and green energyDiscusses in detail the implementation of green chemistry in the form of interesting real-world case studies that have won the US Presidential Green Chemistry Challenge AwardsElaborates how green chemistry has been incorporated in practice and teaching at the international as well as national levelEffectively disseminates future green technologies, including biomimicry, continuous flow methodologies, and miniaturization Presents interesting facts and unusual findings in the form of add-ons in each chapter to enhance the knowledge of studentsProvides learning outcomes and problems at the end of each chapter

This new volume, Nanocarriers for Brain Targeting: Principles and Applications, covers recent research on brain physiology and the development of drug delivery systems. It explores a diverse variety of strategies that can be employed to achieve drug targeting to the brain. The nanocarriers that are discussed include nanoparticles, vesicular carriers, carriers having carbon as a core constituent, dispersed systems, and more. The inherent anatomy and physiology of the brain renders it different from other organs. The past few decades have witnessed significant research on brain ailments in response to a majority of hospitalizations that occur due to age-related central nervous system disorders. The prevalence of diverse diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, HIV-dementia, etc., affect about 1.5 billion people globally, which is further anticipated to reach 1.9 billion by the year 2020. Nanocarriers for drug delivery to the brain are seen as one of the answers to this growing problem.

This new volume presents a plethora of new research on the use of nanoconjugate nanocarriers in drug delivery. Nanotechnology as drug carriers has been observed to increase the level of sophistication through a variety of ways. It helps to alleviate some of the pitfalls of conventional dosage forms, such as few pitfalls such as non-specific drug delivery, dose dumping, poor patient compliance, toxicities linked with higher doses, etc. With chapters from highly skilled, experienced, and renowned scientists and researchers, Nanoconjugate Nanocarriers for Drug Delivery is divided into four sections, providing an introduction to nanocarriers for drug delivery, physicochemical features of nanocarriers, and specific applications dealing with drug delivery in particular. The materials used as well as formulation and characterization have been discussed in detail. The nanocarriers covered in the book include nanoparticles, vesicular carriers, carriers having carbon as the core constituent, dispersed systems, etc. The book also delves into the interaction and associations between drug delivery research and its therapeutic applications in practice. The book integrates a wide variety of case studies, research, and theories in an attempt to reveal the diversity and capture the novel approaches of nanoconjugate nanocarriers for drug delivery employed by developers and content experts in the field. This timely publication will be an essential reference and current awareness source, building on the available literature in the field of pharmacy and biomedical science, while also providing ideas for further research opportunities in this dynamic field.

Addressing the increasing popularity of nutraceuticals, dietary supplements, and functional foods, this comprehensive and timely book presents an abundance of information on herbal products and their applications. The chapter authors-highly skilled, experienced, and renowned scientists and researchers from around the globe-offer up-to-date knowledge on the uses of herbal products in health management, in cancer treatment, in mental health therapy, and more. Nutraceuticals and Dietary Supplements: Advances and Applications begins with an introduction, the nomenclature, and characteristics of nutraceuticals and goes on to discuss in-depth applications for specific health issues, including cancer, diabetes, Alzheimer's disease, alcoholism, and more. It also looks at the pros and cons as well as the analytical techniques used for the production of nutraceuticals. Chapters cover market size, regulatory perspectives, manufacturing, and in silico drug design. The book incorporates a wide diversity of case studies, research, and theories pertaining to natural products employed by developers and content experts in the field.

When the Nobel Prize Committee recognized the importance of green chemistry with its 2005 Nobel Prize for Chemistry, this relatively new science came into its own. Although no concerted agreement has been reached yet about the exact content and limits of this interdisciplinary discipline, there seems to be increasing interest in environmental topics that are based on the chemistry embodied in this subject. Linking green chemistry practice to environmental sustainability, Green Chemistry for Environmental Sustainability illustrates the efforts being made to remediate a scathed environment into a pristine one. Links Green Chemistry Practice to Environmental SustainabilityEminent international experts present research on and the application of green chemistry and engineering in addressing current issues of an environmental and social nature. They cover sustainable development and environmental sustainability with chapters on green chemistry and engineering research, the design and synthesis of environmentally benign chemical processes, green approaches to minimize and/or remediate environmental pollution, the development of biomaterials, biofuel, and bioenergy production, biocatalysis, and policies and ethics in green chemistry. The book also explores economics, environmentally benign technologies for greener processes, computational methods and modeling, and green approaches to minimize air and water. Green chemistry has brought a relatively prompt and positive paradigm shift in the overall use and management of natural resources and raw materials for the development of society with a subtle promise to cause far less pronounced harm to the environment. This text provides insight into the chemical and biochemical technologies that are being studied, optimized, and eventually developed to promote environmental sustainability. It provides up-to-date information on selected fields where the principles of green chemistry are being embraced for safeguarding and improving the quality of the environment.

This new volume, Herbal Product Development: Formulation and Applications, addresses some of the challenges that hinder the path of successful natural products from laboratory to market. Highly skilled, experienced, and renowned scientists and researchers from around the globe offer up-to-date information that describes characteristics of herbs and herbal products, applications, evaluation techniques, and more. There is also a section dedicated to alternative medicinal strategies for the treatment and cure of diverse diseases. Also considered, of course, is the efficacy and safety of herbal products, which are of major concern. This valuable volume will be an important addition to the library of those involved in herbal product development and testing, including researchers, scientists, academicians, industry professionals, and students in this area.

This volume is a thorough presentation of the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications. The second of this two-volume set, it addresses the applications of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques. This volume includes 11 chapters that focus on the targeting facet of drug delivery systems. Targeting is a focused maneuver to achieve the specified goals, including achieving the desired result and reaching the specific location. Targeting has now been successfully achieved for several diseases/disorders; however, its role is noteworthy in cancer treatment where chemotherapy is a main course of approach. Nanotechnology-based products have great potential by virtue of their inherent features. This edited book provides a detailed application of nanotechnology in drug delivery systems in health care. The book discusses general principles of drug targeting, material of construction and technological concerns of nanoparticles, and different drug delivery systems and their preparation. Taken together, the informative chapters will provide researchers and scientists as well as faculty and students with valuable research on the effective use of new approaches in advanced drug delivery nanosystems. Volume 1 of the two-volume series is subtitled Novel Drug Carriers. The volumes are available separately or as a set.

With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.

Focusing on nanoparticulate nanocarriers and recent advances in the field of drug delivery, the volume begins with chapters that provide an informative introduction to polymeric nanoparticles-their general physicochemical features and characteristics, their applications in drug delivery systems, and the challenges involved. Specific applications are discussed, with attention paid to treatment of particular diseases and disorders and the targeting of specific organs. Part 2 looks at more specific applications and techniques of nanoparticulate nanocarriers for drug delivery, such as the use of magnetic nanoparticles, gold nanoparticles in therapeutics, and superparamagnetic iron oxide nanoparticles (SPIONs) for the treatment of cancer. Part 3 discusses lipid-based nanoparticulates for various applications, including skin care. The last section of the book explores some of the newer nanoarchitectures, including dendrimers in gene delivery and carbon nanotubes for drug delivery. Together, the insightful research presented here provides valuable information for those involved in this area, including scientists and researchers and faculty and upper-level students, as well as for industry professionals.

J.M.E. McTaggart seeks to critically expound and appraise the British philosopher's thought with respect to three principal themes of his philosophy: substance, self, and immortality. Ramesh Kumar Sharma guides the reader through the labyrinths of McTaggart's intricate arguments and defends many of McTaggart's highly unorthodox doctrines and conclusions. While doing this, Sharma draws on the works of, among others, Berkeley, Hegel, and Leibniz, and at the same time attacks numerous modern-day physicalist theories that propound mind-brain identity as against the presumed reality of the self and consciousness. This work is thus recommended both for philosophers and researchers interested in: (1) such perennial metaphysical subjects as reality, existence, possibility, the basic ontological categories of substance, qualities, and relations (universals); (2) the question of the reality of the self; (3) McTaggart's overall vision of the universe or Absolute, and his rejection of the more or less predominant view that the Absolute is God; (4) McTaggart's unique doctrine, after Plato, of the immortality of the self combined with (the self 's) pre-existence, post-existence, and plurality of lives; and (5) his extraordinary, but important, views on perception.

This volume, the first of the two-volume Drug Delivery Approaches and Nanosystems series, presents a full picture of the state-of-the-art research and development in drug delivery systems using nanotechnology and its applications. It addresses the ever-expanding application of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques. Many methods of drug delivery systems have been used, but very few of them have been validated for medical use. A major reason for the above situation, the editors believe, is the gap between academia and research, and the gap between academic research and real-time clinical applications and needs. This volume addresses that gap. This volume presents 12 chapters that provide information about the preparation and characterization of nanocomposite materials used in drug delivery systems; advanced research of carbon nanotubes, nanocomposite materials, and polymer-clay, ceramics, and silicate glass-based nanocomposites; and the functionality of graphene nanocomposites. The book also provides detailed information on the application of nanotechnology in drug delivery systems in health care systems and medicine. The book describes how nanostructures are synthesized and draws attention to wide variety of nanostructures available for biological research and treatment applications. This valuable volume provides a wealth of information that will be valuable to scientists and researchers, faculty, and students. Volume 2 of the two-volume series is subtitled Drug Targeting Aspects of Nanotechnology. The volumes are available separately or as a set.

This new volume focuses on the ever-growing and ever-sophisticated use of nanobiomaterials in drug delivery. There have been significant developments in the delivery of the active pharmaceutical ingredients to target sites, thereby sparing the normal functioning biological systems from damage, and this volume highlights some of the most important developments in the field. The book first provides an overview of nanobiomaterials and then goes on to report on new developments in drug delivery and nanotechnology, nanobiomaterials as carriers in cancer therapy, and the diverse uses of nanobiomaterials. Broken into sections, the chapters cover: an overview of nanobiomaterials drug delivery and nanotechnology nanobiomaterials as carriers in cancer therapeutics diverse uses of nanobiomaterials This volume will be a valuable resource on drug delivery for pharmaceutical manufacturers, healthcare personnel, and researchers.

Ultrasonic irradiation and the associated sonochemical and sonophysical effects are complementary techniques for driving more efficient chemical reactions and yields. Sonochemistry?the chemical effects and applications of ultrasonic waves?and sustainable (green) chemistry both aim to use less hazardous chemicals and solvents, reduce energy consumption, and increase product selectivity.

A comprehensive collection of knowledge, Handbook on Applications of Ultrasound covers the most relevant aspects linked to and linking green chemistry practices to environmental sustainability through the uses and applications of ultrasound-mediated and ultrasound-assisted biological, biochemical, chemical, and physical processes.

Chapters are presented in the areas of:

• Medical applications
• Drug and gene delivery
• Nanotechnology
• Food technology
• Synthetic applications and organic chemistry
• Anaerobic digestion
• Environmental contaminants degradation
• Polymer chemistry
• Industrial syntheses and processes
• Reactor design
• Electrochemical systems
• Combined ultrasound?microwave technologies

While the concepts of sonochemistry have been known for more than 80 years, in-depth understanding of this phenomenon continues to evolve. Through a review of the current status of chemical and physical science and engineering in developing more environmentally-friendly and less toxic synthetic processes, this book highlights many existing applications and enormous potential of ultrasound technology to upgrade present industrial, agricultural, and environmental processes.

Scientists are conducting active research in different fields of engineering, science and technology by adopting the Green Chemistry Principles and methodologies to devise new processes, with a view to help protect and ultimately save the environment from further anthropogenic interruptions and damage. With this in mind, the book provides an up-to-date, coherently written and objectively presented set of chapters from eminent international researchers who are actively involved in academic and technological research in the synthesis, (bio)degradation, testing and applications of biodegradable polymers and biopolymers. This pool of the latest ideas, recent research and technological progress, together with a high level of thinking with a comprehensive perspective, makes the emerging field of biodegradable polymer science and engineering (or bio-based polymers) linked to environmental sustainability, the essence of this key publication. The handbook consists of chapters written and contributed by international experts from academia who are world leaders in research and technology in sustainability and biopolymer and biodegradable polymer synthesis, characterisation, testing and use. The book highlights the following areas: green polymers; biopolymers and bionanocomposites; biodegradable and injectable polymers; biodegradable polyesters; synthesis and physical properties; discovery and characterization of biopolymers; degradable bioelastomers, lactic acid based biodegradable polymers; enzymatic degradation of biodegradable polymers; biodegradation of polymers in the composting environment; recent development in biodegradable polymers; research and applications and biodegradable foams. The book is aimed at technical, research-orientated and marketing people in industry, universities and institutions. It will also be of value to the worldwide public interested in sustainability issues and biopolymer development as well as others interested in the practical means that are being used to reduce the environmental impacts of chemical processes and products, to further eco-efficiency, and to advance the utilization of renewable resources for a bio-based production and supplier chain. Readers will gain a comprehensive and consolidated overview of the immense potential and ongoing research in bio-based and biodegradable polymer science, engineering and technology to make the world greener.