Oliver James and Eliza Bennett star in this horror from director Johannes Roberts. When a group of friends decide to go on a road trip through scenic Ireland, their journey takes a fortuitous turn as they unintentionally knock down and kill an old gypsy woman. In the woman's dying breath she places upon the group a curse that sends for a gigantic bird of prey known as a Simuroc to deliver their punishment: death, one at a time.

Fourth film in the series based on the popular computer game. Milla Jovovich reprises her role as Alice, who continues to fight against the Umbrella Corporation. Following new information, she heads to Los Angeles where she seeks out any survivors of the T-virus epidemic. Characters Jill Valentine (Sienna Guillory) and Claire Redfield (Ali Larter), who appeared previously in the series, are back to help defeat the Undead. The group of survivors attempt to strengthen their numbers and find refuge, but can they escape the city which is invested with zombies?