Rose has been content to simply gaze upon Sir Harij’s countenance during his visits to drop off the ingredients for the love potion he ordered, so she has no idea what to make of him dropping by just to spend time with her! Afraid that he might discover her feelings, she quickly finishes the potion...but will that truly be the end of their time together?

"I want you to make me a love potion." With that single sentence from the object of her affections, the Good Witch of the Lake's crush ended in heartbreak. In a desperate bid to spend more time with him, she sends him on a wild goose chase for ingredients...but when he starts visiting every day to take care of her, she might have gotten much more than she's bargained for!

This introductory volume provides the basics of surface-knots and related topics, not only for researchers in these areas but also for graduate students and researchers who are not familiar with the field.Knot theory is one of the most active research fields in modern mathematics. Knots and links are closed curves (one-dimensional manifolds) in Euclidean 3-space, and they are related to braids and 3-manifolds. These notions are generalized into higher dimensions. Surface-knots or surface-links are closed surfaces (two-dimensional manifolds) in Euclidean 4-space, which are related to two-dimensional braids and 4-manifolds. Surface-knot theory treats not only closed surfaces but also surfaces with boundaries in 4-manifolds. For example, knot concordance and knot cobordism, which are also important objects in knot theory, are surfaces in the product space of the 3-sphere and the interval.Included in this book are basics of surface-knots and the related topics of classical knots, the motion picture method, surface diagrams, handle surgeries, ribbon surface-knots, spinning construction, knot concordance and 4-genus, quandles and their homology theory, and two-dimensional braids.

This thesis presents the first report of the comprehensive and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53, which plays a central role in maintaining genomic integrity. Inactivation of p53 via mutation of its gene is a key step in tumorigenesis. Biophysical analyses revealed that the stability of the mutant peptides varied widely. Formation of a tetrameric structure is to be critical for protein-protein interactions, DNA binding, and the post-translational modification of p53. A small destabilization of the tetrameric structure therefore could result in dysfunction of tumor suppressor activity. This work suggests that the threshold for loss of tumor suppressor activity, in terms of the disruption of p53's tetrameric structure, could be extremely low. Furthermore, functional control of p53 via tetramer formation was demonstrated, based on the structure-function analysis of mutant p53. The results disclosed that relatively small changes in tetramer formation, induced by the stabilization or inhibition of homo-tetramerization, could control p53 function.

This thesis presents the first report of the comprehensive and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53, which plays a central role in maintaining genomic integrity. Inactivation of p53 via mutation of its gene is a key step in tumorigenesis. Biophysical analyses revealed that the stability of the mutant peptides varied widely. Formation of a tetrameric structure is to be critical for protein-protein interactions, DNA binding, and the post-translational modification of p53. A small destabilization of the tetrameric structure therefore could result in dysfunction of tumor suppressor activity. This work suggests that the threshold for loss of tumor suppressor activity, in terms of the disruption of p53's tetrameric structure, could be extremely low. Furthermore, functional control of p53 via tetramer formation was demonstrated, based on the structure-function analysis of mutant p53. The results disclosed that relatively small changes in tetramer formation, induced by the stabilization or inhibition of homo-tetramerization, could control p53 function.

Surfaces in 4-Space, written by leading specialists in the field, discusses knotted surfaces in 4-dimensional space and surveys many of the known results in the area. Results on knotted surface diagrams, constructions of knotted surfaces, classically defined invariants, and new invariants defined via quandle homology theory are presented. The last chapter comprises many recent results, and techniques for computation are presented. New tables of quandles with a few elements and the homology groups thereof are included.

This book contains many new illustrations of knotted surface diagrams. The reader of the book will become intimately aware of the subtleties in going from the classical case of knotted circles in 3-space to this higher dimensional case.

As a survey, the book is a guide book to the extensive literature on knotted surfaces and will become a useful reference for graduate students and researchers in mathematics and physics.

Surfaces in 4-Space, written by leading specialists in the field, discusses knotted surfaces in 4-dimensional space and surveys many of the known results in the area. Results on knotted surface diagrams, constructions of knotted surfaces, classically defined invariants, and new invariants defined via quandle homology theory are presented. The last chapter comprises many recent results, and techniques for computation are presented. New tables of quandles with a few elements and the homology groups thereof are included.

This book contains many new illustrations of knotted surface diagrams. The reader of the book will become intimately aware of the subtleties in going from the classical case of knotted circles in 3-space to this higher dimensional case.

As a survey, the book is a guide book to the extensive literature on knotted surfaces and will become a useful reference for graduate students and researchers in mathematics and physics.

This book is an introduction to techniques and results in diagrammatic algebra. It starts with abstract tensors and their categorifications, presents diagrammatic methods for studying Frobenius and Hopf algebras, and discusses their relations with topological quantum field theory and knot theory. The text is replete with figures, diagrams, and suggestive typography that allows the reader a glimpse into many higher dimensional processes. The penultimate chapter summarizes the previous material by demonstrating how to braid 3- and 4- dimensional manifolds into 5- and 6-dimensional spaces. The book is accessible to post-qualifier graduate students, and will also be of interest to algebraists, topologists and algebraic topologists who would like to incorporate diagrammatic techniques into their research.

This introductory volume provides the basics of surface-knots and related topics, not only for researchers in these areas but also for graduate students and researchers who are not familiar with the field.Knot theory is one of the most active research fields in modern mathematics. Knots and links are closed curves (one-dimensional manifolds) in Euclidean 3-space, and they are related to braids and 3-manifolds. These notions are generalized into higher dimensions. Surface-knots or surface-links are closed surfaces (two-dimensional manifolds) in Euclidean 4-space, which are related to two-dimensional braids and 4-manifolds. Surface-knot theory treats not only closed surfaces but also surfaces with boundaries in 4-manifolds. For example, knot concordance and knot cobordism, which are also important objects in knot theory, are surfaces in the product space of the 3-sphere and the interval.Included in this book are basics of surface-knots and the related topics of classical knots, the motion picture method, surface diagrams, handle surgeries, ribbon surface-knots, spinning construction, knot concordance and 4-genus, quandles and their homology theory, and two-dimensional braids.

This is the first in-depth examination of "half-Japanese" girls in Japan focusing on ethnic, gendered and embodied 'hybrid' identities. Challenging the myth of Japan as a single-race society, these girls are seen struggling to positively manoeuvre themselves and negotiate their identities into positions of contestation and control over marginalizing discourses which disempower them as 'others' within Japanese society as they begin to mature. Paradoxically, at other times, within more empowering alternative discourses of ethnicity, they also enjoy and celebrate cultural, symbolic, social and linguistic capital which they discursively create for themselves as they come to terms with their constructed identities of "Japaneseness", "whiteness" and "halfness/doubleness". This book has a colourful storyline throughout - narrated in the girls' own voices - that follows them out of childhood and into the rapid physical and emotional growth years of early adolescence.

This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ++++ The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to ensure edition identification: ++++ The Idea Of God John Fiske, Ishiro Kamada Keiseisha, 1894 Religion; Religion & Science; God; Religion / Religion & Science; Religion and science

In 2013, while visiting her sister in the United States, Laurel Kamada collapsed. Far from her husband, son, career, and home in Japan, she spent the next few weeks in a coma from a stroke that left a hole the size of a baseball in the center of her brain. In this multicultural memoir, Kamada writes about her years of recovery with a profound sense of grace, still seeing the beauty in her life while not shying away from its many struggles. This five-part memoir addresses the basics of strokes; an East-West (Japan, U.S.) comparison of stroke, advice and help for the primary caregivers and families of stroke survivors, and lessons on how to improve systems of care and rehabilitation. Kamada also introduces networking means and advice to help stroke survivors, their families and friends, and professionals working in long-term care facilities, such as nursing and rehabilitation staff.

Pictorial representations are very useful for humans to understand complicated relations or structures. This is the reason that the user interface of information systems is strongly required to visualize many kinds of information in a wide variety of graphical forms. At present, however, only some very specialized visualization techniques have been developed probably because the generality in the visualization has not been appreciated correctly. This book presents a visualization framework for translating abstract objects and relations, typically represented in textual forms, into pictorial representations, and describes a general visualization interface based on this framework. In the framework, abstract objects and relations are mapped to graphical objects and relations by user-defined mapping rules. The declarative nature of the mapping rules provides users with more global and more flexible layout capabilities. Also presented is an algorithm for drawing general undirected graphs which can be used to visualize network structures as network diagrams. The proposed visualization framework is shown to be general enough to be applied to various types of visualization problems, such as the visualization of semantics of natural language sentences, the generation of diagrams for data structures and program structures, and the drawing of database schema. Examples of all these problems are shown with actual mapping rules and pictorial results.