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Memory Mechanisms is an edited review volume that summarizes
state-of-the-art knowledge on memory mechanisms at the molecular,
cellular and circuit level. Each review is written by leading
experts in the field, presenting not only current knowledge, but
also discussing the concepts, providing critical reflections and
suggesting an outlook for future studies. The memory mechanisms are
also discussed in the context of diseases. Studies of memory
deficits in disease models are introduced as well as approaches to
restore memory deficits. Finally, the impact of contemporary memory
research for psychiatry is illustrated.
This book integrates discoveries from recent years to show the
diversity of molecular mechanisms that contribute to memory
consolidation, reconsolidation, extinction, and forgetting. It
provides a special focus on the processes that govern functional
and structural plasticity of dendritic spines. In nine chapters,
new and important ideas related to learning and memory processes
will be presented. Themes discussed include the role of AMPA
receptors in memory, two signalling cascades involved in local
spine remodelling and memory, the role of extracellular matrix
proteins in memory, the regulation of gene expression and protein
translation, and mechanisms of retrieval-induced memory modulation
and forgetting. We believe that the study of these topics
represents a great step toward understanding the complexity of the
brain and the processes it governs.
This book integrates discoveries from recent years to show the
diversity of molecular mechanisms that contribute to memory
consolidation, reconsolidation, extinction, and forgetting. It
provides a special focus on the processes that govern functional
and structural plasticity of dendritic spines. In nine chapters,
new and important ideas related to learning and memory processes
will be presented. Themes discussed include the role of AMPA
receptors in memory, two signalling cascades involved in local
spine remodelling and memory, the role of extracellular matrix
proteins in memory, the regulation of gene expression and protein
translation, and mechanisms of retrieval-induced memory modulation
and forgetting. We believe that the study of these topics
represents a great step toward understanding the complexity of the
brain and the processes it governs.
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