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'A lively study of the Big C, which makes the case that cancer is
the price we pay for our marvellously complicated bodies.' The
Times, best books of 2020 'This book is packed with big ideas about
life. Every chapter has something in it which made me think wow.
Having worked in a major cancer charity for many years, Arney
writes with genuine in-depth understanding and is a perfect guide.'
Daniel M. Davis, author of The Beautiful Cure 'Rebel Cell is a
bright, engaging read, fizzing with energy and metaphor. Kat Arney
is a science writer for all of us - a powerful and talented story
teller.' Stephen McGann 'Kat's book is Dynamite. A crystal clear
reappraisal of the story behind that word we fear to mention.'
Dallas Campbell, author of Ad Astra: An Illustrated Guide to
Leaving the Planet Cancer has always been with us. It killed our
hominid ancestors, the mammals they evolved from and the dinosaurs
that trampled the ground before that. Tumours grow in pets,
livestock and wild animals. Even tiny jelly-like Hydra - creatures
that are little more than a tube full of water - can get cancer.
Paradoxically, many of us think of cancer as a contemporary killer,
a disease of our own making caused by our modern lifestyles. But
that's not true. Although it might be rare in many species, cancer
is the enemy lurking within almost every living creature. Why?
Because cancer is a bug in the system of life. We get cancer
because we can't not get it. Cancer starts when cells revolt,
throwing off their molecular shackles, and growing and dividing out
of control in a shambolic mockery of normal life. This is why we
can't avoid cancer: because the very genes that drive it are
essential for life itself. The revolution has raged, on and off,
for millions of years. But it was only in the twentieth century
that doctors and scientists made any significant progress in
understanding and treating cancer, and it's only in the past few
decades that we've finally begun to kick the mob's malignant arse.
Now the game is changing. Scientists have infiltrated cancer's
cellular rebellion and are finally learning its secrets. Geneticist
and science writer Kat Arney takes the reader back to the dawn of
life on planet earth right up to the present day to get to the
heart of what cancer really is and how by better understanding it
we might one day overcome it.
The Compact Guide: DNA provides a fascinating look at the world of
the double helix and examines who we are, how we're wired, and how
we repair ourselves. With information on so-called 'junk' DNA, how
our genes evolved, heritability, the genetics of neuroscience,
viruses, disease and what happens when things go wrong, this is a
beautiful, visual journey through the polymer chain. The Compact
Guide: DNA is an engaging and essential read for anyone captivated
by the scope of human discovery, and reveals how we might just
uncover the answers to the secrets of life on Earth.
Why do we get cancer? Is it our modern diets and unhealthy habits?
Chemicals in the environment? An unwelcome genetic inheritance? Or
is it just bad luck? The answer is all of these and none of them.
We get cancer because we can't avoid it--it's a bug in the system
of life itself. Cancer exists in nearly every animal and has
afflicted humans as long as our species has walked the earth. In
Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest
Betrayal, Kat Arney reveals the secrets of our most formidable
medical enemy, most notably the fact that it isn't so much a
foreign invader as a double agent: cancer is hardwired into the
fundamental processes of life. New evidence shows that this disease
is the result of the same evolutionary changes that allowed us to
thrive. Evolution helped us outsmart our environment, and it helps
cancer outsmart its environment as well--alas, that environment is
us. Explaining why "everything we know about cancer is wrong,"
Arney, a geneticist and award-winning science writer, guides
readers with her trademark wit and clarity through the latest
research into the cellular mavericks that rebel against the rigid
biological "society" of the body and make a leap towards anarchy.
We need to be a lot smarter to defeat such a wily foe--smarter even
than Darwin himself. In this new world, where we know that every
cancer is unique and can evolve its way out of trouble, the old
models of treatment have reached their limits. But we are starting
to decipher cancer's secret evolutionary playbook, mapping the
landscapes in which these rogue cells survive, thrive, or die, and
using this knowledge to predict and confound cancer's next move.
Rebel Cell is a story about life and death, hope and hubris, nature
and nurture. It's about a new way of thinking about what this
disease really is and the role it plays in human life. Above all,
it's a story about where cancer came from, where it's going, and
how we can stop it.
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