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This volume explores immune cell receptors that are used in the
detection of microbes, either by binding directly to non-self
molecules or through indirectly sensing microbe-associated cellular
disturbances. The chapters in this book cover methods for studying
receptor-ligand interactions at both molecular and cellular levels;
methods to create and characterize novel antibody reagents; and
methods to characterize the molecular processes that lead to
adaptive receptor maturation. This book also contains chapters that
look at high-throughput strategies that describe the diversity of
immune receptors and cells. Written in the highly successful
Methods in Molecular Biology series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips on troubleshooting and avoiding
known pitfalls. Cutting-edge and authoritative, Immune Receptors:
Methods and Protocols, Second Edition is a valuable resource for
scientists and researchers interested in learning more about this
developing field.
This volume explores immune cell receptors that are used in the
detection of microbes, either by binding directly to non-self
molecules or through indirectly sensing microbe-associated cellular
disturbances. The chapters in this book cover methods for studying
receptor-ligand interactions at both molecular and cellular levels;
methods to create and characterize novel antibody reagents; and
methods to characterize the molecular processes that lead to
adaptive receptor maturation. This book also contains chapters that
look at high-throughput strategies that describe the diversity of
immune receptors and cells. Written in the highly successful
Methods in Molecular Biology series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips on troubleshooting and avoiding
known pitfalls. Cutting-edge and authoritative, Immune Receptors:
Methods and Protocols, Second Edition is a valuable resource for
scientists and researchers interested in learning more about this
developing field.
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