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This book describes how biologically available free energy sources
(ATP, chemical potential, and membrane potentials, among others)
can be used to drive synthetic reactions, signaling in cells, and
various types of motion such as membrane traffic, active transport,
and cell locomotion. As such, it approaches the concept of the
energy cycle of life on Earth from a physical point of view,
covering topics ranging from an introduction to chemical evolution,
to an examination of the catalytic activity of enzymes associated
with the genome in Darwinian evolution. The author introduces the
relationship between functions and physical properties in
biomembranes, explaining the methods and equipment used in
biophysics research to help researchers unravel the still-unsolved
mysteries of life. The physical principles needed to understand the
cellular functions are provided; these functions are associated
with biomembranes and regulated by physical properties of the lipid
bilayer such as membrane fluidity, phase transition, and phase
separation, as shown in lipid rafts. Other key dynamic aspects of
life (cell locomotion, cytoskeletal dynamics, and sensitivities of
the cell to physical stimuli such as external forces and
temperature) are also discussed. Lastly, readers will learn how
life on Earth and its ecological system are maintained by solar
energy, and be provided further information on the problems
accompanying global warming.
This book describes how biologically available free energy sources
(ATP, chemical potential, and membrane potentials, among others)
can be used to drive synthetic reactions, signaling in cells, and
various types of motion such as membrane traffic, active transport,
and cell locomotion. As such, it approaches the concept of the
energy cycle of life on Earth from a physical point of view,
covering topics ranging from an introduction to chemical evolution,
to an examination of the catalytic activity of enzymes associated
with the genome in Darwinian evolution. The author introduces the
relationship between functions and physical properties in
biomembranes, explaining the methods and equipment used in
biophysics research to help researchers unravel the still-unsolved
mysteries of life. The physical principles needed to understand the
cellular functions are provided; these functions are associated
with biomembranes and regulated by physical properties of the lipid
bilayer such as membrane fluidity, phase transition, and phase
separation, as shown in lipid rafts. Other key dynamic aspects of
life (cell locomotion, cytoskeletal dynamics, and sensitivities of
the cell to physical stimuli such as external forces and
temperature) are also discussed. Lastly, readers will learn how
life on Earth and its ecological system are maintained by solar
energy, and be provided further information on the problems
accompanying global warming.
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