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In 1961, neurobiologists found that the conduction velocity of the
nerve impulse in the giant nerve fiber of the" Penaeus "shrimp
abdominal nerve cord was over 200 m/s, the highest speed of
information transmission ever observed in the animal kingdom. The
peculiar myelin sheath with its unique nodal structure and the
electrical properties of the nerve fibers of the shrimp have
continued to be investigated for a quarter of century and are now
fully described in this book. The investigation dispels the
commonly held belief that the fastest recorded impulse conduction
is about 120 m/s in the thickest vertebrate myelinated nerve
fibers. In the shrimp, researchers found a completely novel type of
functional node in the giant fiber which they designated as the
fenestration node. In portions of the myelinated fiber, the
fenestration node furnished the sites of excitation. Also
discovered was a new strategy for increasing impulse conduction in
the shrimp. The book includes a section on the formation of the
fenestration node and the discovery of a strategy that allows the
shrimp to escape its predators by an action of the fastest
velocity. The data presented in this volume on the myelin sheath of
invertebrates present a new direction for this field and a rich
source of information for neurobiologists worldwide.
In 1961, neurobiologists found that the conduction velocity of the
nerve impulse in the giant nerve fiber of the Penaeus shrimp
abdominal nerve cord was over 200 m/s, the highest speed of
information transmission ever observed in the animal kingdom. The
peculiar myelin sheath with its unique nodal structure and the
electrical properties of the nerve fibers of the shrimp have
continued to be investigated for a quarter of century and are now
fully described in this book. The investigation dispels the
commonly held belief that the fastest recorded impulse conduction
is about 120 m/s in the thickest vertebrate myelinated nerve
fibers. In the shrimp, researchers found a completely novel type of
functional node in the giant fiber which they designated as the
fenestration node. In portions of the myelinated fiber, the
fenestration node furnished the sites of excitation. Also
discovered was a new strategy for increasing impulse conduction in
the shrimp. The book includes a section on the formation of the
fenestration node and the discovery of a strategy that allows the
shrimp to escape its predators by an action of the fastest
velocity. The data presented in this volume on the myelin sheath of
invertebrates present a new direction for this field and a rich
source of information for neurobiologists worldwide.
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Frontiers in Internet Technologies - Third CCF Internet Conference of China, ICoC 2014, Shanghai, China, July 10-11, 2014, Revised Selected Papers (Paperback, 2015 ed.)
Shiyong Zhang, Ke Xu, Mingwei Xu, Jie Wu, Chengrong Wu, …
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R1,801
R633
Discovery Miles 6 330
Save R1,168 (65%)
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Out of stock
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This book constitutes the refereed proceedings of the Third CCF
Internet Conference of China, ICoC 2014, held in Shanghai, China,
in July 2014. The 10 revised full papers presented were carefully
reviewed and selected from 94 submissions. The papers address
issues such as software defined network, network security, future
Internet architecture, Internet application, network management,
network protocols and models, wireless and sensor networks.
This brief guides the reader through three basic Internet resource
pricing models using an Internet cost analysis. Addressing the
evolution of service types, it presents several corresponding
mechanisms which can ensure pricing implementation and resource
allocation. The authors discuss utility optimization of network
pricing methods in economics and underline two classes of pricing
methods including system optimization and entities' strategic
optimization. The brief closes with two examples of the newly
proposed pricing strategy helping to solve the profit distribution
problem brought by P2P free-riding and improve the pricing
efficiency with the introduction of the price discrimination. The
Internet resource pricing strategy is not only the key factor of
Internet resource allocation efficiency, but also the determinant
of the profit. The methods and models discussed in Internet
Resource Pricing Models increase the efficiency of existing pricing
strategies to ensure a sound and sustainable development of the
Internet. The brief will help researchers and professionals working
with this key factor of Internet resource allocation.
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Blockchain Technology and Application - Third CCF China Blockchain Conference, CBCC 2020, Jinan, China, December 18-20, 2020, Revised Selected Papers (Paperback, 1st ed. 2021)
Ke Xu, Jianming Zhu, Xianhua Song, Zeguang Lu
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R1,495
Discovery Miles 14 950
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Out of stock
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This book constitutes the refereed proceedings of the Third CCF
China Blockchain Conference, CBCC 2020, held in Jinan, China,
December 2020. The 8 revised full papers presented were carefully
reviewed and selected from 64 submissions. The papers deal with
research results and development activities in all aspects of
blockchain science and technology.
PTEN (Phosphatase and Tensin Homolog) is a dual-specificity
phosphatase, and a member of the broad protein tyrosine phosphatase
family. PTEN gene encode a phosphatidylinositol-3,4,5-trisphosphate
3-phosphatase. It plays an important role in a variety of cellular
process including cell proliferation, cell differentiation, cell
migration and cell death. When the PTEN enzyme functions properly,
it acts as part of a pathway that signals cells to stop dividing
and can cause cells to undergo programmed cell death when
necessary. These functions prevent uncontrolled cell growth. When
the PTEN enzyme function is disrupted, it can lead to human
diseases, such as cancer, Cowden syndrome, chronic inflammatory
syndromes, developmental defect and diabetes. Especially in cancer,
PTEN is one of the most widely studied tumour suppresser genes. It
has been found to be the second most frequently mutated gene in
human cancers, second only to the tumour suppresser p53 gene. The
goal of this book is to provide a wide-ranging forum in the PTEN
research field, in particular, with a focus on the structure,
mechanism of action and role in cell signalling and regulation. The
authors contributing to this book, are all most active researchers
in PTEN research field. They presented the most recent advances,
approaches and future prospects on PTEN research. This book is
suitable as both a professional reference and as a text for
biological, medical, biomedical and pharmaceutical interest to
scientists, clinicians, teachers and students.
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