This book discusses fundamentals of Blockchain technology and Industry 4.0. It discusses many applications of Blockchain technology in Industry 4.0, including integration of AI, IoT, and big data with Blockchain for Industry 4.0. It provides cutting-edge research content from researchers, academicians, and other professionals from different background areas to show their state-of-the-art knowledge to use Blockchain in Industry 4.0. The book discusses advantages of Industry 4.0, such as improved productivity, improved efficiency, flexibility, agility, better user experience, and many more, and also entails some challenges too, such as trust, traceability, security, reliability, transparency, etc., for creating an application of Industry 4.0. The book helps graduate, postgraduate, doctoral students, and industrial professionals to implement Blockchain in Industry 4.0.