Fibroblast Growth Factor 23 describes how FGF23 was initially identified as a bone-derived factor targeting the kidney. As such, sections in this comprehensive book cover exciting research that shows that different FGF23 effects require distinct signaling receptors and mediators that differ among target tissues, cover FGF23 initially identified as a bone-derived factor targeting the kidney, look at FGF23 as a regulator of phosphate metabolism and beyond, and cover research on novel concepts of FGF receptor signaling. Additional sections cover biochemistry, pharmacology and nephrology, making this book an ideal reference source on FGF23.

In Still Seeing Red, John Kenneth White explores how the Cold War molded the internal politics of the United States. In a powerful narrative backed by a rich treasure trove of polling data, White takes the reader through the Cold War years, describing its effect in redrawing the electoral map as we came to know it after World War II. The primary beneficiaries of the altered landscape were reinvigorated Republicans who emerged after five successive defeats to tar the Democrats with the ?soft on communism? epithet. A new nationalist Republican party?whose Cold War prescription for winning the White House was copyrighted to Dwight Eisenhower, Richard M. Nixon, Barry Goldwater, and Ronald Reagan?attained primacy in presidential politics because of two contradictory impulses embedded in the American character: a fanatical preoccupation with communism and a robust liberalism. From 1952 to 1988 Republicans won the presidency seven times in ten tries. The rare Democratic victors?John F. Kennedy, Lyndon B. Johnson, and Jimmy Carter?attempted to rearm the Democratic party to fight the Cold War. Their collective failure says much about the politics of the period. Even so, the Republican dream of becoming a majority party became perverted as the Grand Old Party was recast into a top-down party routinely winning the presidency even as its electoral base remained relatively stagnant.In the post?Cold War era, Americans are coming to appreciate how the fifty-year struggle with the Soviet Union organized thinking in such diverse areas as civil rights, social welfare, education, and defense policy. At the same time, Americans are also more aware of how the Cold War shaped their lives?from the ?duck and cover? drills in the classrooms to the bomb shelters dug in the backyard when most Baby Boomers were growing up. Like millions of Baby Boomers, Bill Clinton can truthfully say, ?I am a child of the Cold War.?With the last gasp of the Soviet Union, Baby Boomers and others are learning t

This comprehensive examination of Soviet air power analyzes the three branches of the USSR Military Air Forces-Frontal Aviation, Long-Range Aviation, and Military Air Transport-and Naval Aviation and the National Air Defense, emphasizing World War II and postwar developments.

This comprehensive examination of Soviet air power analyzes the three branches of the USSR Military Air Forces & Frontal Aviation, Long-Range Aviation, and Military Air Transport and Naval Aviation and the National Air Defense, emphasizing World War II and postwar developments.

"Second Edition examines in detail the process of evaluating bridge conditions and offers a thorough study of bridge types - their origins, elements, and failures. Bridge Maintenance Inspection and Evaluation, Second Edition presents new and expanded information on condition ratings, capacity evaluations, load factor analysis, and the American Association of State Highway and Transportation Officials (AASHTO) suggested guidelines. "

In "Still Seeing Red, " John Kenneth White explores how the Cold War molded the internal politics of the United States. In a powerful narrative backed by a rich treasure trove of polling data, White takes the reader through the Cold War years, describing its effect in redrawing the electoral map as we came to know it after World War II. The primary beneficiaries of the altered landscape were reinvigorated Republicans who emerged after five successive defeats to tar the Democrats with the "soft on communism" epithet. A new nationalist Republican party--whose Cold War prescription for winning the White House was copyrighted to Dwight Eisenhower, Richard M. Nixon, Barry Goldwater, and Ronald Reagan--attained primacy in presidential politics because of two contradictory impulses embedded in the American character: a fanatical preoccupation with communism and a robust liberalism. From 1952 to 1988 Republicans won the presidency seven times in ten tries. The rare Democratic victors--John F. Kennedy, Lyndon B. Johnson, and Jimmy Carter--attempted to rearm the Democratic party to fight the Cold War. Their collective failure says much about the politics of the period. Even so, the Republican dream of becoming a majority party became perverted as the Grand Old Party was recast into a top-down party routinely winning the presidency even as its electoral base remained relatively stagnant.In the post-Cold War era, Americans are coming to appreciate how the fifty-year struggle with the Soviet Union organized thinking in such diverse areas as civil rights, social welfare, education, and defense policy. At the same time, Americans are also more aware of how the Cold War shaped their lives--from the "duck and cover" drills in the classrooms to the bomb shelters dug in the backyard when most Baby Boomers were growing up. Like millions of Baby Boomers, Bill Clinton can truthfully say, "I am a child of the Cold War."With the last gasp of the Soviet Union, Baby Boomers and others are learning that the politics of the Cold War are hard to shed. As the electoral maps are being redrawn once more in the Clinton years, landmarks left behind by the Cold War provide an important reference point. In the height of the Cold War, voters divided the world into "us" noncommunists versus "them" communists and reduced contests for the presidency into battles of which party would be tougher in dealing with the Evil Empire. But in a convoluted post-Cold War era, politics defies such simple characteristics and presidents find it harder to lead. Recalling how John F. Kennedy could so easily rally public opinion, an exasperated Bill Clinton once lamented, "Gosh, I miss the Cold War."

These three books reflect the beginnings of one of the most radical and exhilarating figures in modern literature Incandescent Limbo recounts White's years in Paris. Many a writer in the modern era had made Paris a focal point of his or her activity, but probably no one made more of it or got more out of it than Kenneth White. While exploring a labyrinthine underworld, the book is fundamentally an autoanalysis and traces the birth of the writer as an intellectual nomad. Letters from Gourgounel takes us from the city to a wild part of south-eastern France, the Ardeche, where White undertakes a resourcing in an elementary context. Hailed in England as a 'fascinating curiosity of literature', this book not only made White famous overnight in France, it was seen there as a turning point in the contemporary situation. In the third book, Travels in the Drifting Dawn, the intellectual nomad begins his moves across territories and cultures. After passing through the London underground of the sixties, then delving into the ground of his native Scotland and neighbouring Ireland, we shift back to the Continent, accumulating experience on different levels in France, Spain, Belgium, Holland, before concluding the cycle in North Africa. The trilogy is not only a summary of White's itinerary in its initial stages, it opens up a whole intellectual and cultural programme.

Three collections of essays whose aim is to express the cartography and the experience of a live, open world These essays all explore Scottish subjects and the wider issues of geopetics. This volume starts with On Scottish Ground by delving into forgotten cultural resources. Ideas of Order at Cape Wrath explores more socio-political considerations before opening out to a larger space of cosmological meditation in The Wanderer and his Charts.

These three books reflect the beginnings of one of the most radical and exhilarating figures in modern literature Incandescent Limbo recounts White's years in Paris. Many a writer in the modern era had made Paris a focal point of his or her activity, but probably no one made more of it or got more out of it than Kenneth White. While exploring a labyrinthine underworld, the book is fundamentally an autoanalysis and traces the birth of the writer as an intellectual nomad. Letters from Gourgounel takes us from the city to a wild part of south-eastern France, the Ardeche, where White undertakes a resourcing in an elementary context. Hailed in England as a 'fascinating curiosity of literature', this book not only made White famous overnight in France, it was seen there as a turning point in the contemporary situation. In the third book, Travels in the Drifting Dawn, the intellectual nomad begins his moves across territories and cultures. After passing through the London underground of the sixties, then delving into the ground of his native Scotland and neighbouring Ireland, we shift back to the Continent, accumulating experience on different levels in France, Spain, Belgium, Holland, before concluding the cycle in North Africa. The trilogy is not only a summary of White's itinerary in its initial stages, it opens up a whole intellectual and cultural programme.

Three collections of essays whose aim is to express the cartography and the experience of a live, open world These essays all explore Scottish subjects and the wider issues of geopetics. This volume starts with On Scottish Ground by delving into forgotten cultural resources. Ideas of Order at Cape Wrath explores more socio-political considerations before opening out to a larger space of cosmological meditation in The Wanderer and his Charts.

The Scottish poet Kenneth White and the Australian philosopher Jeff Malpas came together by chance when Malpas heard an interview with White on ABC radio. Malpas contacted White, and from there they exchanged books and ideas. They arranged to meet at White's place on the Breton coast, where a conversation about poetry and philosophy developed over four days. Inspired by poets from John Donne to Hoelderlin, and philosophers from Nietzsche to Heidegger, they discussed the world, place, narrative, language and politics. This book records that conversation. The Fundamental Field is made up of two essays: the first is by White on Malpas; the second is by Malpas on White. The volume closes with a set of three new philosophical poems by White.

The Scottish poet Kenneth White and the Australian philosopher Jeff Malpas came together by chance when Malpas heard an interview with White on ABC radio. Malpas contacted White, and from there they exchanged books and ideas. They arranged to meet at White's place on the Breton coast, where a conversation about poetry and philosophy developed over four days. Inspired by poets from John Donne to Hoelderlin, and philosophers from Nietzsche to Heidegger, they discussed the world, place, narrative, language and politics. This book records that conversation. The Fundamental Field is made up of two essays: the first is by White on Malpas; the second is by Malpas on White. The volume closes with a set of three new philosophical poems by White.

American Political Parties is a core textbook on political parties in the United States that places the US party system into a framework designed around the disagreements between Alexander Hamilton and Thomas Jefferson. White and Kerbel argue that the two-party system in the United States began with a common agreement on the key values of freedom, individual rights, and equality of opportunity but that Hamilton and Jefferson disagreed-often vehemently-over how to translate these ideals into an acceptable form of governance. This text develops a unique historical perspective of US party development using the disagreements between Alexander Hamilton and Thomas Jefferson as a framework for analysis. While Hamilton wanted to marry freedom to a strong, active federal government with an energetic president who would act on behalf of all citizens, Jefferson believed that freedom should be allied to local civic virtue, with governmental responsibilities placed primarily at the local level. Today, Hamiltonian nationalism finds its home in the Democratic Party, while Republicans have espoused Jeffersonian localism since 1964. Using this historical framework, American Political Parties examines a range of topics including marketing and social media, campaign finance, reforms in the presidential nominating process, political demography, and third parties. In this new edition (previously published as Party On!), the authors describe four possible futures in the wake of the 2020 election and why Americans believed it was "the most important" election in their lifetimes. The unique history of US political parties as set forth by the disagreements between Alexander Hamilton and Thomas Jefferson is at an inflection point. Republicans have become an insurgent party fully under the control of Donald Trump while Democrats have an opportunity to create a new majority coalition. This juncture poses unique challenges to our democracy and constitutional framework, and the book describes four possible outcomes, postulating where American political parties are headed in this decade.

In choosing candidates for political office, values (both those held by voters and those of prospective officeholders) have overtaken economics to become key determinants in the voting choice. Since the 1960s the American public has wrestled with changes in public and private values. Typical family life no longer involves a husband, a wife, and the prototypical two children. The idealized Cleaver, Nelson, and Huxtable families once portrayed on television now mirror a minority of the American electorate. "The Values Divide," John White's fascinating new book, explores the increasingly dominant role values play in today's public and private life, concluding that a serious rift in political and cultural values actually produced the astounding tie between George W. Bush and Al Gore in the 2000 presidential election. White argues that while politically important, the present values "divide" goes much deeper than cultural conflicts between Republicans and Democrats. Today, citizens are reexamining their own intimate values including how they work, live, and interact with each other in a country whose population is rapidly changing. Collectively, the answers to these value questions have remade both American politics and the popular culture. Reflecting upon these divergent personal choices, White concludes that one further question remains: "What does it mean to be an American?" Features: Compiles extensive current public opinion polling data from The Roper Center at the University of Connecticut at key moments in recent American history including during the Columbine tragedy, the Clinton-Lewinsky scandal, Clinton's impeachment, and the Election of 2000 to present a snapshot of American valuesas we enter the 21st century. Provides a compelling explanation for the outcome of Election 2000 and the prospects for the Republican and Democratic political agenda over the long-term.