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This volume contains the proceedings of the latest in a series of
international symposia on advances in neuro-oncology, held
September 26-29, 1990, in San Remo, Italy and sponsored by the
University of Pavia, I.R.C.C.S. Policlinico San Matteo (Pavia,
Italy) and the Giovanni Lorenzini Medical Foundation
(Milan-Houston). It drew papers from six continents of the world,
was attended by over 500 investigators, and demonstrated the
extraordinary vitality, depth and breadth of research which
characterizes modem neuro-oncology. Over the course of the last
decade, there has been a remarkable shift in research carried out
in the heterogeneous field of neuro-oncology, which appears to be
away from clinical descriptive studies, and toward more basic and
fundamental investigation of the pathology, immunohis tochemistry,
biochemical and cellular subsets of brain tumors. Besides the
traditional fields of neurology, neurosurgery, neuropathology, and
radiation therapy, there has been an increased interest and
involvement by investigators in the fields of medical oncology,
neuroradiology, immunology, and many areas of fundamental
neurobiology. It has become evident that interest has also been
exhibited in a broader spectrum of tumors than just the malignant
glial series, and studies in meningioma, craniopharyngioma,
neurinomas, and the pituitary tumors were reported. Several
sessions were devoted to the special problems of pediatric brain
tumors."
The first international symposium on brain edema was held in
Vienna/ Austria in 1965 followed by altogether eight meetings
since. The most recent was organized in Y okohama by the Department
of Neurosurgery of the Musashino Red Cross Hospital, Tokyo. The
continuing interest of both, clinicians and experimental scientists
alike may be attributable to the fact that brain edema is a common
denominator of many cerebral disorders, which under acute
conditions threatens life and weIl-being of afflicted patients.
Although progress in understanding as weIl as treatment can be
recognized since 1965 many problems remain, particularly concerning
the control of brain edema under acute conditions, as in trauma or
ischemia. A quantum leap was the distinction of the cytotoxic and
vasogenic brain edema prototypes as advanced by Igor Klatzo,
providing for transition from a morphological to functional
understanding now. The recent brain edema meetings were certainly
benefiting from developments of both, molecular neurobiology on the
one hand side and functional brain imaging at an ever-increasing
resolution on the other, such as magnetic resonance imaging
orpositron emission tomography. The international symposium in San
Diego 1996 may witness further breakthroughs, hopefully also of
effective treatment modalities. The symposium in Y okohama was
dedicated to the "Legacy of 28 Years of Brain Edema Research" as a
reminder of accomplishments as weIl as remaining challenges.
The articles in this volume cover the various options of the
optimal management of brain tumors, vascular lesions, and
functional disorders. They provide a good balance between
microneurosurgery and radiosurgery, presenting also alternative
surgical and radiosurgical treatment options with discussions on
their advantages and disadvantages. The presentation of multiple
treatment methods will help to provide better service to patients.
Some papers, specifically highlighting alternative treatment
options, are accompanied by editorials prepared by recognized
experts in the field. Additional emphasis is put on importance of
the advanced neuroimaging techniques for radiosurgical treatment
planning and subsequent follow-up.
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Neuro-Oncology (Hardcover)
P. Paoletti, Kintomo Takakura, M.D. Walker, G. Butti, S. Pezzotta
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R3,281
Discovery Miles 32 810
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Ships in 10 - 15 working days
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This volume focuses on the present state of biological research as
well as the diagnosis and treatment of nervous system neoplasia.
The section concerning 'Biology and Diagnosis' describes the aspect
related to brain tumour classification and neuro-radiological
diagnosis. Papers on oncogenes and growth factor expression are
also included. The role of surgery, radiotherapy and chemotherapy,
as well as new therapeutic approaches, is described in the section
on 'Therapy of Gliomas'. "Neuro-Oncology" presents an up-to-date
review of research on biological studies and the treatment of
meningiomas, neuronomas, craniopharingiomas, pinealomas, metastatic
tumours, and cerebral tumours in children written by some of the
most respected neurosurgeons in the world. The book is recommended
not only to neurosurgeons and neurologists, but also to all
researchers actively working in the field of neuro-oncology.
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