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You see things, and sa)' why? But I dream 1hings that never were,
and I say, 11'hy 110t? George Bernhard Shaw Far ahead of his time,
June 1st, 1909, Alexander Maximov communicated in a lecture, given
in the Charite in Berlin, the fundamental knowledge, that there
exists a lymphoid hemopoetic stem cell. Alexander Friedenstein
explained that during the following years, Maximov also showed that
the idea of interaction between hemopoetic cells and their stroma
to be one of the most significant experiences. Monoclonal
antibodies, recombinant DNA technics and the improvement of tissue
culture models are the major developments to improve our
possibilities to clarify growth and differentiation functions of
hemopoetic cells. During the last two decades it was shown that
soluble products, released from T cells, were not only involved in
inducing B cells to produce specific immunoglobulin secretion after
antigen stimulation. Furthermore, lymphokines together with other
cytokines regulate the growth and differentiation of hemopoetic
cells. As I have learned from Dick Gershon, our knowledge of the
cellular basis for immunoregulation has come a long way since 450
B.C. Thucydides comments on the possible role of immune response in
controlling the Black Death. Dick Gershon speculated that no
scientific interest for these interesting observations was put
forth at that time. Perhaps the problems, the Athenians were having
with the Spartans, converted money from basis research into the
military budget.
Gut ist eine Lehrart, wo man vom Bekannten zum Unbekannten
fortschreitet; schon ist sie, wenn sie sokratisch ist, d.i. wenn
sie dieselben Wahrheiten aus dem Kopf und Herzen des Zuhorers
herausfragt. Bei der ersten werden dem Verstand seine Uberzeugungen
in Form abgefordert, bei der zweiten sie ihm abgelockt. Professor
Friederich Schiller Jena, in a letter written on 23 February 1793
to his friend and supporter Korner, father of the poet Theodor
Korner. Established clinicians and scientists as weil as students
aga in tried the Wilsede experiment for three days and nights and
learned from each other. In our fourth Wilsede meeting on "Modern
Trends in Human Leukemia" we concentrated once again on questions
re gar ding the practical application of research and its benefits
to the patient. The main emphasis of leukemia research has changed
since the first Wilsede meeting in 1973. Virology is no longer the
sole interest. Advances in immunology and cell genetics and a
better understanding of Dr. h. c. Alfred Toepfer speeking with
participants of the meeting in Wilsede XXI Arrival and discussion
of participants in front of the meeting pI ace "De Emmenhoff" XXII
Personal and scientific discussion in Wilsede June 1980 Fotos: R.
Vols XXIII the mechanisms regulating normal and pathological blood
cell differen tiation have had a considerable impact on the
direction of leukemia research."
mene Stil in jeglicher Kunst, daft er die spezijischen Schranken
derselben zu entfernen weip, ohne doch ihre spezijischen Vorzuge
mit aufzuhe- ben, und durch eine weise Benut- zung ihrer
Eigentumlichkeit ihr einen mehr allgemeinen Charakter erteilt.
Friedrich Schiller - Ober die as the- tische Erziehung des
Menschen. In den Horen, 22. Brief (1795) We are glad that you have
all come to this small village and I hope that you will feel at
home here for the next few days. The special atmosphere of the
surround- ings will probably have a good influence on our
discussions, and you will perhaps remember this when you are back
home again. It takes hard work to save this little piece of nature
for man in our highly industrialized world, and we should all be
grateful to the Verein Naturschutzpark e. V. (founded in 1909),
Alfred Toepfer and his associates for their efforts. We intend to
discuss modern trends in human leukemia in this workshop, but we
should also take the opportunity to reflect on the trends of the
past, which might still be modern.
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