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This volume focuses on solution and solid-state NMR of
carbohydrates, glycoproteins, glyco-technologies, biomass and
related topics. It is estimated that at least 80% of all proteins
are glycoproteins. Because of the complexity, heterogeneity and
flexibility of the sugar chains, the structural biology approaches
for glycoconjugates have been generally avoided. NMR techniques
although well established for structural analyses of proteins and
nucleic acids, cannot be simply applied to this complex class of
biomolecules. Nonetheless, recently developed NMR techniques for
carbohydrates open the door to conformational studies of a variety
of sugar chains of biological interest. NMR studies on glycans will
have significant impact on the development of vaccines, adjuvants,
therapeutics, biomarkers and on biomass regeneration. In this
volume, the Editors have collected the most up-to-date NMR
applications from experts in the field of carbohydrate NMR
spectroscopy. Timely and useful, not only for NMR specialists, it
will appeal to researchers in the general field of structural
biology, biochemistry and biophysics, molecular and cellular
biology and material science.
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