This book brings together about 2,500 quotations on various topics of interest to scientists and engineers, including students of STEM disciplines. Careful curation of the material by the editor provides the reader with far greater value than can be obtained by searching the internet. The quotes have been selected for various attributes including: importance of topic, depth of insight, and - not least - wit, with many of them satisfying all these criteria. To make sequential reading of the quotes more engaging, they are grouped into broad topical sections, and the entries within each section are organized thematically, forming quasi-continuous narrative threads. The text and authorship of each quote have been carefully verified, and the most popular cases of misquotation and misattribution are noted. The book represents a valuable resource for those writing science and engineering articles as well as being a joy to read in its own right.