This book constitutes the proceedings of the International Summit on Electronic Healthcare, eHealth 360 Degrees, held in Budapest, Hungary, in June 2016. The 55 revised full papers presented along with 9 short papers were carefully reviewed and selected from 81 submissions. The papers represent the latest results from the co-located conferences as the track on games for wellbeing, the track on wearables in healthcare, the track on personal, pervasive and mobile health, the track on IoT and big data technologies for healthcare, the track on mobile medical multimedia technologies, applications and services and the track on ambient assisted living technologies based on IoT.