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The NATO Advanced Research Workshop (ARW) on "Regulation of
Enzymatic Systems Detoxifying Xenobiotics in Plants" intended to
provide a forum to scientists from academia, industry, and
govemment for discussing and critically assessing recent advances
in the field of xenobiotic metabolism in plants and for identifying
new directions for future research. Plants function in a chemical
environment made up of nutrients and xenobiotics. Xenobiotics
(foreign chemicals) are natural or synthetic compounds that can not
be utilized by plants for energy-yielding metabolism. Plants may be
exposed to xenobiotics either deliberately, due to their use as
pesticides or accidentally, from industrial, agricultural, and
other uses. Plants, like most other organisms, evolved a remarkable
battery or metabolic reactions to defend themselves against the
potentially toxic effects of xenobiotics. The main enzymatic
reactions utilized by plants for xenobiotic detoxification include
oxidation, reduction, hydrolysis and conjugation with glutathione,
sugars (e.g., glucose), and amino acids. Eventually, xenobiotic
conjugates are converted to insoluble bound residues or to
secondary conjugates, which are deposited in the vacuole of plant
cells.
The NATO Advanced Research Workshop (ARW) on "Regulation of
Enzymatic Systems Detoxifying Xenobiotics in Plants" intended to
provide a forum to scientists from academia, industry, and
govemment for discussing and critically assessing recent advances
in the field of xenobiotic metabolism in plants and for identifying
new directions for future research. Plants function in a chemical
environment made up of nutrients and xenobiotics. Xenobiotics
(foreign chemicals) are natural or synthetic compounds that can not
be utilized by plants for energy-yielding metabolism. Plants may be
exposed to xenobiotics either deliberately, due to their use as
pesticides or accidentally, from industrial, agricultural, and
other uses. Plants, like most other organisms, evolved a remarkable
battery or metabolic reactions to defend themselves against the
potentially toxic effects of xenobiotics. The main enzymatic
reactions utilized by plants for xenobiotic detoxification include
oxidation, reduction, hydrolysis and conjugation with glutathione,
sugars (e.g., glucose), and amino acids. Eventually, xenobiotic
conjugates are converted to insoluble bound residues or to
secondary conjugates, which are deposited in the vacuole of plant
cells.
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