As the First International Conference on Water and Ions in Biological Systems (Bucharest, June 25-27, 1980) was appreciated as a success, a second one was organized in the fall of the year 1982 under the sponsorship of the United Nations Educational, Scientific and Cultural Organization (UNESCO), the Romanian Academy of Medical Sciences, the Romanian Biophysical Society (Union of Societies for Medical Sciences in the Socialist Republic of Romania) and in co operation with the International Union for Pure and Applied Bio physics (IUPAB). The responsibility for the scientific program and organization of the Second Conference on Water fell on an International Scientific Committee which included Prof. J. Tigyi (Pees), President of the UNESCO Expert Committee on Biophysics, Prof. K. Wuthrich, Secretary General of IUPAB and Prof. H. Eisenberg, (member of the IUPAB Council) under the guidance of an Executive Board whose members were Prof. J. Jaz (representative of UNESCO), Prof. B. Pullman (Vice President of IUPAB) and Prof. V. Vasilescu (President of the Romanian Biophysical Society). The Meeting was attended by more than 250 specialists including 150 Romanian participants and others from Bulgaria, Czechoslovakia, England, the Federal Republic of Germany, the German Democratic Republic, Greece, Hungary, India, Israel, Italy, Japan, the Netherlands, Nigeria, Poland, Sweden, Switzerland, USSR, USA, Venezuela, Yugoslavia. The proceedings of the Conference took place in the Medical Faculty of Bucharest. The theoretical and practical importance of the Meeting was pointed out by the speakers, among whom were Prof."

As the First International Conference on Water and Ions in Biological Systems (Bucharest, June 25-27, 1980) was appreciated as a success, a second one was organized in the fall of the year 1982 under the sponsorship of the United Nations Educational, Scientific and Cultural Organization (UNESCO), the Romanian Academy of Medical Sciences, the Romanian Biophysical Society (Union of Societies for Medical Sciences in the Socialist Republic of Romania) and in co operation with the International Union for Pure and Applied Bio physics (IUPAB). The responsibility for the scientific program and organization of the Second Conference on Water fell on an International Scientific Committee which included Prof. J. Tigyi (Pees), President of the UNESCO Expert Committee on Biophysics, Prof. K. Wuthrich, Secretary General of IUPAB and Prof. H. Eisenberg, (member of the IUPAB Council) under the guidance of an Executive Board whose members were Prof. J. Jaz (representative of UNESCO), Prof. B. Pullman (Vice President of IUPAB) and Prof. V. Vasilescu (President of the Romanian Biophysical Society). The Meeting was attended by more than 250 specialists including 150 Romanian participants and others from Bulgaria, Czechoslovakia, England, the Federal Republic of Germany, the German Democratic Republic, Greece, Hungary, India, Israel, Italy, Japan, the Netherlands, Nigeria, Poland, Sweden, Switzerland, USSR, USA, Venezuela, Yugoslavia. The proceedings of the Conference took place in the Medical Faculty of Bucharest. The theoretical and practical importance of the Meeting was pointed out by the speakers, among whom were Prof.

Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age related disease and dysfunction. Much of this growth in the traditionally separate sciences of chemistry and molecular gerontology occurred independently, with little interaction or communi cation between the scientists working in these two fields. In view of the growing maturity of the two fields and the potential importance of advancing our knowledge in the area of oxidative stress and aging, we perceived a critical need to organize an international conference the "First Inter national Conference on Oxidative Stress and Aging" in Hawaii in 1994 to bring together the world's leading scientists in the fields of reactive oxygen species and molecular gerontology. The objective of this conference was to provide a unique opportunity for scholars working in these two related and rapidly growing fields to participate in the exchange, integration, and synthesis of new concepts and ideas, to engage in constructive criticism and to initiate new collaborative research projects. The conference focused on the molecular and cellular aspects of aging as related to oxidative stress. It was one of the largest and most comprehensive international conferences held in molecular gerontology. At this conference a call was made for submission of papers to be used in the publication of a book covering the major contributions of the meeting."

A NATO Advanced study Institute on "Receptors, Membrane Trans port and Signal Transduction", was held on the Island of Spet sai, Greece, from August 16-27, 1988, in order to consider re cent developments in membrane receptor research, membrane trans port and signal transduction mechanisms. These topics were put in the larger context of current knowledge on the structure and function of membranes; connections between different fields of research were established by in-depth dis cussions of energy transduction and transport mechanisms. The general principles of regulation by signal transduction and protein phosphorylation/dephosphorylation were presented in the context of specific cellular processes. Discussions included al so the role of protein tyrosine kinases which are structurally related to oncogene products and, therefore, implicated in va rious aspects of cell development and transformation. This book presents the content of the major lectures and a se lection of the most relevant posters presented during the course of the Institute. The book is intended to make the proceedings of the Institute accessible to a larger audience and to offer a comprehensive account of those topics on receptors, membrane transport and signal transduction that were discussed extensive ly during the course of the Institute. February 1989 The Editors CONTENTS I. G-PROTEINS, ADENYLATE CYCLASE AND PROTEIN PHOSPHORYLATION Selective regulation of G proteins by Cell surface receptors ......... .

The argument of this book begins with the proposition that there are certain things we must understand about the criminal sanction before we can begin to talk sensibly about its limits. First, we need to ask some questions about the rationale of the criminal sanction. What are we trying to do by defining conduct as criminal and punishing people who commit crimes? To what extent are we justified in thinking that we can or ought to do what we are trying to do? Is it possible to construct an acceptable rationale for the criminal sanction enabling us to deal with the argument that it is itself an unethical use of social power? And if it is possible, what implications does that rationale have for the kind of conceptual creature that the criminal law is? Questions of this order make up Part I of the book, which is essentially an extended essay on the nature and justification of the criminal sanction.
We also need to understand, so the argument continues, the characteristic processes through which the criminal sanction operates. What do the rules of the game tell us about what the state may and may not do to apprehend, charge, convict, and dispose of persons suspected of committing crimes? Here, too, there is great controversy between two groups who have quite different views, or models, of what the criminal process is all about. There are people who see the criminal process as essentially devoted to values of efficiency in the suppression of crime. There are others who see those values as subordinate to the protection of the individual in his confrontation with the state. A severe struggle over these conflicting values has been going on in the courts of this country for the last decade or more. How that struggle is to be resolved is a second major consideration that we need to take into account before tackling the question of the limits of the criminal sanction. These problems of process are examined in Part II.
Part III deals directly with the central problem of defining criteria for limiting the reach of the criminal sanction. Given the constraints of rationale and process examined in Parts I and II, it argues that we have over-relied on the criminal sanction and that we had better start thinking in a systematic way about how to adjust our commitments to our capacities, both moral and operational.

For serious followers of Jesus Christ, Lent is an opportunity to confront our own selfish tendencies and to humble ourselves before God. Since the 7th Century Christians have discovered real spiritual benefit as they have observed a season of spiritual emphasis before Easter - a 40 day fast over six weeks from Ash Wednesday to Easter. This book is a devotional guide based on the Sermon on the Mount to help believers examine themselves and to deepen in their love and commitment for Christ. Despite persecution in many places on the globe, Christians today have a greater share of this world's wealth than previous generations. Wise believers have always been more concerned about the pollution of the church by the world from within, than the threats against the church from without. Materialism, pride, and self-centeredness are issues that every generation of Christ-followers must address - this is where the real spiritual battle takes place. This devotional guide is personal and introspective, guiding the believer to examine himself against the biblical standard, and to re-focus his life on Christ. It is a celebration of the Savior's constant love and mercy that forgives our sins, cleanses us within, lifts us up and draws us to His face and His heart. Dr David Packer is from American originally but he has lived most of his adult life outside the United States. He holds a Doctor of Ministry from Southwestern Baptist Theological Seminary in Fort Worth, Texas, with a specialization in World Missions. He and his wife have lived and served in missionary and cross-cultural work in Asia and Europe. Previously, from 1992-2004 he served as Senior Pastor of the International Baptist Church of Singapore and currently he is Senior Pastor of the International Baptist Church of Stuttgart, Germany - a spiritual home to people from more than 40 nationalities. Together they have personally ministered in more than thirty different nations, and in 2009 they founded International Churches Ministry, Inc, a US-based legal charity to address the needs of international churches around the world. They have three grown children and two grandchildren...so far.

"Radiofrequency Catheter Ablation of Cardiac Arrhythmias" has been so extensively updated for its third edition that the book now features a new title: "Catheter Ablation of Cardiac Arrhythmias: Basic Concepts and Clinical Applications." The editors bring you 21 polished chapters, each updating the fundamentals and progressing to advanced concepts, providing state-of-the-art knowledge with highly relevant material for experienced electrophysiologists as well as fellows in training.

This streamlined new edition features:
- Two new editors, both widely published and leaders in the field of catheter ablation
- 21 instead of 39 chapters, achieved by focusing on primary topics of broad interest and assimilating information from a wide range of sources
- Fewer authors, chosen for their recognized contributions to the topics under discussion, providing a more integrated and coherent approach
- Anatomic insights from leading pathologist Siew Yen Ho, integrated with new information from imaging technologies

Each chapter dealing with ablation of a specific arrhythmia features the author's personal approach to ablation of the arrhythmia, including practical "how-to" tips, and a review of potential pitfalls. Alternate approaches and variations are succinctly summarized. Original figures and drawings illustrate specific approaches to improve the usability of the book.

The essays in this book, first published in 1860, were developed from a series of lectures on "The Conduct of Life" delivered by Emerson during the early 1850s. Some of the original lectures were dropped and the rest were considerably revised, with new topics introduced. The published essays, on "Fate," "Power," "Wealth," "Culture," "Behavior," "Worship," "Considerations by the Way," "Beauty," and "Illusions," show Emerson's interest in many practical aspects of human life, and reflect his increasing involvement in politics--chiefly in the antislavery movement--during the decade before the Civil War. This edition is based on Emerson's holograph manuscripts and published sources. The text incorporates Emerson's later corrections and revisions, and shows us what he actually wrote (or, perhaps in some cases, intended to write). The historical introduction traces the book's development and its relation to Emerson's own personal growth and political awareness. Joseph Slater's explanatory notes help the modern reader to understand many of Emerson's references and allusions that may not be readily apparent. Historical Introduction by Barbara L. Packer Notes by Joseph Slater Text Established and Textual Introduction and Apparatus by Douglas Emory Wilson

Barbara L. Packer's long essay ""The Transcendentalists"" is widely acknowledged by scholars of nineteenth-century American literary history as the best-written, most comprehensive treatment to date of Transcendentalism. Previously existing only as part of a volume in the magisterial ""Cambridge History of American Literature"", it will now be available for the first time in a stand-alone edition. Packer presents Transcendentalism as a living movement, evolving out of such origins as New England Unitarianism and finding early inspiration in European Romanticism. Transcendentalism changed religious beliefs, philosophical ideas, literary styles, and political allegiances. In addition, it was a social movement whose members collaborated on projects and formed close personal ties. Transcendentalism contains vigorous thought and expression throughout, says Packer; only a study of the entire movement can explain its continuing sway over American thought. Through fresh readings of both the essential Transcendentalist texts and the best current scholarship, Packer conveys the movement's genuine expectations that its radical spirituality not only would lead to personal perfection but also would inspire solutions to such national problems as slavery and disfranchisement. Here is Transcendentalism in whole, with Emerson, Thoreau, and Fuller restored to their place alongside such contemporaries as Bronson Alcott, George Ripley, Jones Very, Theodore Parker, James Freeman Clarke, Orestes Brownson, and Frederick Henry Hedge.