The exploration of the subnuclear world is done through increasingly complex experiments covering a wide range of energy and performed in a large variety of environments ranging from particle accelerators, underground detectors to satellites and the space laboratory. The achievement of these research programs calls for novel techniques, new materials and instrumentation to be used in detectors, often of large scale. Therefore, fundamental physics is at the forefront of technological advance and also leads to many applications. Among these, are the progresses from space experiments whose results allow the understanding of the cosmic environment, of the origin and evolution of the universe after the Big Bang.

The exploration of the subnuclear world is done through increasingly complex experiments covering a wide range of energy and performed in a large variety of environments ranging from particle accelerators, underground detectors to satellites and the space laboratory. Among recent advances one has to indicate, for instance, first results obtained from space and LHC experiments and progress done in preparation of the latter experiments upgrades, including plans for the LHC machine upgrade. The achievement of these research programs calls for novel techniques, new materials and instrumentation to be used in detectors, often of large scale. Therefore, fundamental physics is at the forefront of technological advance and also leads to many applications. Among these, medical applications have a particular importance due to health and social benefits they bring to the public.

The exploration of the subnuclear world is done through increasingly complex experiments covering a wide range of energies and in a large variety of environments - from particle accelerators and underground detectors to satellites and space laboratories. For these research programs to succeed, novel techniques, new materials and new instrumentation need to be used in detectors, often on a large scale. Hence, particle physics is at the forefront of technological advancement and leads to numerous applications. Among these, medical applications have a particular importance due to the health and social benefits they bring. This volume reviews the advances made in all technological aspects of current experiments in the field.