In this issue of Critical Care Clinics, guest editors Drs. Lauren R. Sorce and Joy D. Howell bring their considerable expertise to the topic of Pediatric Critical Care. Top experts in the field cover key topics such as point-of-care ultrasound for pediatric critical care providers; transfusion strategies in the 21st century; global pediatric critical care; workforce diversity; and more. Contains 13 relevant, practice-oriented topics including pediatric redeployment: unique challenges created by COVID-19; ECMO then and now; PCCM in 21st century and beyond; pediatric critical care outcomes; cardiac output monitoring; and more. Provides in-depth clinical reviews on pediatric critical care, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.