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Mouse Genetics offers for the first time in a single comprehensive volume a practical guide to mouse breeding and genetics. Nearly all human genes are present in the mouse genome, making it an ideal organism for genetic analyses of both normal and abnormal aspects of human biology. Written as a convenient reference, this book provides a complete description of the laboratory mouse, the tools used in analysis, and procedures for carrying out genetic studies, along with background material and statistical information for use in ongoing data analysis. It thus serves two purposes, first to provide students with an introduction to the mouse as a model system for genetic analysis, and to give practicing scientists a detailed guide for performing breeding studies and interepreting experimental results. All topics are developed completely, with full explanations of critical concepts in genetics and molecular biology. As investigators around the world are rediscovering both the heuristic and practical value of the mouse genome, the demand for a succinct introduction to the subject has never been greater. Mouse Genetics is intended to meet the needs of this wide audience.
Remaking Eden is a fascinating exploration of the future of reprogenetic technologies - a cautiously optimistic look at the scientific advances that will allow us to engineer life in ways that were unimaginable just a few short years ago. Indeed, in ways that go far beyond cloning, and that are at once more thrilling and more frightening. Could a woman give birth to her identical twin sister? Could a child have two genetic mothers? Could a man become pregnant? Could parents choose not only the physical characteristics of their children-to-be, but personalities and talents as well? Will genetic enhancement ultimately change the very nature of our species? The answers will excite some and alarm others. Silver demystifies the science involved in all these possibilities, calmly and efficiently dismantling our preconceptions and misconceptions. Throughout, he examines the profound ethical questions raised by these new technologies. Yet he reminds us that the desire both to have children and to provide them with all possible advantages in life is a uniquely powerful force - a force, he suggests, that will overcome all political and societal attempts to curb the use of reprogenetics.
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