Cells are the basis of all life in the universe. Our bodies are made up of billions of them: an incredibly complex society that governs everything, from movement to memory and imagination. When we age, it is because our cells slow down; when we get ill, it is because our cells mutate or stop working. In How We Live and Why we Die, Wolpert provides a clear explanation of the science that underpins our lives. He explains how our bodies function and how we derived from a single cell - the embryo. He examines the science behind the topics that are much discussed but rarely understood - stem-cell research, cloning, DNA - and explains how all life evolved from just one cell. Lively and passionate, How We Live and Why we Die is an accessible guide to understanding the human body and, essentially, life itself.

How does a single cell develop into myriad different specialised cell types, control the organization of these different cells into tissues and organs, and ultimately form an unimaginably complex living organism such as a human? Furthermore, how is it possible for some adult animals, but not others, to regenerate fully functioning limbs? Principles of Development opens up the fascinating field of developmental biology to those wanting to understand the answers to questions such as these. Cutting edge science is explained clearly and succinctly and is richly illustrated with a variety of custom drawn figures, animations, and links to online movies that show development happening in real time. The emphasis throughout the text is always on the key principles of development - the underlying processes shared by diverse groups of organisms. This focus on principles provides a framework on which a richer understanding of specific topics can be built. Moreover, extensive pedagogical support is provided, both in the book and online, making this text the complete package for those studying developmental biology. Online Resources For students: -Test your understanding with multiple choice questions and answer guidance to long-answer questions from the book -Gain a three dimensional perspective of development by watching the movies of developing model organisms -View the signalling pathway animations to see these complex processes broken down step by step -Expand your knowledge and guide your studies with the suggested web activities - Examine and interpret raw data obtained by Cheryll Tickle and members of her laboratory and presented in silico For registered adopters of the text: -Download the figures from the book to use in lectures and hand-outs -Help your students delve into the research literature with the Journal Club -Download the test bank or import it into your VLE -PowerPoint of In silico practicals to use in class

Why are there two sexes? How different are they and why? Why can't a woman be more like a man? Or should the question be: why can't a man be more like a woman? Controversy rages around sex and gender, but just what are the differences and how are they determined? Lewis Wolpert, distinguished scientist, broadcaster and author, has tackled depression, religion and old age from a developmental biologist's perspective. Now he enters the gender debate, starting with his argument that men are fundamentally modified females - if the genes present at fertilisation did not do their job properly, we would all be women - and journeying through MRI techniques, the nature of sexual attraction, 'neurosexism' and whether men are really better at maths. With fresh and persuasive research and with his customary intelligence and curiosity, Lewis Wolpert sets out to make his mark on this controversial topic - and makes some surprising discoveries along the way.

Why does every society around the world have a religious tradition of some sort? Professor Lewis Wolpert investigates the nature of belief and its causes. He looks at belief's psychological basis and its possible evolutionary origins in physical cause and effect. Wolpert explores the different types of belief - including that of animals, of children, of the religious, and of those suffering from psychiatric disorders. And he asks whether it is possible to live without belief at all, or whether it is a necessary component of a functioning society.

From a single cell - a fertilized egg - comes an elephant, a fly, or a human. How does this astonishing feat happen? How does the egg 'know' what to become? How does it divide into the different cells, the separate tissues, the brain, the fingernail - every tiniest detail of the growing foetus? These are the questions that the field of developmental biology seeks to answer. It is an area that is closely linked to genetics, evolution, and molecular biology. The processes are deeply rooted in evolutionary history; the information is held in genes whose vital timings in switching on and off is orchestrated by a host of proteins expressed by other genes. Timing is of the essence. Here, the distinguished developmental biologist Lewis Wolpert gives a concise account of what we now know about development, discussing the first vital steps of growth, the patterning created by Hox genes and the development of form, embryonic stem cells, the timing of gene expression and its management, chemical signalling, and growth. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Depression is a major cause of morbidity throughout the world. Given that between 8 and 12% of the population (in most countries) will suffer from depression at some point in their lives, it is clearly a significant public health problem. As our knowledge of this illness has expanded in recent years, it has become clear that depression can no longer be viewed as a simple disorder of the brain. It has to be seen as a series of behavioural and biological changes that span mind, brain, genes, and body - indeed affecting both psychological and physical health. This book brings together world leaders in research on depression, to discuss, for the first time, in an interdisciplinary setting, both classical and innovative ideas to understand this devastating disorder. It presents neurobiological, psychological, genetic and evolutionary models, with a particular emphasis on the mechanisms linking the brain to the endocrine and the immune systems, and therefore linking depression to physical health. Opening with a powerful, personal, account of depression, that conveys something of the all-consuming, debilitating, nature of this illness, the book then presents cutting edge research from those at the frontiers of work in this area. The book will be valuable for all psychiatrists, clinical psychologists and neuroscientists seeking a state-of-the-art of this global problem

Ancient Greece was the birthplace of science, which developed in the Hellenized culture of ancient Rome. This book, written by seventeen international experts, examines the role and achievement of science and mathematics in Greek antiquity through discussion of the linguistic, literary, political, religious, sociological, and technological factors which influenced scientific thought and practice. It locates science within ancient Greek society and culture, investigates its impact upon that society, and identifies it as a cultural phenomenon deserving no less attention than literary or artistic creativity.

The popular stereotype of the scientist as mad boffin or weedy nerd has been peddled widely in film and fiction, with the implication that the world of science is far removed from the intellectual and emotional messiness of other human activities. In Passionate Minds, distinguished scientist Lewis Wolpert investigates the style and motivation of some of the most eminent scientists in the world. In this stimulating collection of conversations, scientists in fields as diverse as particle physics and evolutionary biology explore how their backgrounds have shaped their careers and discoveries - how being an outsider or an "innocent" can play an invaluable role in overcoming conventional barriers to new understanding. Being a little crazy does seem to help. As Nobel laureate for physics Sheldon Glashow says, "If you would simply take all the kookiest ideas of the early 1970s and put them together you would have made for yourself the theory which is, in fact, the correct theory of nature, so it was like madness..." These personal explorations with individual scientists are not only accessible and truly fascinating in their insights into the minds of some of the greatest men and women of science, but they also provide a strong case that the life and works of our leading scientists are at least as illuminating and interesting as the personalities of the latest literary prizewinners. A sequel to A Passion for Science, this book will delight and intrigue scientists and non-scientists alike.

Everything about our existence-movement and memory, imagination and reproduction, birth, and ultimately death-is governed by our cells. They are the basis of all life in the universe, from bacteria to the most complex animals. In the tradition of the classic Lives of a Cell, but with the benefit of the latest research, Lewis Wolpert demonstrates how human life grows from a single cell into a body, an incredibly complex society of billions of cells. Wolpert goes on to examine the science behind topics that are much discussed but rarely understood stem-cell research, cloning, DNA, cancer and explains how all life on earth evolved from just one cell. Lively and passionate, this is an accessible guide to understanding the human body and life itself."

Why do 70 percent of Americans believe in angels, while others are convinced that they were abducted by aliens? What makes people believe in improbable things when all the evidence points to the contrary? And don't almost all of us, at some time or another, engage in magical thinking?In Six Impossible Things Before Breakfast, evolutionary biologist Lewis Wolpert delves into the important and timely debate over the nature of belief, looking at its psychological foundations to discover just what evolutionary purpose it could serve. Wolpert takes us through all that science can tell us about the beliefs we feel are instinctive. He deftly explores different types of belief those of children, of the religious, and of those suffering from psychiatric disorders and he asks whether it is possible to live without belief, or whether it is a necessary component of a functioning society."

An age old mystery, the development of the microscopic embryo into exceedingly complex plants and animals--into roses and cacti, elephants and blue whales, apes and human beings--stands as one of the most fundamental and important questions facing modern biologists. How does one cell give rise
to so many millions of cells? How do they divide so as to form hearts, brains, eyes, and ears? Where in this pin-head-sized object is all this information encoded? Now, in The Triumph of the Embryo, biologist Lewis Wolpert answers these and other questions in a lucid tour of embryology, which offers
the latest theories in this fascinating field.
Filled with rich and unusual examples, metaphors, and descriptions, Wolpert moves beyond his overall narrative to discuss the many issues it raises, such as aging, cancer, regeneration, and evolution. Readers discover why all calico cats are female; encounter a fruit fly engineered to grow a leg
out of its head; and find out why there seems to be a 110 year age barrier for the human body. Clearly written and illustrated with striking examples, The Triumph of the Embryo offers a dazzling look at the marvels of modern biology.