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This book summarizes the progress made to functional immobilize G
protein-coupled receptors (GPCRs) through site-specific or
orientated recognition in both non-covalent and covalent manners.
The last decade is the dawn of the "post-structural biology" era
for G protein-coupled receptor research. As an emerging approach
for state-of-the-art immobilization, this book discusses efforts to
explore the elegance of naturally-occurring biochemical reactions
by using their high specificity and robust reactivity in the
complex system, such as site-specific conjugation by covalent
recognition between enzymes and their substrates. With the
perspective of protein-drug interactions, this book also reviews
the applications of protein immobilization, with an emphasis on G
protein-coupled receptors, in drug discovery and protein-ligand
interaction analysis. In addition, the merits, opportunities and
disadvantages are analyzed for different immobilization methods,
and a perspective for future directions is presented. Given its
scope, this book appeals to a broad readership, particularly
researchers engaged in the field of analytical chemistry,
bioconjugate chemistry, and chemical biology, and other related
field, as well as teachers of relevant majors in colleges and
universities.
This book is an autobiographical interview with Chinese Academician
Yuan Wang on his experience in mathematical research. The book
looks back on Wang's collaboration with his teacher Hua Loo-Keng
and younger scholars, offering insights into fruitful cooperation
in mathematical research. In this book, Yuan Wang’s path of
studying Goldbach conjecture is revealed in detail from motivation
to method. Then his work on algebraic number theory is traced back
in a separate chapter. The book ends with two chapters which
introduce Wang’s interest in history of mathematics and his
hobbies outside of mathematical research. Wang shows how a
mathematician can in the same time be a historical and popular
science writer and, in particular, a well-received
calligrapher. The book is intended for undergraduate and
graduate students studying number theory. Researchers who are
willing to learn from the experience of an established
mathematician, as well as math amateurs and general audience who
are interested in Yuan Wang's life story might also find this book
appealing.
Therapeutic Targets For Diabetic Retinopathy: A Translational
Approach offers a consolidated view of this complex disorder by
summarizing the latest evidence-based studies and translating their
findings into practical, actionable knowledge. This concise
resource covers the fundamentals of diabetic retinopathy and
diabetic macular edema with an emphasis on basic science and
therapeutic targets on the horizon. Ophthalmologists, optometrists,
and researchers will find the translational approach to this common
eye disorder to be useful in both research and clinical practice
settings. Takes a concise yet comprehensive approach to diabetic
eye disorders, covering basic science as well as therapeutic agents
with both current and future clinical applications. Covers current
diagnostic and management guidelines as well developments on the
horizon that are likely to improve patient outcomes. Explains the
pathophysiological mechanisms of diabetic retinopathy and diabetic
macular edema from both a basic and clinical perspective, helping
readers seek promising new therapeutic targets. Consolidates
today's available information on this timely topic into a single,
convenient resource.
Spatial Cognitive Engine Technology discusses the increase in user
demand for satellite wireless communication services that has led
to the increasing development of spectrum resources and the fixed
spectrum allocation mode which makes the utilization rate of
spectrum resources lower. As an intelligent spectrum sharing
technology, cognitive radio has innovated the traditional spectrum
management system and is one of the effective ways to solve the
above-mentioned problems. As the core of satellite cognitive radio,
the spatial cognitive engine can use artificial intelligence to
dynamically configure working parameters according to changes in
the communication environment and user needs.
This book presents a new perspective on so far neglected important
areas in clinical sport psychology and sport psychiatry. The
authors use the results of an empirical qualitative and
transcultural study, to evaluate post psychological traumata of
"training peak, performance low" syndrome in sport. The results
support the view of athlete, the symptoms are severe enough to
constitute a clinical diagnosis, may suffer under depression from
two medical psychological standard systems - in this case,
traditional Chinese medicine (TCM) - offer the same results as
international standard systems - in this case, Diagnostic and
Statistical Manual of Mental Disorders, Fourth Edition, Text
Revision (DSM IV TR). The book speaks to professionals in sport
sciences, sociology, psychology and medicine. It specifically is of
relevance for coaches, athletes, sport managers, mental training
counselors and to anyone who is interested in serious sport
practice.
This book presents a new perspective on so far neglected important
areas in clinical sport psychology and sport psychiatry. The
authors use the results of an empirical qualitative and
transcultural study, to evaluate post psychological traumata of
"physical injury" in sport. An ethnically homogenous sample (n=7)
of Chinese athletes suffering from sport injury and achievement
stagnation identified by key informants was included. Symptoms of
case 2 met criteria for Major Depressive Episode in DSM IV TR, and
Heart Kidney Deficiency Depression in TCM. Case 6 suffered from
Adjustment Disorders with Anxiety and Depression, and Heart Spleen
Deficiency Depression and Pain, case 7 had a history of Adjustment
Disorders with Anxiety and Depression and Dysthymic Disorder, Heart
Spleen Deficiency Depression. The book speaks to professionals in
sport sciences, sociology, psychology and medicine. It specifically
is of relevance for coaches, athletes, sport managers, mental
training counselors and to anyone who is interested in serious
sport practice.
This book presents a new perspective on so far neglected important
areas in clinical sport psychology and sport psychiatry. The
authors use the results of an empirical qualitative and
transcultural study, to evaluate post psychological traumata after
"non functional over reaching," "over training syndrome" or "over
racing syndrome" in sport. The results support the view of athlete,
the symptoms are severe enough to constitute a clinical diagnosis,
may suffer under depression from two medical psychological standard
systems - in this case TCM - offer the same results as
international standard systems - in this case DSM IV TR, and must
not always indicate display tenacity under exhaustion could be a
symbol of strong toughness in sport. The book speaks to
professionals in sport sciences, sociology, psychology and
medicine. It specifically is of relevance for coaches, athletes,
sport managers, mental training counselors and to anyone who is
interested in serious sport practice.
This is the first transcultural mental health project focusing on
sport. The book highlights the psychological problems and mental
crisis of athletes beyond the competition from "Western" and
Eastern cultural perspectives as reflected by DSM IV TR and
Traditional Chinese Medical Psychology (TCMP). The first chapter
offers an overview of the transcultural approach in sport. The
second chapter presents a basic introduction of the diagnostical
systems of DSM IV TR and TCMP. The third chapter is focusing on
case studies of athletes from different cultural backgrounds,
especially on Asian athletes, and mainly on the previous research
on DSM depression and TCM You Y depression. It is useful to
professionals in sport sciences, psychology, medicine, sociology,
and cultural anthropology. Coaches, athletes in all sport
disciplines and sport managers will equally benefit as everyone
practicing or interested in sports.
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