This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the "post-structural biology" era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.

This book is an autobiographical interview with Chinese Academician Yuan Wang on his experience in mathematical research. The book looks back on Wang's collaboration with his teacher Hua Loo-Keng and younger scholars, offering insights into fruitful cooperation in mathematical research. In this book, Yuan Wang’s path of studying Goldbach conjecture is revealed in detail from motivation to method. Then his work on algebraic number theory is traced back in a separate chapter. The book ends with two chapters which introduce Wang’s interest in history of mathematics and his hobbies outside of mathematical research. Wang shows how a mathematician can in the same time be a historical and popular science writer and, in particular, a well-received calligrapher.  The book is intended for undergraduate and graduate students studying number theory. Researchers who are willing to learn from the experience of an established mathematician, as well as math amateurs and general audience who are interested in Yuan Wang's life story might also find this book appealing.

Therapeutic Targets For Diabetic Retinopathy: A Translational Approach offers a consolidated view of this complex disorder by summarizing the latest evidence-based studies and translating their findings into practical, actionable knowledge. This concise resource covers the fundamentals of diabetic retinopathy and diabetic macular edema with an emphasis on basic science and therapeutic targets on the horizon. Ophthalmologists, optometrists, and researchers will find the translational approach to this common eye disorder to be useful in both research and clinical practice settings. Takes a concise yet comprehensive approach to diabetic eye disorders, covering basic science as well as therapeutic agents with both current and future clinical applications. Covers current diagnostic and management guidelines as well developments on the horizon that are likely to improve patient outcomes. Explains the pathophysiological mechanisms of diabetic retinopathy and diabetic macular edema from both a basic and clinical perspective, helping readers seek promising new therapeutic targets. Consolidates today's available information on this timely topic into a single, convenient resource.

Spatial Cognitive Engine Technology discusses the increase in user demand for satellite wireless communication services that has led to the increasing development of spectrum resources and the fixed spectrum allocation mode which makes the utilization rate of spectrum resources lower. As an intelligent spectrum sharing technology, cognitive radio has innovated the traditional spectrum management system and is one of the effective ways to solve the above-mentioned problems. As the core of satellite cognitive radio, the spatial cognitive engine can use artificial intelligence to dynamically configure working parameters according to changes in the communication environment and user needs.

This book presents a new perspective on so far neglected important areas in clinical sport psychology and sport psychiatry. The authors use the results of an empirical qualitative and transcultural study, to evaluate post psychological traumata of "training peak, performance low" syndrome in sport. The results support the view of athlete, the symptoms are severe enough to constitute a clinical diagnosis, may suffer under depression from two medical psychological standard systems - in this case, traditional Chinese medicine (TCM) - offer the same results as international standard systems - in this case, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM IV TR). The book speaks to professionals in sport sciences, sociology, psychology and medicine. It specifically is of relevance for coaches, athletes, sport managers, mental training counselors and to anyone who is interested in serious sport practice.

This book presents a new perspective on so far neglected important areas in clinical sport psychology and sport psychiatry. The authors use the results of an empirical qualitative and transcultural study, to evaluate post psychological traumata of "physical injury" in sport. An ethnically homogenous sample (n=7) of Chinese athletes suffering from sport injury and achievement stagnation identified by key informants was included. Symptoms of case 2 met criteria for Major Depressive Episode in DSM IV TR, and Heart Kidney Deficiency Depression in TCM. Case 6 suffered from Adjustment Disorders with Anxiety and Depression, and Heart Spleen Deficiency Depression and Pain, case 7 had a history of Adjustment Disorders with Anxiety and Depression and Dysthymic Disorder, Heart Spleen Deficiency Depression. The book speaks to professionals in sport sciences, sociology, psychology and medicine. It specifically is of relevance for coaches, athletes, sport managers, mental training counselors and to anyone who is interested in serious sport practice.

This book presents a new perspective on so far neglected important areas in clinical sport psychology and sport psychiatry. The authors use the results of an empirical qualitative and transcultural study, to evaluate post psychological traumata after "non functional over reaching," "over training syndrome" or "over racing syndrome" in sport. The results support the view of athlete, the symptoms are severe enough to constitute a clinical diagnosis, may suffer under depression from two medical psychological standard systems - in this case TCM - offer the same results as international standard systems - in this case DSM IV TR, and must not always indicate display tenacity under exhaustion could be a symbol of strong toughness in sport. The book speaks to professionals in sport sciences, sociology, psychology and medicine. It specifically is of relevance for coaches, athletes, sport managers, mental training counselors and to anyone who is interested in serious sport practice.

This is the first transcultural mental health project focusing on sport. The book highlights the psychological problems and mental crisis of athletes beyond the competition from "Western" and Eastern cultural perspectives as reflected by DSM IV TR and Traditional Chinese Medical Psychology (TCMP). The first chapter offers an overview of the transcultural approach in sport. The second chapter presents a basic introduction of the diagnostical systems of DSM IV TR and TCMP. The third chapter is focusing on case studies of athletes from different cultural backgrounds, especially on Asian athletes, and mainly on the previous research on DSM depression and TCM You Y depression. It is useful to professionals in sport sciences, psychology, medicine, sociology, and cultural anthropology. Coaches, athletes in all sport disciplines and sport managers will equally benefit as everyone practicing or interested in sports.