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A review of the scientific evidence on the effects of cannabinoids
on brain and behavioral functioning, with an emphasis on potential
therapeutic use. The cannabis plant has been used for recreational
and medicinal purposes for more than 4,000 years, but the
scientific investigation into its effects has only recently yielded
useful results. In this book, Linda Parker offers a review of the
scientific evidence on the effects of cannabinoids on brain and
behavioral functioning, with an emphasis on potential therapeutic
uses. Parker describes the discovery of tetrahydocannbinol (THC),
the main psychoactive component of cannabis, and the further
discovery of cannabinoid receptors in the brain. She explains that
the brain produces chemicals similar to THC, which act on the same
receptors as THC, and shows that the endocannabinoid system is
involved in all aspects of brain functioning. Parker reports that
cannabis contains not only the psychoactive compound THC, but also
other compounds of potential therapeutic benefit, and that one of
them, cannabidiol (CBD), shows promise for the treatment of pain,
anxiety, and epilepsy. Parker reviews the evidence on cannabinoids
and anxiety, depression, mood, sleep, schizophrenia, learning and
memory, addiction, sex, appetite and obesity, chemotherapy-induced
nausea, epilepsy, and such neurodegenerative disorders as multiple
sclerosis and Alzheimer's Disease. Each chapter also links the
scientific evidence to historical and anecdotal reports of the
medicinal use of cannabis. As debate about the medical use of
marijuana continues, Parker's balanced and objective review of the
fundamental science and potential therapeutic effects of cannabis
is especially timely.
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