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Nanotechnology Tools for Infections Control: Scanning New Horizons
on Next-Generation Therapies to Eradicate Pathogens and Fight Drug
Resistance provides an overview of recent strategies to build
nanotechnology platforms, with a specific focus on biocompatible
and biodegradable nanosystems. Particular attention is given to
responsive nanoparticles, which are able to sense and respond to
specific external stimuli (e.g., temperature, pH). The book
includes details of the rationale behind the design of the raw
materials, synthetic procedures and characterization techniques. It
also introduces a new generation of nanomaterials, commonly named
as ‘nanobots’, which are able to self-propel in response to
external stimuli. Subsequent sections of the book focus on the
applications of nanosystems as an alternative approach to standard
antibiotics. The chapters describe their pharmokinetic and dynamics
within the body, their ability to cross biological barriers and how
they distribute within different body compartments. In this
respect, a dedicated section highlights the crucial role of the
immune system, as well as of protein corona, in changing the
nanoparticles retention within the body. Coverage is also given to
describe how nanosystems access different cells and their
intracellular trafficking.
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