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Horizontal gene transfer (HGT) events encompass processes as varied
as the exchange of genetic material between microbes coexisting in
the same environment, between symbiotic bacteria and their
eukaryotic hosts, and the evolution of organelles by symbiosis, in
which whole genomes are acquired. In Horizontal Gene Transfer:
Genomes in Flux, expert researchers contribute an overview of HGT
concepts as well as specific case histories that highlight the most
current progress to inspire future work. Divided into three
sections, the volume begins with an overview of terminology,
concepts and the implications of HGT on current evolutionary
thought and philosophy, and continues with methods involving
computer and bioinformatics analyses of genomic data as well as
molecular biology techniques for identifying, quantifying, and
differentiating instances of HGT. A section of case studies
follows, which provides detailed accounts of how HGT has shaped
evolution across the diversity of organisms and organismal
lineages. As a volume of the highly successful Methods in Molecular
Biology (TM) series, this work provides the kind of detailed
description and implementation advice that is crucial for getting
optimal results. Cutting-edge and thoroughly detailed, Horizontal
Gene Transfer: Genomes in Flux examines how HGT has contributed to
genome evolution and how understanding HGT impacts our ability to
accurately reconstruct and comprehend the web-like evolutionary
history in order to aid scientists in furthering their own
research.
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