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The notion that fatty acid intake may influence the incidence of
tumorigeneis and cancer has been studied intensively in vivo and in
vitro for more than thirty years and seems to be widely accepted.
Ranging form epidemiological studies to those conducted using cell
cuture models, most studies provide evidence that certain long
chain polyunsaturated fatty acids are able to inhibit the
development of cancer or slow down tumor growth. However, the
cellular and molecular mechanisms responsible for these effects
have not yet been clarified, although various hypotheses exist.
Therefore the aim of this chapter is to discuss: PART I: The
epidemiological evidence; PART II: The modulation of signaling
pathways and the regulation of cell death by fatty acids; and PART
III: To give an overview on clinically relevant fatty acids and
rationale for adjuvant fatty acid therapy.
Contemporary Irish Plays showcases the new drama that has emerged
since 2008. Featuring a blend of established and emerging writers,
the anthology shows how Irish writers are embracing new methods of
theatre-making to explore exciting new themes - while also finding
new ways to come to terms with the legacies of the Troubles and the
Celtic Tiger. The Last Days of a Reluctant Tyrant tells the tragic
story of a family disintegrating, having lost its moral values.
Written by leading Irish playwright Tom Murphy, it was produced at
the Abbey Theatre in June 2009. Drum Belly is a fascinating play
about the Irish mafia in late 1960s' New York. It premiered at the
Abbey Theatre in 2012. Previously unpublished, Planet Belfast by
Rosemary Jenkinson is about a woman named Alice - Stormont's only
Green MLA who must toe a delicate line between large, sectarian
power bases in order to promote an environmental agenda in Northern
Ireland. Forgotten features the interconnecting stories of four
elderly people living in retirement homes and care facilities
around Ireland, who range in age from 80 to 100 years old.Desolate
Heaven is a story about two young girls hoping to find freedom from
home in the trappings of love. It was first performed at Theatre
503, London, in 2013 Written for the 2012 Dublin Theatre Festival,
and previously unpublished, The Boys of Foley Street by Louise Lowe
is a piece of site-specific theatre which led audience members on a
tour of the backstreets of inner-city Dublin. Freefall is a sharp,
humorous and exhilarating look at the fragility of a human life,
blending impressionistic beauty, poignancy and comedy. Edited by
the leading scholar on Irish theatre, Patrick Lonergan,
Contemporary Irish Plays is a timely reminder of the long-held
tradition and strength of Irish theatre which blossoms even in its
new-found circumstances.
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R270
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Discovery Miles 1 190
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