Applied Pathophysiology for the Advanced Practice Nurse, Second Edition is a comprehensive resource that serves as a bridge between clinical experience and the advanced knowledge necessary for the role of an APRN. It helps graduate students navigate the data and presentation of symptoms that must be considered when making a diagnosis and recommendation for treatment. This unique text includes expanded pathophysiology content across the life span and information to meet the needs of many advanced practice population areas, including pediatrics, psychiatric mental health, and gerontology. It also incorporates information from both an acute and primary care focus. The Second Edition was thoroughly updated to offer the latest information and data, including a new section on microbiology and infectious diseases with information on COVID-19, a new section on the endocannabinoid system, new information on genetic testing principles, several newly added psychiatric mental health disorders, and more timely topics. The practical approach to discussing the complex topic of pathophysiology sets Applied Pathophysiology for the Advanced Practice Nurse, Second Edition apart from other texts. With this resource, students will be better prepared to make sound clinical decisions in their APRN role no matter the setting.