The increasingly widespread production of toxins by marine and freshwater microalgae raises serious concerns regarding seafood and drinking water safety. This book compiles studies on the influence of climate change on the spreading of toxin-producing species in aquatic systems. The chemistry and biology of toxin production is revised and an outlook on control and prevention of the toxins' impact on human and animal health is given.

Climate Change and Mycotoxins highlights the importance of the continuous study of climate change impacts on mycotoxigenic fungi and their toxins in food and feed crops. Changing climate conditions across every geographical zone greatly affect rainfall, temperature and concentration of greenhouse gases leading to loss in yield and quality of food crops. In outstanding contributions, the authors compile current evidence on the influence of climate change on mycotoxigenic fungi and mycotoxins in food crops pre- and postharvest and during storage of food and animal feed. The chemistry and biology of toxin production is revised and an outlook on control and prevention of the toxin's impact on food and animal feed is given. The editors recommend this book to mycologists, mycotoxicologists, pathologists, epidemiologists, toxicologists, physicians, veterinarians, nutritionists, the food and feed industries, legislators, analytical chemists, microbiologists, or students of these fields. * Unique compilation on the impact of climate change on mycotoxins based on observed trends over the last 10 years. * Special focus on the implications for food and feed safety. * Latest advances on prediction and prevention of mycotoxin threats to human and animal health. About the Editors Luis M. Botana Is a full Professor of Pharmacology at the University of Santiago, from 2004-2012 director of the Department of Pharmacology and former Fogarty Fellow at the School of Medicine of the Johns Hopkins University. He has been director of the European Reference Laboratory for Marine Toxins from 2004 to 2009. He is author of 25 international patents, over 300 scientific papers and editor of 10 international books. Maria J. Sainz Is an associate Professor of Agriculture and Forage Production and Conservation at the University of Santiago de Compostela. She has been a visiting scientist at the Rothamsted Experimental Station and for ten years head of the department of Plant Production. Her research interests focus on fungal pathogen detection and diagnostics, mycorrhizal fungi in crop protection and production, and mycotoxigenic fungi and mycotoxins on forage crops and animal feed.

In Climate Change and Marine and Freshwater Toxins the editors have assembled contributions from a team of international experts to expand the framework for an appropriate assessment of climate change impacts on aquatic toxins. While the production of toxins by microalgae has been known for decades, establishing a factual link supported by scientific evidence is a very complex endeavor. The increasing frequency and distribution of toxic blooms for example continue to raise serious concerns regarding seafood and drinking water safety. This book compiles current evidence on the influence of climate change on the spreading of toxin producing species in aquatic systems. The chemistry and biology of toxin production is revised and an outlook on control and prevention of the toxin's impact on human and animal health is given. * Compelling quantitative evidence of complex interactions from primary toxin producers and along the food chain. * Latest advances on prediction and prevention of water toxin threats to human and animal health. * A must read for insights into aquatic toxins and their modification by climatic conditions. About the Editors Luis M. Botana Is a full Professor of Pharmacology at the University of Santiago, from 2004-2012 director of the Department of Pharmacology and former Fogarty Fellow at the School of Medicine of the Johns Hopkins University. He has been director of the European Reference Laboratory for Marine Toxins from 2004 to 2009. He is author of 25 international patents, over 300 scientific papers and editor of 10 international books. M. Carmen Louzao Is a Professor of Pharmacology at the University of Santiago de Compostela since 1997. She was a postdoctoral fellow in the National Institute of Environmental Health Sciences (NIEHS) from 1994 to 1995. She is author of over 70 scientific publications in the field of Toxicology, Biochemistry, and Immunology and 20 reviews and book chapters. Natalia Vilarino Currently teaches Pharmacology to Veterinary Medicine students and participates actively in the research activities of the Department of Pharmacology, University of Santiago de Compostela, since 2005. She was a postdoctoral fellow at the Johns Hopkins Asthma and Allergy Center for 4 years. She is author of over 50 scientific papers in the fields of Toxicology, Analytical Chemistry and Immunology.

The last few years have brought about many changes in the field of marine and freshwater toxins, with advances in analytical technology and the realization that these toxins are a global issue. Offering a complete reference guide, Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Third Edition addresses all aspects of the social and scientific influence of phytotoxins, from legislation and monitoring to new drug development. Covering many new topics, the book examines three main aspects: monitoring of toxins; chemical, mechanistic, and toxicological diversity; and detection technologies. New to this edition: 35 new chapters and 5 updated chapters A focus on state-of-the-art methodology Coverage of new technologies to cultivate algae and to identify, isolate, and quantify toxins Regulatory changes Climate change evidence Expanded information on toxicology Part I of the book includes an overview and reviews general issues related to toxin detection, ecology, and diversity, and effects of climate change. Part II covers impacts of toxins regarding epidemiology, toxicology, economics, and surveillance. Part III explores available detection technologies, such as functional assays, biosensors, mass spectrometry, nanotechnology, and more. In addition, standard reference materials for toxins are discussed. Parts IV to VI provide detailed descriptions of toxin chemical diversity, biological sources, and modes of action. Part VII addresses the use of toxins as starting points for therapeutic drugs for cancer, neurological disorders, and for novel antibiotics.

The last few years have brought about many changes in the field of marine and freshwater toxins, with advances in analytical technology and the realization that these toxins are a global issue. Offering a complete reference guide, Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection, Third Edition addresses all aspects of the social and scientific influence of phytotoxins, from legislation and monitoring to new drug development. Covering many new topics, the book examines three main aspects: monitoring of toxins; chemical, mechanistic, and toxicological diversity; and detection technologies. New to this edition: 35 new chapters and 5 updated chapters A focus on state-of-the-art methodology Coverage of new technologies to cultivate algae and to identify, isolate, and quantify toxins Regulatory changes Climate change evidence Expanded information on toxicology Part I of the book includes an overview and reviews general issues related to toxin detection, ecology, and diversity, and effects of climate change. Part II covers impacts of toxins regarding epidemiology, toxicology, economics, and surveillance. Part III explores available detection technologies, such as functional assays, biosensors, mass spectrometry, nanotechnology, and more. In addition, standard reference materials for toxins are discussed. Parts IV to VI provide detailed descriptions of toxin chemical diversity, biological sources, and modes of action. Part VII addresses the use of toxins as starting points for therapeutic drugs for cancer, neurological disorders, and for novel antibiotics.