Designed to provide a highly visual reference for surgeons and other members of the patient management team, Atlas of Intestinal Stomas is based on the 1967 gold standard text, Turnbull and Weakly's Atlas of Intestinal Stomas. Additions include chapters on anatomy and physiology, biliary stomas, pediatric ostomies, the continent ileostomy, urostomy, laparoscopic stoma construction, stomas in trauma surgery, stomas for antegrade continence enema, percutaneous ostomies, and quality of life. There are also sections on ileostomy, colostomy, enterostomal therapy and on the management of complications of stomas such as management of the high output ostomy, enterocutaneous fistula, parastomal hernia, prolapse, and skin conditions. The Cleveland Clinic pioneered the entire practice of ostomies, beginning in 1858 and continuing to this day as the world's leading academic and clinical center. The editors and contributors are all current or former Cleveland Clinic physicians and instructors. The fundamental focus of the book is not only how to install ostomies, but how to avoid complications and how to treat complications when they arise. Atlas of Intestinal Stomas will be of great value to colorectal and general surgeons, both in practice and in training.

This seventh volume, divided into four parts, addresses the biological determinates of reinforcement and memory. Covers topics in electrical brain stimulation, drugs and reinforcement, and cellular mechanisms.

This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.

Luck permeates our lives, and this raises a number of pressing questions: What is luck? When we attribute luck to people, circumstances, or events, what are we attributing? Do we have any obligations to mitigate the harms done to people who are less fortunate? And to what extent is deserving praise or blame affected by good or bad luck? Although acquiring a true belief by an uneducated guess involves a kind of luck that precludes knowledge, does all luck undermine knowledge? The academic literature has seen growing, interdisciplinary interest in luck, and this volume brings together and explains the most important areas of this research. It consists of 39 newly commissioned chapters, written by an internationally acclaimed team of philosophers and psychologists, for a readership of students and researchers. Its coverage is divided into six sections: I: The History of Luck II: The Nature of Luck III: Moral Luck IV: Epistemic Luck V: The Psychology of Luck VI: Future Research. The chapters cover a wide range of topics, from the problem of moral luck, to anti-luck epistemology, to the relationship between luck attributions and cognitive biases, to meta-questions regarding the nature of luck itself, to a range of other theoretical and empirical questions. By bringing this research together, the Handbook serves as both a touchstone for understanding the relevant issues and a first port of call for future research on luck.

Molecular Genetics of Colorectal Neoplasia A Primer for the Clinician provides the latest information on the genetics of colorectal cancer within a context of basic genetics, describing the subject in understandable language and making it clinically relevant. In this way, clinicians can become familiar with genetic terms and techniques related to colorectal neoplasia, providing a background upon which to build an appreciation of future advances and an ability to include them in the practicalities of patient care.

This edition is intended for the healthcare provider or industry concerned with colorectal neoplasia: including general and colorectal surgeons, pathologists, oncologists, gastroenterologists, internal medicine and family practice physicians, nurses, geneticists, counsellors, registry co-ordinators, epidemiologists, and statisticians.

This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.

Luck permeates our lives, and this raises a number of pressing questions: What is luck? When we attribute luck to people, circumstances, or events, what are we attributing? Do we have any obligations to mitigate the harms done to people who are less fortunate? And to what extent is deserving praise or blame affected by good or bad luck? Although acquiring a true belief by an uneducated guess involves a kind of luck that precludes knowledge, does all luck undermine knowledge? The academic literature has seen growing, interdisciplinary interest in luck, and this volume brings together and explains the most important areas of this research. It consists of 39 newly commissioned chapters, written by an internationally acclaimed team of philosophers and psychologists, for a readership of students and researchers. Its coverage is divided into six sections: I: The History of Luck II: The Nature of Luck III: Moral Luck IV: Epistemic Luck V: The Psychology of Luck VI: Future Research. The chapters cover a wide range of topics, from the problem of moral luck, to anti-luck epistemology, to the relationship between luck attributions and cognitive biases, to meta-questions regarding the nature of luck itself, to a range of other theoretical and empirical questions. By bringing this research together, the Handbook serves as both a touchstone for understanding the relevant issues and a first port of call for future research on luck.

For more than 25 years, Current Therapy in Colon and Rectal Surgery has been the go-to resource for preparing for the American Board of Surgery certification exam. Following in this tradition, the 3rd Edition offers a comprehensive, contemporary summary of treatment options for colorectal diseases, with a focus on practical clinical science and applications. In a single, portable volume, you'll find complete coverage of new diagnostic modalities, medical therapeutics, and surgical treatment options, including minimally invasive surgery. Easy to read and digest, it provides a quick consultation with experts on the essentials of colon and rectal surgery. Consult this title for a quick overview before you enter the OR, and use it as a review tool for board certification and recertification. Nearly 100 succinct chapters, just 3 or 4 pages each, written by leading experts in colorectal surgery. Five chapters devoted exclusively to different aspects of rectal cancer. Other key topics include minimally invasive surgery, reparative surgery, maturing outcomes, and managing surgical risk. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. New chapters focus on hot topics such as intestinal transplants, enhanced recovery programs, and the management of peristomal hernias. Updated information on the molecular biology of colorectal cancer and its implications for therapy. With 137 additional contributing experts

Recent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the development of new diagnostic tools. This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential relevance to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineering have, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting.

Designed to provide a highly visual reference for surgeons and other members of the patient management team, Atlas of Intestinal Stomas is based on the 1967 gold standard text, Turnbull and Weakly's Atlas of Intestinal Stomas. Additions include chapters on anatomy and physiology, biliary stomas, pediatric ostomies, the continent ileostomy, urostomy, laparoscopic stoma construction, stomas in trauma surgery, stomas for antegrade continence enema, percutaneous ostomies, and quality of life. There are also sections on ileostomy, colostomy, enterostomal therapy and on the management of complications of stomas such as management of the high output ostomy, enterocutaneous fistula, parastomal hernia, prolapse, and skin conditions. The Cleveland Clinic pioneered the entire practice of ostomies, beginning in 1858 and continuing to this day as the world's leading academic and clinical center. The editors and contributors are all current or former Cleveland Clinic physicians and instructors. The fundamental focus of the book is not only how to install ostomies, but how to avoid complications and how to treat complications when they arise. Atlas of Intestinal Stomas will be of great value to colorectal and general surgeons, both in practice and in training.

Molecular Genetics of Colorectal Neoplasia A Primer for the Clinician provides the latest information on the genetics of colorectal cancer within a context of basic genetics, describing the subject in understandable language and making it clinically relevant. In this way, clinicians can become familiar with genetic terms and techniques related to colorectal neoplasia, providing a background upon which to build an appreciation of future advances and an ability to include them in the practicalities of patient care. This edition is intended for the healthcare provider or industry concerned with colorectal neoplasia: including general and colorectal surgeons, pathologists, oncologists, gastroenterologists, internal medicine and family practice physicians, nurses, geneticists, counsellors, registry co-ordinators, epidemiologists, and statisticians.

This encyclopedia, which constitutes a wide ranging and authoritative collection of academic articles, covers the sedimentological aspects of sediments and sedimentary rocks. As such the encyclopedia provides a comprehensive, one-volume reference work for students and faculty in universities, and for professionals in geology and allied disciplines (geography, engineering, environmental studies), as well as informed lay readers.

2017 Alf Andrew Heggoy Book Prize Winner Over a span of thirty years in the late nineteenth and early twentieth centuries, the French Caribbean islands of Martinique and Guadeloupe endured natural catastrophes from all the elements-earth, wind, fire, and water-as well as a collapsing sugar industry, civil unrest, and political intrigue. These disasters thrust a long history of societal and economic inequities into the public sphere as officials and citizens weighed the importance of social welfare, exploitative economic practices, citizenship rights, racism, and governmental responsibility. Paradise Destroyed explores the impact of natural and man-made disasters in the turn-of-the-century French Caribbean, examining the social, economic, and political implications of shared citizenship in times of civil unrest. French nationalists projected a fantasy of assimilation onto the Caribbean, where the predominately nonwhite population received full French citizenship and governmental representation. When disaster struck in the faraway French West Indies-whether the whirlwinds of a hurricane or a vast workers' strike-France faced a tempest at home as politicians, journalists, and economists, along with the general population, debated the role of the French state not only in the Antilles but in their own lives as well. Environmental disasters brought to the fore existing racial and social tensions and severely tested France's ideological convictions of assimilation and citizenship. Christopher M. Church shows how France's "old colonies" subscribed to a definition of tropical French-ness amid the sociopolitical and cultural struggles of a fin de siecle France riddled with social unrest and political divisions.

2017 Alf Andrew Heggoy Book Prize Winner Over a span of thirty years in the late nineteenth and early twentieth centuries, the French Caribbean islands of Martinique and Guadeloupe endured natural catastrophes from all the elements-earth, wind, fire, and water-as well as a collapsing sugar industry, civil unrest, and political intrigue. These disasters thrust a long history of societal and economic inequities into the public sphere as officials and citizens weighed the importance of social welfare, exploitative economic practices, citizenship rights, racism, and governmental responsibility. Paradise Destroyed explores the impact of natural and man-made disasters in the turn-of-the-century French Caribbean, examining the social, economic, and political implications of shared citizenship in times of civil unrest. French nationalists projected a fantasy of assimilation onto the Caribbean, where the predominately nonwhite population received full French citizenship and governmental representation. When disaster struck in the faraway French West Indies-whether the whirlwinds of a hurricane or a vast workers' strike-France faced a tempest at home as politicians, journalists, and economists, along with the general population, debated the role of the French state not only in the Antilles but in their own lives as well. Environmental disasters brought to the fore existing racial and social tensions and severely tested France's ideological convictions of assimilation and citizenship. Christopher M. Church shows how France's "old colonies" subscribed to a definition of tropical French-ness amid the sociopolitical and cultural struggles of a fin de siecle France riddled with social unrest and political divisions.