Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

One of the most pressing tasks in biotechnology today is to unlock the function of each of the thousands of new genes identified every day. Scientists do this by analyzing and interpreting proteins, which are considered the task force of a gene. This single source reference covers all aspects of proteins, explaining fundamentals, synthesizing the latest literature, and demonstrating the most important bioinformatics tools available today for protein analysis, interpretation and prediction. Students and researchers of biotechnology, bioinformatics, proteomics, protein engineering, biophysics, computational biology, molecular modeling, and drug design will find this a ready reference for staying current and productive in this fast evolving interdisciplinary field.

Explains all aspects of proteins including sequence and structure analysis, prediction of protein structures, protein folding, protein stability, and protein interactions

Teaches readers how to analyze their own datasets using available online databases, software tools, and web servers, which are listed and updated on the book s web companion page.

Presents a cohesive and accessible overview of the field, using illustrations to explain key concepts and detailed exercises for students."

Drawing on such process thinkers as Whitehead, Deleuze and Stengers, Innovation and Biomedicine develops a powerful framework for the analysis of Biomedical Innovation. With its sustained focus on the Pre-Exposure Prophylactic pill (PrEP) for the prevention of HIV infection, the volume explores the ethical, medical and political elements entailed in the pill's testing through offshore randomized control trials (RCTs). To this end, the key concept of 'eventuation' is elaborated and deployed in the scrutiny of the 'gold standard' status of RCTs, the role of ethics in RCTs, and the enactment of the PrEP pill as a singular entity. Further, the authors engage with affective, topological and virtual dimensions to show how PrEP's eventuation also allows for new scientific and ethical questions to be crafted. Innovation and Biomedicine is a major contribution to science and technology studies, medical sociology, and the multi-disciplinary study of HIV.

Very Large Scale Integration (VLSI) has become a necessity rather than a specialization for electrical and computer engineers. This unique text provides Engineering and Computer Science students with a comprehensive study of the subject, covering VLSI from basic design techniques to working principles of physical design automation tools to leading edge application-specific array processors.

Beginning with CMOS design, the author describes VLSI design from the viewpoint of a digital circuit engineer. He develops physical pictures for CMOS circuits and demonstrates the top-down design methodology using two design projects - a microprocessor and a field programmable gate array. The author then discusses VLSI testing and dedicates an entire chapter to the working principles, strengths, and weaknesses of ubiquitous physical design tools. Finally, he unveils the frontiers of VLSI. He emphasizes its use as a tool to develop innovative algorithms and architecture to solve previously intractable problems.

VLSI Design answers not only the question of "what is VLSI," but also shows how to use VLSI. It provides graduate and upper level undergraduate students with a complete and congregated view of VLSI engineering.

Over the years enormous effort was invested in proving ergodicity, but for a number of reasons, con?dence in the fruitfulness of this approach has waned. - Y. Ben-Menahem and I. Pitowsky [1] Abstract The basic motivation behind the present text is threefold: To give a new explanation for the emergence of thermodynamics, to investigate the interplay between quantum mechanics and thermodynamics, and to explore possible ext- sions of the common validity range of thermodynamics. Originally, thermodynamics has been a purely phenomenological science. Early s- entists (Galileo, Santorio, Celsius, Fahrenheit) tried to give de?nitions for quantities which were intuitively obvious to the observer, like pressure or temperature, and studied their interconnections. The idea that these phenomena might be linked to other ?elds of physics, like classical mechanics, e.g., was not common in those days. Such a connection was basically introduced when Joule calculated the heat equ- alent in 1840 showing that heat was a form of energy, just like kinetic or potential energy in the theory of mechanics. At the end of the 19th century, when the atomic theory became popular, researchers began to think of a gas as a huge amount of bouncing balls inside a box.

Thermal Spreading and Contact Resistance is the first book to provide a single source of information for engineers who need understand thermal spreading and contact resistance for a wide range of applications. Written by two of the leading experts in the field, it covers applications of problems where heat transfer from discrete heat sources is prevalent, including contact conductance, mass transfer, transport from super-hydrophobic surfaces, droplet/surface phase change problems, tribology, and heat transfer in micro-devices and thermal spreaders. After opening with an introduction to fundamental principles, the book goes on to cover thermal spreading in isotropic half-space regions, circular flux tubes and disc spreaders, rectangular flux channels and spreaders, orthotropic systems, and multi-source applications. Further chapters explore topics such as systems with non-uniform sink plane conductance, transient spreading resistance, and contact resistance between both non-conforming and conforming surfaces. Numerous predictive models and examples and included throughout and a useful appendix provides special functions and series solutions that readers can use to further their own research.

This innovative and thought-provoking study puts forth a compelling analysis of the constitutive nexus at the heart of the European refugee conundrum. It maps and historically contextualises some of the distinctive challenges that pervasive ethnic and cultural pluralism present to real politics as on the level of political theorizing. By systematically integrating hitherto insufficiently linked research perspectives in a novel way, it lays open a number of paradoxical constellations and regressive tendencies in contemporary European democracy. It thereby redirects attention to the ways in which liberal thought and liberal democratic institutions shape, interact with, and may even provide justification for illiberal and exclusionary practices. This book thus makes an important contribution to the analysis of post-migrant realities in Europe and the ways in which they are defined by imperial legacies, punitive migration regimes, the culturalization of mainstream politics, and the discursive construction of a European Other.

This book traces the origins and activities of the longest-standing collaborative teacher group in education, the Portfolio Group. Each chapter documents, historically and conceptually, the main intellectual moments in the evolution of the idea of knowledge communities. Authors illuminate the expansive work, research, and the leading/learning influence that the Portfolio Group has had in the local education community as well as on the international education landscape. In doing so, they illustrate the journey of a school-based, cross-institutional knowledge community and provide the proverbial light at the end of the tunnel for so many novice and newly formed groups seeking sustainability. The book demonstrates through the shared experiences of five teachers/teacher educators the ways in which varied collaborations aimed at professional development lead to teacher growth in practice, leadership, and career.

While there are no shortages of books about the Cyprus Conflict, this book offers the best summary of the negotiations around. The book comes at a critical time for the partitioned island-state of Cyprus and for those associated with the conflict and attempts to resolve it. By placing the conflict in its historical, ideological, ethno-political and geostrategic context, the book extends beyond conventional realist approaches and lays bare those less visible dimensions that are often ignored by analysts and policy-makers alike. The book is of direct interest not only to experts and students but to all those engaged in the practice of conflict resolution.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Practical guidance on how to empower people to do their best.

Filled with stories by and fascinating interviews with human capital innovators, Making a Difference Through People provides practical guidance on how to empower people to deliver their best performance by employing their guiding principles. Offering relevant strategies and tactics, each interview is preceded by an introduction that provides a biographical recap and a brief discussion of each innovator.

Mercer is the global leader for trusted HR and related financial advice, products and services. They work with clients at enhancing the financial and retirement security, health, productivity and employment relationships of the global workforce. M. Michele Burns is Chairman and Chief Executive Officer of Mercer Prior to being named Chairman and CEO of Mercer, Ms. Burns held the position of Chief Financial Officer for MMC.