|
Showing 1 - 1 of
1 matches in All Departments
The structure of eunicillin (89), a carbobicyclic diterpenoid
isolated from the Mediterranean gorgonian Eunicella stricta, was
reported in 1968 (1). At that time chlorine-containing diterpenoids
had been dis covered in the gorgonian Briareum asbestinum (2, 3),
but it was not until 1977 that the structure of the first briaran,
briarein A (211), was resolved by X-ray analysis (4). The first
trinervitane diterpenoid (26), which was isolated from
Trinervitermes termites, was reported in 1976 (5). OAc OAc ACO'....
OH 0 89 211 26 The discovery of these compounds marked the
appearance of a large and growing group of diterpenoids which are
commonly viewed as being formed from cembrane precursors by
secondary carbon-carbon bond closures. It should be emphasized,
however, that in the absence of biosynthetic evidence the question
of which groups of diterpenoids that should be classified as
cyclized cembranoids remains ambiguous. In the present article we
have included five tobacco diterpenoids (1-5) which. possess
prerequisite structural features and co occur with appropriate
cembrane precursors in tobacco. Although structurally reminiscent
of cyclized cembranoids, verticillanes, taxanes and cleomeolide are
not dealt with, since these diterpenoids of plant origin are not
believed to arise via preformed cembranoids (6-11)."
|
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.