This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

Before conclusions about Spanish in the United States can be drawn, individual communities must be studied in their own contexts. That is the goal of "Puerto Rican Discourse." One tendency of previous work on Spanish in the United States has been an eagerness to generalize the findings of isolated studies to all Latino communities, but the specific sociocultural contexts in which people -- and languages -- live often demand very different conclusions. The results of Torres' work indicate that the Spanish of Puerto Ricans living in Brentwood continues to survive in a restricted context. Across the population of Brentwood -- for Puerto Ricans of all ages and language proficiencies -- the Spanish language continues to assume an important practical, symbolic, and affective role.
An examination of the structural features of 60 oral narratives -- narrative components and the verbal tenses associated with each, overall Spanish verb use, and clause complexity -- reveals little evidence of the simplification and loss across generations found in other studies of Spanish in the United States. English-dominant Puerto Ricans are able Spanish language narrators demonstrating a wide variety of storytelling skills. The structure of their oral narratives is as complete and rich as the narratives of Spanish-dominant speakers.
The content of these oral narratives of personal experience is also explored. Too often in studies on U.S. Spanish, sociolinguists ignore the words of the community; the focus is usually on the grammatical aspects of language use and rarely on the message conveyed. In this study, oral narratives are analyzed as constructions of gendered and ethnically marked identities. The stories demonstrate the contradictory positions in which many Puerto Ricans find themselves in the United States. All of the speakers in this study have internalized, to a greater or lesser extent, dominant ideologies of gender, ethnicity, and language, at the same time that they struggle against such discourse. The analysis of the discourse of the community reveals how the status quo is both reproduced and resisted in the members' narratives, and how ideological forces work with other factors, such as attitudes, to influence the choices speakers make concerning language use. A special feature of this book is that transcripts are provided in both Spanish and English.
This volume combines ethnographic, quantitative, and qualitative discourse methodologies to provide a comprehensive and novel analysis of language use and attitudes of the Brentwood Puerto Rican community. Its rich linguistic and ethnographic data will be of interest to researchers and teachers in cultural communication, ethnic (Hispanic-American) studies, sociolinguistics, and TESL.

Why do firms die? This volume seeks to explore international and cross-disciplinary perspectives, if you like a forensic examination, autopsy or post mortem of 'how and why' companies die. This alternate perspectives flips the focus on survival, as all existing firms are in truth survivors, to consider through the metaphors of death, (with forensic analysis, autopsy, post mortems and crime scene investigations) the lessons 'dead firms' might offer. This book will contribute to the understanding of the development, antecedents, processes and consequences of corporate insolvency around the world. In general lines, insolvency is a state in which the debtor is proven unable to pay corporate debtors. We aim to explore the contemporary causes and effects of corporate cross-border insolvency (CCBI). In the realms of international business, CCBI could be mediated by events experienced during the internationalization of the firm, which may encompass a loss of capital, loss of revenue and loss of credit.

A multidisciplinary study of pre-Columbian South Americacentering on the psychoactive plant genus Anadenanthera As cultures formed and evolved in pre-Columbian South America, Anadenanthera became one of the most widely used shamanic inebriants. Anadenanthera: Visionary Plant of Ancient South America is more than a comprehensive reference on shamanic visionary substances; it is a useful tool for archeologists and pre-Columbian art historians. This thorough book examines the ritual and cultural use of Anadenanthera from prehistory to the present, along with its botany, chemistry, pharmacology, anthropology, and archeology. The earliest evidence for the use of psychoactive plants in South America is provided by remains of seeds and pods recovered from archeological sites four millennia old. Various preparations were derived from it with the intent of being a shamanic inebriant. Inhaled through the nose, smoked in pipes or as cigars, and prepared in fermented drinks, Anadenanthera served a central role in the cultural development of indigenous societies in South America. Anadenanthera: Visionary Plant of Ancient South America explores the full spectrum of information gleaned from research, covering numerous archeological sites in the Andean region, as well as discussing Amazonian shamanic rituals and lore. Analyses of the artistic expressions within the decorations of associated ceremonial paraphernalia such as ritual snuffing tubes and snuff trays are included. The text is richly illustrated with photographs and images of decorated ritual implements, and provides a comprehensive bibliography. Anadenanthera: Visionary Plant of Ancient South America explores: botanical aspects, taxonomy, and geographical distribution of Anadenanthera ethnographical, historical, and traditional aspects of Anadenanthera use chemical and pharmacological investigations of the genus and the various visionary preparations derived from itwith emphasis on the biologically active constituents theories of the mechanisms of action of the active tryptamines and carboline alkaloids comparisons of wood anatomy, morphology, and percentage of alkaloid content evaluation of stylistic and iconographic traits Anadenanthera: Visionary Plant of Ancient South America is a thorough, useful resource for archeologists, anthropologists, chemists, researchers, pre-Columbian art historians, and any layperson interested in pre-Columbian art, archeology, or visionary plants.

A multidisciplinary study of pre-Columbian South Americacentering on the psychoactive plant genus Anadenanthera As cultures formed and evolved in pre-Columbian South America, Anadenanthera became one of the most widely used shamanic inebriants. Anadenanthera: Visionary Plant of Ancient South America is more than a comprehensive reference on shamanic visionary substances; it is a useful tool for archeologists and pre-Columbian art historians. This thorough book examines the ritual and cultural use of Anadenanthera from prehistory to the present, along with its botany, chemistry, pharmacology, anthropology, and archeology. The earliest evidence for the use of psychoactive plants in South America is provided by remains of seeds and pods recovered from archeological sites four millennia old. Various preparations were derived from it with the intent of being a shamanic inebriant. Inhaled through the nose, smoked in pipes or as cigars, and prepared in fermented drinks, Anadenanthera served a central role in the cultural development of indigenous societies in South America. Anadenanthera: Visionary Plant of Ancient South America explores the full spectrum of information gleaned from research, covering numerous archeological sites in the Andean region, as well as discussing Amazonian shamanic rituals and lore. Analyses of the artistic expressions within the decorations of associated ceremonial paraphernalia such as ritual snuffing tubes and snuff trays are included. The text is richly illustrated with photographs and images of decorated ritual implements, and provides a comprehensive bibliography. Anadenanthera: Visionary Plant of Ancient South America explores: botanical aspects, taxonomy, and geographical distribution of Anadenanthera ethnographical, historical, and traditional aspects of Anadenanthera use chemical and pharmacological investigations of the genus and the various visionary preparations derived from itwith emphasis on the biologically active constituents theories of the mechanisms of action of the active tryptamines and carboline alkaloids comparisons of wood anatomy, morphology, and percentage of alkaloid content evaluation of stylistic and iconographic traits Anadenanthera: Visionary Plant of Ancient South America is a thorough, useful resource for archeologists, anthropologists, chemists, researchers, pre-Columbian art historians, and any layperson interested in pre-Columbian art, archeology, or visionary plants.

This book examines one of the most important demographic changes facing the United States: an overall aging population and the increasing influence of Latinos. It also looks at the changing demographics in Mexico and its impact on the health and financial well-being of aging Mexicans and Mexican Americans. The book provides a conceptual and accessible framework that will educate and inform readers about the interconnectedness of the demographic trends facing these two countries. It also explores the ultimate personal, social, and political impact they will have on all Americans, in the U.S. as well as Mexico.     Challenges of Latino Aging in the Americas features papers presented at the 2013 International Conference on Aging in the Americas, held at the University of Texas at Austin, September 2013. It brings together the work of many leading scholars from the fields of sociology, demography, psychology, anthropology, geography, social work, geriatric medicine, epidemiology, and public affairs.   Coverage in this edited collection includes working with diverse populations; culturally compatible interventions for diverse elderly; the health, mental health, and social needs and concerns of aging Latinos; and the policy, political, and bi-lateral implications of aging and diversity in the U.S. and Mexico. The book provides a rich blend of empirical evidence with insightful, cutting-edge analysis that will serve as an insightful resource for researchers and policy makers, professors and graduate students in a wide range of fields, from sociology and demography to economics and political science. ​

This dissertation focuses on the calculation of transport coefficients in the matter created in a relativistic heavy-ion collision after chemical freeze-out. This matter can be well approximated using a pion gas out of equilibrium. We describe the theoretical framework needed to obtain the shear and bulk viscosities, the thermal and electrical conductivities and the flavor diffusion coefficients of a meson gas at low temperatures. To describe the interactions of the degrees of freedom, we use effective field theories with chiral and heavy quark symmetries. We subsequently introduce the unitarization methods in order to obtain a scattering amplitude that satisfies the unitarity condition exactly, then go on to calculate the transport properties of the low-temperature phase of quantum chromodynamics - the hadronic medium - which can be used in hydrodynamic simulations of a relativistic heavy-ion collision and its subsequent evolution. We show that the shear viscosity over entropy density exhibits a minimum in a phase transition by studying this coefficient in atomic Argon (around the liquid-gas phase transition) and in the linear sigma model in the limit of a large number of scalar fields (which presents a chiral phase transition). Finally, we provide an experimental method for estimating the bulk viscosity in relativistic heavy-ion collisions by performing correlations of the fluctuating components of the stress-energy tensor.

This book examines one of the most important demographic changes facing the United States: an overall aging population and the increasing influence of Latinos. It also looks at the changing demographics in Mexico and its impact on the health and financial well-being of aging Mexicans and Mexican Americans. The book provides a conceptual and accessible framework that will educate and inform readers about the interconnectedness of the demographic trends facing these two countries. It also explores the ultimate personal, social, and political impact they will have on all Americans, in the U.S. as well as Mexico. Challenges of Latino Aging in the Americas features papers presented at the 2013 International Conference on Aging in the Americas, held at the University of Texas at Austin, September 2013. It brings together the work of many leading scholars from the fields of sociology, demography, psychology, anthropology, geography, social work, geriatric medicine, epidemiology, and public affairs. Coverage in this edited collection includes working with diverse populations; culturally compatible interventions for diverse elderly; the health, mental health, and social needs and concerns of aging Latinos; and the policy, political, and bi-lateral implications of aging and diversity in the U.S. and Mexico. The book provides a rich blend of empirical evidence with insightful, cutting-edge analysis that will serve as an insightful resource for researchers and policy makers, professors and graduate students in a wide range of fields, from sociology and demography to economics and political science.

This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

This dissertation focuses on the calculation of transport coefficients in the matter created in a relativistic heavy-ion collision after chemical freeze-out. This matter can be well approximated using a pion gas out of equilibrium. We describe the theoretical framework needed to obtain the shear and bulk viscosities, the thermal and electrical conductivities and the flavor diffusion coefficients of a meson gas at low temperatures. To describe the interactions of the degrees of freedom, we use effective field theories with chiral and heavy quark symmetries. We subsequently introduce the unitarization methods in order to obtain a scattering amplitude that satisfies the unitarity condition exactly, then go on to calculate the transport properties of the low-temperature phase of quantum chromodynamics - the hadronic medium - which can be used in hydrodynamic simulations of a relativistic heavy-ion collision and its subsequent evolution. We show that the shear viscosity over entropy density exhibits a minimum in a phase transition by studying this coefficient in atomic Argon (around the liquid-gas phase transition) and in the linear sigma model in the limit of a large number of scalar fields (which presents a chiral phase transition). Finally, we provide an experimental method for estimating the bulk viscosity in relativistic heavy-ion collisions by performing correlations of the fluctuating components of the stress-energy tensor.

Henry Jay Forman, Jon Fukuto and Martine Torres "Research is to see what everybody else has seen and to think what nobody else has thought. " -- Albert Szent-Gyorgyi Several years ago, one of us put together a book that dealt with various aspects of oxidative stress and introduced the concept of signal transduction by oxidants. Since then, the interest in the mechanisms by which reactive oxygen and nitrogen species (ROS/RNS) can modulate the cell's response has tremendously grown, paralleling the intense efforts towards identifying new signaling pathways in which phosphorylation/dephosphorylation events take center stage. Evidence is now mounting that production of these species by the cells is required for their function from growth to apoptosis and numerous signaling pathways have been identified where the participation of ROS and RNS is apparent (see Chapters 11-14, 16 and 18). Thus, the field is no more limited to the group of free radical aficionados who have pioneered this area of research but has now gone mainstream. While it is satisfactory for those of us who have been working on this topic for a long time, it has the risk of becoming the "fashionable" motto where those molecules, still mysterious to some, become responsible for everything and anything.

This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

This nine-volume set LNCS 14104 – 14112 constitutes the refereed workshop proceedings of the 23rd International Conference on Computational Science and Its Applications, ICCSA 2023, held at Athens, Greece, during July 3–6, 2023. The 350 full papers and 29 short papers and 2 PHD showcase papers included in this volume were carefully reviewed and selected from a total of 876 submissions. These nine-volumes includes the proceedings of the following workshops: Advances in Artificial Intelligence Learning Technologies: Blended Learning, STEM, Computational Thinking and Coding (AAILT 2023); Advanced Processes of Mathematics and Computing Models in Complex Computational Systems (ACMC 2023); Artificial Intelligence supported Medical data examination (AIM 2023); Advanced and Innovative web Apps (AIWA 2023); Assessing Urban Sustainability (ASUS 2023); Advanced Data Science Techniques with applications in Industry and Environmental Sustainability (ATELIERS 2023); Advances in Web Based Learning (AWBL 2023); Blockchain and Distributed Ledgers: Technologies and Applications (BDLTA 2023); Bio and Neuro inspired Computing and Applications (BIONCA 2023); Choices and Actions for Human Scale Cities: Decision Support Systems (CAHSC-DSS 2023); and Computational and Applied Mathematics (CAM 2023).

The six-volume set LNCS 10404-10409 constitutes the refereed proceedings of the 17th International Conference on Computational Science and Its Applications, ICCSA 2017, held in Trieste, Italy, in July 2017. The 313 full papers and 12 short papers included in the 6-volume proceedings set were carefully reviewed and selected from 1052 submissions. Apart from the general tracks, ICCSA 2017 included 43 international workshops in various areas of computational sciences, ranging from computational science technologies to specific areas of computational sciences, such as computer graphics and virtual reality. Furthermore, this year ICCSA 2017 hosted the XIV International Workshop On Quantum Reactive Scattering. The program also featured 3 keynote speeches and 4 tutorials.

The six-volume set LNCS 10404-10409 constitutes the refereed proceedings of the 17th International Conference on Computational Science and Its Applications, ICCSA 2017, held in Trieste, Italy, in July 2017. The 313 full papers and 12 short papers included in the 6-volume proceedings set were carefully reviewed and selected from 1052 submissions. Apart from the general tracks, ICCSA 2017 included 43 international workshops in various areas of computational sciences, ranging from computational science technologies to specific areas of computational sciences, such as computer graphics and virtual reality. Furthermore, this year ICCSA 2017 hosted the XIV International Workshop On Quantum Reactive Scattering. The program also featured 3 keynote speeches and 4 tutorials.

The five-volume set LNCS 9786-9790 constitutes the refereed proceedings of the 16th International Conference on Computational Science and Its Applications, ICCSA 2016, held in Beijing, China, in July 2016. The 239 revised full papers and 14 short papers presented at 33 workshops were carefully reviewed and selected from 849 submissions. They are organized in five thematical tracks: computational methods, algorithms and scientific applications; high performance computing and networks; geometric modeling, graphics and visualization; advanced and emerging applications; and information systems and technologies.

The five-volume set LNCS 9786-9790 constitutes the refereed proceedingsof the 16th International Conference on Computational Science and ItsApplications, ICCSA 2016, held in Beijing, China, in July 2016. The 239 revised full papers and 14 short papers presented at 33 workshops were carefully reviewed and selected from 849 submissions. They are organized in five thematical tracks: computational methods, algorithms and scientific applications; high performance computing and networks; geometric modeling, graphics and visualization; advanced and emerging applications; and information systems and technologies.

The five-volume set LNCS 9786-9790 constitutes the refereed proceedingsof the 16th International Conference on Computational Science and ItsApplications, ICCSA 2016, held in Beijing, China, in July 2016. The 239 revised full papers and 14 short papers presented at 33 workshops were carefully reviewed and selected from 849 submissions. They are organized in five thematical tracks: computational methods, algorithms and scientific applications; high performance computing and networks; geometric modeling, graphics and visualization; advanced and emerging applications; and information systems and technologies.

The five-volume set LNCS 9786-9790 constitutes the refereed proceedings of the 16th International Conference on Computational Science and Its Applications, ICCSA 2016, held in Beijing, China, in July 2016. The 239 revised full papers and 14 short papers presented at 33 workshops were carefully reviewed and selected from 849 submissions. They are organized in five thematical tracks: computational methods, algorithms and scientific applications; high performance computing and networks; geometric modeling, graphics and visualization; advanced and emerging applications; and information systems and technologies.

The five-volume set LNCS 9786-9790 constitutes the refereed proceedings of the 16th International Conference on Computational Science and Its Applications, ICCSA 2016, held in Beijing, China, in July 2016. The 239 revised full papers and 14 short papers presented at 33 workshops were carefully reviewed and selected from 849 submissions. They are organized in five thematical tracks: computational methods, algorithms and scientific applications; high performance computing and networks; geometric modeling, graphics and visualization; advanced and emerging applications; and information systems and technologies.

Henry Jay Forman, Jon Fukuto and Martine Torres "Research is to see what everybody else has seen and to think what nobody else has thought. " -- Albert Szent-Gyorgyi Several years ago, one of us put together a book that dealt with various aspects of oxidative stress and introduced the concept of signal transduction by oxidants. Since then, the interest in the mechanisms by which reactive oxygen and nitrogen species (ROS/RNS) can modulate the cell's response has tremendously grown, paralleling the intense efforts towards identifying new signaling pathways in which phosphorylation/dephosphorylation events take center stage. Evidence is now mounting that production of these species by the cells is required for their function from growth to apoptosis and numerous signaling pathways have been identified where the participation of ROS and RNS is apparent (see Chapters 11-14, 16 and 18). Thus, the field is no more limited to the group of free radical aficionados who have pioneered this area of research but has now gone mainstream. While it is satisfactory for those of us who have been working on this topic for a long time, it has the risk of becoming the "fashionable" motto where those molecules, still mysterious to some, become responsible for everything and anything.