In this issue, guest editors bring their considerable expertise to this important topic. Contains 10 relevant, practice-oriented topics including current dedicated breast imaging: recent advances and current limitations; breast cancer systemic staging (comparison of CT, bone scan, FDG PET); breast cancer treatment response (comparison of CT, bone scan, FDG PET); artificial intelligence and machine learning in breast cancer imaging; molecular classification of breast cancer; and more.  Provides in-depth clinical reviews on breast cancer: advances in molecular imaging, offering actionable insights for clinical practice.  Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. 

Nonclinical Study Contracting and Monitoring: A Practical Guide offers a systematic and straightforward handbook for obtaining high quality preclinical Good Laboratory Practice (GLP) studies. This book is full of real-world examples, processes, procedures, useful templates, checklists and sample reports to provide readers with a better understanding of exactly what happens during all stages of a GLP study and the critical aspects of GLP study design and conduct. Designed for both the novice and experienced scientist, this book covers the GLP regulations and how they impact preclinical studies, the differences between GLP, non-GLP and peer-reviewed studies, preclinical GLP study design, laboratory selection, contracts and business ethics, how to obtain test material for the study, animal sourcing and release for study, preparation of a draft report and much more. By illustrating the overall big picture and tying it together with the individual steps, this book is an essential resource to help scientists ensure a high quality GLP study that passes both scientific and regulatory scrutiny.
Includes both the "big picture" look at complex processes, such as contracting toxicology and safety studies with CROs, as well as a detailed account of each individual step.

Contains several real world examples of problems in preclinical studies to provide you with an idea of the types of challenges that are routinely encountered and how this book can help you avoid these issues.

Provides monitoring checklists through the book that will help you comply with each GLP requirement and maintain compliance throughout the entire process.

Both entry level and experienced scientists involved in nonclinical toxicology study monitoring will benefit from the ideas, examples, discussions and strategies presented throughout this book.

The chapters in this volume provide a varied yet consistent analysis of the ways in which ideologies have been used, misused, or abandoned in Latin America in the twentieth century. The volume offers scholars and students a challenging collection of interpretations of and explanations for the ways in which ideologues and ideologies have played a crucial role in the political development of the continent. And, while illuminating key reasons for the rise and fall of specific ideologies and their repeated betrayal throughout the century--from anarchism to communism, to socialism, to Peronism, to neoliberalism--the volume indicates how much there is still left to learn about the importance of ideological discourse in the mind and polity of Latin America. With chapters examining Mexico, Chile, Cuba, Paraguay, and Argentina, this work will be of interest to all Latin Americanists.

This edited collection explores how different dictators and authoritarian parties and factions have frequently succeeded in rising to power in modern Latin America, often retaining political and/or military control for long periods of time. The volume examines whether there are common factors within the Latin American sociopolitical, cultural, and historical context that have allowed authoritarianism to play such a fundamental and recurrent role in the continent's development. Including chapters on Mexico, Chile, Cuba, Paraguay, and Honduras, the work will be of interest to scholars and students alike in comparative politics, Latin American history, and Latin American studies.

This book is a study of the political development of the many factions that surfaced in Mexico from the achievement of independence in 1821 to General Antonio Lopez de Santa Anna's last government in 1853-55. Paying particular attention to the writings of the main thinkers of the period and the ways in which they inspired or were betrayed by their respective factions, this volume concentrates on the evolution of the different factions (traditionalists, moderates, radicals, and "santanistas"), who sustained their beliefs at one point or another. It follows a chronological approach and puts significant emphasis to the way the hopes of the 1820s degenerated into the despair of the 1840s, and how these in turn affected the evolution of the different factions' political proposals.

Political proposals and ideologies were important in independent Mexico; it was an age of proposals. Various constitutional projects were proposed, discussed, attempted, or dismissed. This study offers a comprehensive analysis of how the generalized liberal principles of early republican Mexico became fractured into numerous conflicting political proposals and movements. In response to the ever-changing political landscape of the new nation, the emergent Mexican political class was prevented from achieving the ever-evasive constitutional order, unity, progress, and stability all dreamed of experiencing when General Agustin de Iturbide marched into Mexico City on September 27, 1821. Appendices with a glossary, chronologies, and description of major personalities are included.

Silas Talbot’s life illuminates his time—not with greater brightness than the lives of his more famous contemporaries, but with perhaps broader range and greater insight into the experiences and circumstances of a plain citizen of the new republic—a citizen whose bravery and energy helped to create it. Silas Talbot was a farmer’s son who went to sea, learned the building trades, saved and invested his money wisely, married well several times, fought as a Rhode Island soldier in the Revolutionary War, became a lieutenant colonel, served with courage and competence, became a privateer and a prisoner-of-war in the conflict at sea, speculated in western lands, was elected to the New York State Legislature and the U.S. Congress, represented the interests of American sailors forced to serve in Britain’s navy, and finally achieved the rank of U.S. Navy captain and became the second commanding officer of the frigate USS Constitution. In a full and energetic life of sixty-two years he met and served the famous—Washington, Adams, Hamilton, Lafayette—and also raised a family; advanced in the social, political, and business circles of New York and Rhode Island; and was, as the author notes, “among the first of the new citizens of the new republic to seize its gifts.�

Makes persuasive case that Josâe Marâia Tornel y Mendâivil, spin-doctor for Antonio Lâopez de Santa Anna, was an important figure in his own right, both as a politician and a writer. Emphasizes the 'great man' school of history, but forces the reader to conclude that the first political generation of independent Mexico boasted a substantial crew of extraordinary personalities"--Handbook of Latin American Studies, v. 58.

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Does the wind blow? is the eighth Reader of Level 1 in the Aweh! English First Additional Language reading scheme. Aweh! is a graded reading scheme that will awaken any child's imagination as they join Mama Africa in saving the world's stories by charging the Umthombo; the well of stories. The bright and colourful artwork provides a child-centred learning opportunity that integrates both the weekly Mathematics concept and the Life Skills topic. The inside cover identifies the key vocabulary and phonic focus for every Reader. The back inside cover offers a fun writing activity to consolidate the child's understanding and to link reading to writing.

Where is Lelo? is the fith Reader of Level 1 in the Aweh! English First Additional Language reading scheme. Aweh! is a graded reading scheme that will awaken any child's imagination as they join Mama Africa in saving the world's stories by charging the Umthombo; the well of stories. The bright and colourful artwork provides a child-centred learning opportunity that integrates both the weekly Mathematics concept and the Life Skills topic. The inside cover identifies the key vocabulary and phonic focus for every Reader. The back inside cover offers a fun writing activity to consolidate the child's understanding and to link reading to writing.

Let's stay safe is the fourth Reader of Level 2 in the Aweh! English First Additional Language reading scheme. Aweh! is a graded reading scheme that will awaken any child's imagination as they join Mama Africa in saving the world's stories by charging the Umthombo; the well of stories. The bright and colourful artwork provides a child-centred learning opportunity that integrates both the weekly Mathematics concept and the Life Skills topic. The inside cover identifies the key vocabulary and phonic focus for every Reader. The back inside cover offers a fun writing activity to consolidate the child's understanding and to link reading to writing.

Who stole Sam's necklaces the first Reader of Level 3 in the Aweh! English First Additional Language reading scheme. Aweh! is a graded reading scheme that will awaken any child's imagination as they join Mama Africa in saving the world's stories by charging the Umthombo; the well of stories. The bright and colourful artwork provides a child-centred learning opportunity that integrates both the weekly Mathematics concept and the Life Skills topic. The inside cover identifies the key vocabulary and phonic focus for every Reader. The back inside cover offers a fun writing activity to consolidate the child's understanding and to link reading to writing.

Zazi and the ants is the second Reader of Level 1 in the Aweh! English First Additional Language reading scheme. Aweh! is a graded reading scheme that will awaken any child's imagination as they join Mama Africa in saving the world's stories by charging the Umthombo; the well of stories. The bright and colourful artwork provides a child-centred learning opportunity that integrates both the weekly Mathematics concept and the Life Skills topic. The inside cover identifies the key vocabulary and phonic focus for every Reader. The back inside cover offers a fun writing activity to consolidate the child's understanding and to link reading to writing.