This volume introduces some basic mathematical models for cell cycle, proliferation, cancer, and cancer therapy. Chapter 1 gives an overview of the modeling of the cell division cycle. Chapter 2 describes how tumor secretes growth factors to form new blood vessels in its vicinity, which provide it with nutrients it needs in order to grow. Chapter 3 explores the process that enables the tumor to invade the neighboring tissue. Chapter 4 models the interaction between a tumor and the immune system. Chapter 5 is concerned with chemotherapy; it uses concepts from control theory to minimize obstacles arising from drug resistance and from cell cycle dynamics. Finally, Chapter 6 reviews mathematical results for various cancer models.

The concept and reality of revolution has gripped the imagination of many writers over the centuries. This is a comprehensive historical examination of these key ideas and theories. Kimmel looks at the writings of Marx, Weber, Tocqueville, Freud, and Durkheim, asking how their theories were affected by the reality of living through the revolutions of 1848 and 1917. Kimmel then examines the interpretations of revolution offered by social scientists in the post World War II period, including Theda Skocpol, Barrington Moore and Charles Tilly, among others. The work is brought fully up-to-date with current analyses of the Nicaraguan, Iranian and Angolan revolutions.

This paper describes the development of a methodology for sizing Blended-Wing-Body (BWB) transports and how the capabilities of the Flight Optimization System (FLOPS) have been expanded using that methodology. In this approach, BWB transports are sized based on the number of passengers in each class that must fit inside the centerbody or pressurized vessel. Weight estimation equations for this centerbody structure were developed using Finite Element Analysis (FEA). This paper shows how the sizing methodology has been incorporated into FLOPS to enable the design and analysis of BWB transports. Previous versions of FLOPS did not have the ability to accurately represent or analyze BWB configurations in any reliable, logical way. The expanded capabilities allow the design and analysis of a 200 to 450-passenger BWB transport or the analysis of a BWB transport for which the geometry is already known. The modifications to FLOPS resulted in differences of less than 4 percent for the ramp weight of a BWB transport in this range when compared to previous studies performed by NASA and Boeing.

2014 COMPTON CROOK AWARD FINALIST.

The Brogardi appeared out of nowhere, and -- telegraphing their peaceful intentions -- they landed in the middle of nowhere: New York State's Catskills Mountains resorts. It was an alien invasion, of the most peaceful, friendly kind. But there had to be something sinister behind it all, right?

Movie executive Jake Berman lives fiction for a living, promoting movies to the masses. He's happy, and only moderately harried. But his peaceful existence is thrown into overdrive when one of the aliens sets his sights beyond the decaying resorts of the east -- when he decides it's time to invade Hollywood

Daniel M. Kimmel is a film critic and professor of film. His book on the history of FOX TV, "The Fourth Network" received the Cable Center Book Award. His other books include a history of DreamWorks, "The Dream Team," and "I'll Have What She's Having: Behind the Scenes of the Great Romantic Comedies." His collection of essays, "Jar Jar Binks Must Die... and other Observations about Science Fiction Movies," was a 2012 nominee for the Hugo Award for Best Related Work. He is a past president of the Boston Society of Film Critics, and current co-chair of the Boston Online Film Critics Association. This is his first novel.

" Kimmel's first novel is] a true joy... let's hope there are more to come." --Don Sakers, "Analog Science Fiction and Fact"

"This is the book we've been waiting for from Dan Kimmel -- funny, knowing, fast paced, full of humor, and told with a big heart. An absolute joy." ---Robert J. Sawyer, Hugo Award-winning author of "Red Planet Blues"

"Dan Kimmel's first novel is a funny and delightful tour de force that will appeal to movie fans as well as science-fiction readers." --Michael A. Burstein, John W. Campbell Award-winning author of "I Remember the Future"

"Exceptionally funny... pretty damned spectacular... this is the funniest book of the year and one of the best debut SF novels in ages " --Chris Garcia, "The Drink Tank"