This volume describes important medical discoveries, from the introduction of the first antibiotic to the present, where serendipity, intuition, coincidence, or laboratory accident played an important role in bringing a discovery to light. Although chance is the principal determinant, the book emphasizes other factors, such as economic and political exigencies and being in the right place at the right time.

For thousands of years mint has enjoyed an honored place in pharmacopoeias and kitchen cupboards in India, China, Europe, North America, and elsewhere. Today the amount of essential oils produced from the four major mint species (cornmint, peppermint, Native spearmint, and Scotch spearmint) exceeds 23,000 metric tonnes annually with a market value of more than $400 million. This makes mint the most economically important essential oil. Continuing in the esteemed tradition of the previous volumes in the Medicinal and Aromatic Plant Series, Mint: The Genus Mentha presents an in-depth look at the genus, providing information on its history, production, chemical constituents, market trends, and medicinal and nutritional uses. Beginning with a review of the correct taxonomy and proper distillation and extraction methods, the text then expands on many detailed and complex aspects of the cultivation, processing, and quality assessment of the different types of mint. Outlining recent studies on the biosynthesis and biotechnology of improved potential for oil production, the text also includes theoretical aspects of distillation used to achieve efficient and cost effective oil isolation. Variations in chemical components in oils, even within a given species, by regional or environmental circumstance is the focus of a large portion of this book. The influence of these quantitative differences is explored in chapters on characterization, selection, and quality control methods including gas chromatographic profiles. The practice of ameliorating these variations with diluted or adulterated blends to produce a consistent product characteristic is also evaluated. The final portion of the book examines the role mint plays in the pharmaceutical, personal and oral care, aromatherapy, and flavor industries including confections, tobacco, and alcohol. With extensive information from internationally known experts in their field, Mint: The Genus Mentha is an invaluable companion for all those actively engaged in the research, cultivation, marketing, or product development of mint.

This study is part of a series dedicated to the publication of reviews by experts of important topics in all areas of echinoderm studies, from molecular biology to ecology, palaeontology, biology and taxonomy. It addresses a range of topics in depth. The reviews seek to provide access to the field and to give direction to further study and research.

This work consists of seven plenary lectures read at an international conference in Tampa, USA.

The purpose of this book is to present the state of knowledge concerning nutrition and point out directions for future work for the Echinodermata, an ancient group which shows great diversity in form and function, and whose feeding activities can have great environmental impact.

This volume contains abstracts of all papers presented at the International Echinoderms Conferences, and complete papers of those which were submitted for publication and accepted upon recommendation of referees.

Spain's First Carlist War was an unlikely agent of modernity. It pitted town against country, subalterns against elites, and Europe's Liberal powers against Absolute Monarchies. This book traces the individual, collective and international experience of this conflict, giving equal attention to battle fronts and home fronts.

Spain's First Carlist War was an unlikely agent of modernity. It pitted town against country, subalterns against elites, and Europe's Liberal powers against Absolute Monarchies. This book traces the individual, collective and international experience of this conflict, giving equal attention to battle fronts and home fronts.

This richly illustrated book describes the use of interactive and dynamic graphics as part of multidimensional data analysis. Chapter topics include clustering, supervised classification, and working with missing values. A variety of plots and interaction methods are used in each analysis, often starting with brushing linked low-dimensional views and working up to manual manipulation of tours of several variables. The book is augmented by a wealth of online material.

It's the questions that drive us.
What is real?
How do you know what is real?
Can we be certain that we are not in a Matrix ourselves?
Does free will exist inside the Matrix? Does it exist outside the Matrix?
Are our minds just our brains?
Are sentient machines possible?
Is it ever best to take the blue pill?

It's the questions that brought you here.

The "Matrix" films are not just about Kung Fu and special effects. Rather, they are about knowledge, reality, consciousness, freedom, fate, foreknowledge, good, evil, faith, enlightenment, and the very meaning of existence. In short, they are about philosophy - with some impressive special effects on the side.

"Like a Splinter in Your Mind" guides you through thirteen of the core philosophical questions that are explored in the "Matrix" films. You will see how Morpheus manifests Kierkegaard's philosophy of faith, how Neo, the Merovingian, and Ghost exemplify the three major positions on free will, how the objectivity of value judgments are challenged by Agent Smith, and much more.

Matt Lawrence brings a philosopher's insight to all three of the "Matrix "films, giving us a better appreciation of the trilogy, and a solid grasp of key issues in metaphysics, epistemology, ethics, philosophy of mind, race and gender, existentialism, Taoism and mysticism. And while his focus is squarely on the films, he also shows us how these questions relate to our own lives and our own philosophical journeys.

Here is an antidote to the stifling academic grind brought on by accountability testing. It demonstrates how mastery of skills can be a joy rather than a chore and describes in detail a highly successful program of structured skill-mastery centers that engage students independently while the teacher works closely with a small group. This system of managing the classroom helps the teacher provide materials that match the many achievement levels of children in the classroom. Typically in use for 60-90 minutes in a school day, up to four days a week, the system works well with the whole language or the guided practice approaches to reading. The program, developed by Carolyn Lawrence, is being used successfully throughout 63 elementary schools in one Florida school district. Many of the schools are nationally recognized for their achievement in test scores. The ideas in this book are simple, clear, and ready to use to bring back excitement, freedom, and smiles to children in their classroom life. Students are eager to get to the skill practice work in the mastery centers, largely because they get to use a variety of manipulative materials matched to their levels. These materials are inexpensive, readily available and described in the book. This book will be of interest to professors of education, superintendents, curriculum and instruction educators, principals, teachers, and parents.

Originally a sect within the Anglican church, Methodism blossomed into a dominant mainstream religion in America during the nineteenth century. At the beginning, though, Methodists constituted a dissenting religious group whose ideas about sexuality, marriage, and family were very different from those of their contemporaries.Focusing on the Methodist notion of family that cut across biological ties, "One Family Under God" speaks to historical debates over the meaning of family and how the nuclear family model developed over the eighteenth century. Historian Anna M. Lawrence demonstrates that Methodists adopted flexible definitions of affection and allegiance and emphasized extended communal associations that enabled them to incorporate people outside the traditional boundaries of family. They used the language of romantic, ecstatic love to describe their religious feelings and the language of the nuclear family to describe their bonds to one another. In this way, early Methodism provides a useful lens for exploring eighteenth-century modes of family, love, and authority, as Methodists grappled with the limits of familial and social authority in their extended religious family.Methodists also married and formed conjugal families within this larger spiritual framework. Evangelical modes of marriage called for careful, slow courtships, and often marriages happened later in life and produced fewer children. Religious views of the family offered alternatives to traditional coupling and marriage--through celibacy, spiritual service, and the idea of finding one's true spiritual match, which both challenged the role of parental authority within marriage-making and accelerated the turn within the larger society toward romantic marriage.By examining the language and practice of evangelical sexuality and family, "One Family Under God" highlights how the Methodist movement in the eighteenth century was central to the rise of romantic marriage and the formation of the modern family.

Sea Urchins: Biology and Ecology, Fourth Edition, Volume 43 expands its coverage to include the entire class of Echinoidea, making this new edition an authoritative reference of the entire class of species. This is a valuable resource that will help readers gain a deep understanding of the basic characteristics of sea urchins, the basis of the great variation that exists in sea urchins, and how sea urchins are important components of marine ecosystems. Updated coverage includes sections on reproduction, metabolism, endocrinology, larval ecology, growth, digestion, carotenoids and disease.

Written and edited by leading physicians, Breastfeeding: A Guide for the Medical Profession, 9th Edition, offers comprehensive, dependable information and guidance in this multifaceted field. Award-winning author and co-founder of the Academy of Breastfeeding Medicine, Dr. Ruth Lawrence, and her son, Dr. Rob Lawrence, ensure that you're brought fully up to date on everything from basic data on the anatomical, physiological, biochemical, nutritional, immunological, and psychological aspects of human lactation, to the problems of clinical management of breastfeeding-all in a highly readable, easily accessible desk reference. Helps you make appropriate drug recommendations, treat conditions associated with breastfeeding, and provide thoughtful guidance to the breastfeeding mother according to her circumstances, problems, and lifestyle. Includes numerous charts and tables throughout, with an emphasis on the scientific, chemical, and physiological underpinnings of breastfeeding. Appendices contain additional charts and tables, including the complete collection of clinical protocols on breastfeeding and human milk from the Academy of Breastfeeding Medicine. Features new chapters on breast conditions and their management in the breastfeeding mother, breastfeeding and chest-feeding for LGBTQ+ families, breastfeeding during disasters, and establishing a breastfeeding practice or academic department. Provides significant updates on physiology and biochemistry of lactation; medications and herbal preparations in breast milk; transmission of infectious disease through breast milk; allergy and its relationship with breastfeeding, exposure, and avoidance; premature infants and breastfeeding; and practical management of the mother-infant nursing couple. Offers authoritative and fresh perspectives from new associate editors: neonatologist Dr. Larry Noble, obstetrician Dr. Alison Stuebe, and pediatrician and lactation specialist Dr. Casey Rosen-Carole. Covers patient-centered counseling, the cellular composition of human breast milk, microbiota of the breast and human milk, and the multifunctional roles of human milk oligosaccharides (HMOs). Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This fully revised and expanded edition of "Sea Urchins" provides a wide-ranging understanding of the biology and ecology of this key component of the world's oceans. Coverage includes reproduction, metabolism, endocrinology, larval ecology, growth, digestion, carotenoids, disease and nutrition. Other chapters consider the ecology of individual species that are of major importance ecologically and economically, including species from Japan, New Zealand, Australia, Europe, North America, South America and Africa. In addition, six new contributions in areas such as immunology, digestive systems and community ecology inform readers on key recent developments and insights from the literature.

Sea urchins are ecologically important and often greatly affect marine communities. Because they have an excellent fossil record, they are also of interest to paleontologists. Research on sea urchins has increased in recent years, stimulated first by recognition of their ecological importance and subsequently their economic importance. Scientists around the world are actively investigating their potential for aquaculture and fisheries, and their value as model systems for investigations in developmental biology continues to increase.
Continues the series "Developments in Aquaculture and Fisheries Science" with a newly revised volume

Collects and synthesizes the state of knowledge of sea urchin biology and ecologyExpanded from previous edition to include non-edible species, providing the needed basis for broader evolutionary understanding of sea urchins