This issue of Critical Care Clinics will focus on Severe Acute Respiratory DIstress Syndrome and dealing with it in the ICU. Topics will include: Challenges and Successes in ARDS Research;Mechanical ventilation with Lung Protective Strategies: What works?; Gene therapy for ALI/ARDS;High Frequency Oscillatory Ventilation in ALI/ARDS;Prone positioning therapy in ARDS;Recovery and Long-term outcome in ARDS; and Experimental models and emergeing hypotheses for ALI and ARDS

Hemoglobin-based Oxygen Carriers is an exciting and evolving alternative to blood transfusion. This issue explores its potential with topics on: "HBOCs from Human or Bovine Hemoglobin," "Comparison of HBOCs to Stored Human Red Blood Cells," "HBOCs and Tissue Oxygenation," "HBOCs: Role in surgery, resuscitation or hemorrhagic shock?" and more!

Guest editor Lena Napolitano has assembled and expert team of authors on the topic of Surgery in the ICU. Articles will focus on: Oxygen Support and Mechanical Ventilation Advances; Ventilator-associated Pneumonia - New Definitions;Optimal Strategies for Severe ARDS; Persistent Inflammation/Immunosuppression Syndrome; ABCDE Bundle in Critical Care;Renal Replacement Therapy in Acute Kidney Injury: Consensus?; Transfusion Advances in Critical Care; Severe Sepsis and Septic Shock: ProCESS; ARISE: PROMISE - What is Optimal Resuscitation?; Nutritional Support in Critical Care: What is the Evidence?; Acute Kidney Injury and Outcomes; and Tracheostomy Update: When and How?

Guest editor Lena Napolitano has assembled an expert team of authors on the topic of Trauma in the ICU. Articles will focus on: Non-compressible Torso Hemorrhage; Prediction of Massive Transfusion in Trauma; Coagulopathy of Trauma; Viscoelastic testing and Hyperfibrinolysis in Trauma; Tranexamic Update in Trauma; Optimal Reversal of Novel Anticoagulants in Trauma; Optimal Transfusion for Traumatic Hemorrhagic Shock; and more!

These proceedings of a well-established conference on numerical methods, calculations, and modelling in fluid dynamics concentrates on five topics: multidimensional upwinding, turbulent flows, domain decomposition methods, unstructured grids, and flow visualization, and it includes papers presented at a workshop on all-vertex schemes. All papers have been carefully refereed.

Napolitano's Aircraft Dynamics is designed to help readers extrapolate from low level formulas, equations, and details to high level comprehensive views of the main concepts. The text also helps readers with fundamental skills of learning the "basic modeling" of the aircraft aerodynamics and dynamics. The main objective is to organize the topics in "modular blocks" each of them leading to the understanding of the inner mechanisms of the aircraft aerodynamics and dynamics, eventually leading to the development of simple flight simulations schemes.