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Being a complex disease that affects millions of people world over,
cancer research has assumed great significance. Translational
cancer research transforms scientific discoveries in the laboratory
or population studies into clinical application to reduce incidence
of cancer , morbidity and mortality. It is becoming increasingly
evident that cancer is a preventable disease. The IVth
International Symposium on Translational Cancer Research held in
Udaipur, India in December 2011, discussed various aspects of the
biological processes in cancer cells and approaches to cancer
prevention. A few contributions from this meeting are presented in
this book, providing an in depth analysis of data on cancer
prevention and therapeutics. These contributions are either
critical reviews or research reports. The topics discussed include
evidence-based nutritional recommendations for cancer patients and
survivors, risk factors such as stress, enrichment of tumour stem
cells by anticancer drug treatment contributing to tumour
recurrence and the mechanism of anticancer effects of various
natural products. Chemosensitizing effect of curcumin, anti-cancer
effect of products from neem, action of sulforaphane and cytotoxic
effect of a number of novel synthetic coordination complexes of
trace metals have been discussed. Novel molecular targets of
angiogenesis and molecular basis of the gender bias to thyroid
cancer have also been discussed . This book provides useful
information on translational cancer research to clinicians and
biomedical scientists.
Being a complex disease that affects millions of people world over,
cancer research has assumed great significance. Translational
cancer research transforms scientific discoveries in the laboratory
or population studies into clinical application to reduce incidence
of cancer , morbidity and mortality. It is becoming increasingly
evident that cancer is a preventable disease. The IVth
International Symposium on Translational Cancer Research held in
Udaipur, India in December 2011, discussed various aspects of the
biological processes in cancer cells and approaches to cancer
prevention. A few contributions from this meeting are presented in
this book, providing an in depth analysis of data on cancer
prevention and therapeutics. These contributions are either
critical reviews or research reports. The topics discussed include
evidence-based nutritional recommendations for cancer patients and
survivors, risk factors such as stress, enrichment of tumour stem
cells by anticancer drug treatment contributing to tumour
recurrence and the mechanism of anticancer effects of various
natural products. Chemosensitizing effect of curcumin, anti-cancer
effect of products from neem, action of sulforaphane and cytotoxic
effect of a number of novel synthetic coordination complexes of
trace metals have been discussed. Novel molecular targets of
angiogenesis and molecular basis of the gender bias to thyroid
cancer have also been discussed . This book provides useful
information on translational cancer research to clinicians and
biomedical scientists.
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