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Imagine scientists controlling the transmission of certain diseases through the genetic modification of mosquitoes. Eradicating harmful insects without the use of pesticides. Or increasing the fertility of some insects who in turn eat harmful arthropods or even a plant pathogen. Those are just a few of the real-world applications of insect transgenesis, which offers substantial benefits to humankind-whether it be in improving agricultural productivity or reducing the spread of insect-vectored diseases. Insect Transgenesis: Methods and Applications is the first publication to describe in a comprehensive manner the various methodologies available, possible applications, and the risk assessment and regulatory issues involved in this fascinating area of research. Divided into several areas of interest, the book starts with an overview of the history and methodology of insect gene transfer. The book then examines gene targeting by homologous recombination and recombination systems, and systems for transgenic selection, including visible eye color markers, chemical resistance, and fluorescent proteins. Other sections consider the use of various vector systems to integrate DNA into a host genome or to express foreign genes in a host organism. The work concludes with strategies for the use of transgenic insects, including examples for agricultural pests and vectors of disease. Of particular interest are the final chapters that discuss risk assessment considerations and governmental regulatory procedures for the transport and release of transgenic insects.
Imagine scientists controlling the transmission of certain diseases
through the genetic modification of mosquitoes. Eradicating harmful
insects without the use of pesticides. Or increasing the fertility
of some insects who in turn eat harmful arthropods or even a plant
pathogen. Those are just a few of the real-world applications of
insect transgenesis, which offers substantial benefits to
humankind-whether it be in improving agricultural productivity or
reducing the spread of insect-vectored diseases. Insect
Transgenesis: Methods and Applications is the first publication to
describe in a comprehensive manner the various methodologies
available, possible applications, and the risk assessment and
regulatory issues involved in this fascinating area of research.
Divided into several areas of interest, the book starts with an
overview of the history and methodology of insect gene transfer.
The book then examines gene targeting by homologous recombination
and recombination systems, and systems for transgenic selection,
including visible eye color markers, chemical resistance, and
fluorescent proteins. Other sections consider the use of various
vector systems to integrate DNA into a host genome or to express
foreign genes in a host organism. The work concludes with
strategies for the use of transgenic insects, including examples
for agricultural pests and vectors of disease. Of particular
interest are the final chapters that discuss risk assessment
considerations and governmental regulatory procedures for the
transport and release of transgenic insects.
Elgar Research Agendas outline the future of research in a given
area. Leading scholars are given the space to explore their subject
in provocative ways, and map out the potential directions of
travel. They are relevant but also visionary. We face many
important global environmental problems today, including climate
change, biodiversity destruction, and environmental health issues.
Key among the tools we have to understand and solve these problems
is research. This Research Agenda argues for a transdisciplinary
approach to the study of environmental management to provide better
understanding and outcomes leading to practical solutions. By
describing the key strategies needed to overcome common global
environmental challenges and to undertake successful
interdisciplinary environmental research, this Research Agenda
demonstrates the possibilities for successful transdisciplinary
environmental research. A series of case studies shows how this
transdisciplinary approach to research has improved understandings
of environmental problems and their potential solutions. Discussing
the types of participation required and the difficulties of
incorporating diverse groups into research projects, this Research
Agenda provides lessons in how to successfully undertake
transdisciplinary research in order to meet these challenges. A
Research Agenda for Environmental Management provides invaluable
insights for interdisciplinary researchers in all fields affected
by environmental management as well as students and scholars
engaged in environmental research looking for ways to successfully
integrate transdisciplinary approaches into their work.
Contributors include: J. Abrams, D.B. Agusdinata, G. Alonso-Yanez,
B. Barnett, N. Basiliko, K. Calvert, D. Cordoba, T. de Souza, M.
del Carmen Fragoso Medina, J.L. Dunn, A. Eastmond, D.J. Flaspohler,
K. Floress, V.S. Gagnon, A. Giang, H.S. Gorman, R.B. Guerrero, K.E.
Halvorsen, R.M. Handler, M.A. Hanif, R.J. Heffron, J. Heyman, L.
House-Peters, A. Kantamneni, J.L. Knowlton, R.A. LaFave, J. Licata,
H.K. Lukosch, E.E. Mata-Zayas, R. Medeiros, M.A. Mesa-Jurado, D.
Minakata, A. Mirchi, C. Moseley, T. Moya Mose, T.H. Mwampamba,
C.J.V. Navarrete, E.A. Nielsen, M. Ohira, E. Ortega, J.A.
Perlinger, E.C. Pischke, E.W. Prehoda, V.D.P. Risso, J.C.
Sacramento-Rivero, M. Samimi, D. Sanchez, C. Schelly, T.L. Selfa,
R. Shwom, R.V. Sidortsov, B. Tarekegne, G. Tchobanoglous, N.R.
Urban, L.P. Volkow, S. Walker, D. Watkins, R.L. Winkler
The Space Telecommunications Radio System (STRS) defines an open
architecture for software defined radios. This document describes
the testing methodology to aid in determining the degree of
compliance to the STRS architecture. Non-compliances are reported
to the software and hardware developers as well as the NASA project
manager so that any non-compliances may be fixed or waivers issued.
Since the software developers may be divided into those that
provide the operating environment including the operating system
and STRS infrastructure (OE) and those that supply the waveform
applications, the tests are divided accordingly. The static tests
are also divided by the availability of an automated tool that
determines whether the source code and configuration files contain
the appropriate items. Thus, there are six separate step-by-step
test procedures described as well as the corresponding requirements
that they test. The six types of STRS compliance tests are: STRS
application automated testing, STRS infrastructure automated
testing, STRS infrastructure testing by compiling WFCCN with the
infrastructure, STRS configuration file testing, STRS application
manual code testing, and STRS infrastructure manual code testing.
Examples of the input and output of the scripts are shown in the
appendices as well as more specific information about what to
configure and test in WFCCN for non-compliance. In addition, each
STRS requirement is listed and the type of testing briefly
described. Attached is also a set of guidelines on what to look for
in addition to the requirements to aid in the document review
process.
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