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The book focuses on implications of traditional and processed foods
for autism spectrum disorder (ASD) intervention and management.
Numerous phytonutrients and pharmacologically active compounds in
edible natural products and diet could influence and offer
protection to neuronal dysfunction that occurs due to ASD. The
neuroprotective effects of various fruits, vegetables, nuts and
seeds phytochemicals, and other natural bioactive ingredients
against ASD and related conditions are discussed. Topics such as
the possible neuroprotective mechanism of action of these foods and
the therapeutic role of antioxidants in relation to ASD are
addressed. This book also highlights the scope of using
anti-inflammatory agents and antioxidants to promote neurogenesis
and improve other symptoms in ASD. It emphasizes personalized
nutritional approaches with dietary management of
neurodevelopmental disorders/ASD cases. Information in this book is
relevant to researchers in the field of complementary and
alternative medicine, nutraceuticals, neuroscience, agriculture,
nutrition, and food science. This volume is beneficial to students
of varying levels, and across multiple disciplines.
The book focuses on implications of traditional and processed foods
for autism spectrum disorder (ASD) intervention and management.
Numerous phytonutrients and pharmacologically active compounds in
edible natural products and diet could influence and offer
protection to neuronal dysfunction that occurs due to ASD. The
neuroprotective effects of various fruits, vegetables, nuts and
seeds phytochemicals, and other natural bioactive ingredients
against ASD and related conditions are discussed. Topics such as
the possible neuroprotective mechanism of action of these foods and
the therapeutic role of antioxidants in relation to ASD are
addressed. This book also highlights the scope of using
anti-inflammatory agents and antioxidants to promote neurogenesis
and improve other symptoms in ASD. It emphasizes personalized
nutritional approaches with dietary management of
neurodevelopmental disorders/ASD cases. Information in this book is
relevant to researchers in the field of complementary and
alternative medicine, nutraceuticals, neuroscience, agriculture,
nutrition, and food science. This volume is beneficial to students
of varying levels, and across multiple disciplines.
This book comprehensively reviews the proteins associated with
neurodevelopmental disorders, including autism spectrum disorder
(ASD) and attention deficit hyperactivity disorder (ADHD). It also
discusses the interactions of the associated-proteins, like
bromodomain-containing proteins (BCPs), kinases, synaptic proteins,
scaffolding proteins, transcriptional factors, and DNA-binding
proteins at the subcellular and molecular levels. The book also
explores the potential of these proteins as a druggable target and
a biomarker in the neurodevelopmental disorders. The book further
explores the recent advancements in understanding the important
role of epigenetic factors in predisposition to these diseases.
Lastly, it presents genetic factors that lead to variation in gene
expression in these diseases, disorders management via diet
intervention and the future potential of stem cell therapy.
This book comprehensively reviews the proteins associated with
neurodevelopmental disorders, including autism spectrum disorder
(ASD) and attention deficit hyperactivity disorder (ADHD). It also
discusses the interactions of the associated-proteins, like
bromodomain-containing proteins (BCPs), kinases, synaptic proteins,
scaffolding proteins, transcriptional factors, and DNA-binding
proteins at the subcellular and molecular levels. The book also
explores the potential of these proteins as a druggable target and
a biomarker in the neurodevelopmental disorders. The book further
explores the recent advancements in understanding the important
role of epigenetic factors in predisposition to these diseases.
Lastly, it presents genetic factors that lead to variation in gene
expression in these diseases, disorders management via diet
intervention and the future potential of stem cell therapy.
This book focuses on the principles, methods, and interpretation
involved in establishing the safety, risk, and hazard assessment of
small molecules. It presents the regulatory requirements for risk
and hazard identification as per the guidelines of the Organization
for Economic Cooperation and Development (OECD), Paris, and the
International Council for Harmonisation (ICH) of Technical
Requirements for Pharmaceuticals for Human Use ICH and Schedule
'Y', India. It serves as reference material for undergraduate and
postgraduate pharmacy degree students as well as senior researchers
to learn about the principles, methods, and interpretations of
systemic dosage (acute and repeated dose) and genotoxicity (in
vitro and in vivo), special toxicological investigations such as
reproductive and developmental toxicology, carcinogenicity, and
toxicokinetics using animal models or in vitro methods, as
applicable. This book is the first of its kind in providing
information on the principles and methods of implementation of Good
Laboratory Practice based on the guidelines of OECD. It includes
detailed chapters about the regulatory requirements and guidelines
in pharmaceutical products and agrochemicals. It also describes the
infrastructure needed for preclinical studies, including in vivo
and in vitro facilities.
This book is intended for a diverse audience including football
fans from various parts of the world visiting Qatar for the first
time. It is estimated that at least one million people will visit
Qatar during the FIFA World Cup 2022. We planned this book to be
informative, insightful and holistic. The book covers highly
relevant subjects to football, from sport infrastructure, elite
athletes' performance, the sport's role in health, media, and
climate, to sport enthusiast experience.
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